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    ZNF474 zinc finger protein 474 [ Homo sapiens (human) ]

    Gene ID: 133923, updated on 7-Apr-2024

    Summary

    Official Symbol
    ZNF474provided by HGNC
    Official Full Name
    zinc finger protein 474provided by HGNC
    Primary source
    HGNC:HGNC:23245
    See related
    Ensembl:ENSG00000164185 AllianceGenome:HGNC:23245
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Predicted to enable metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis (RPKM 4.0), lung (RPKM 1.1) and 3 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See ZNF474 in Genome Data Viewer
    Location:
    5q23.2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (122129546..122153569)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (122646426..122670425)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (121465241..121489264)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105379149 Neighboring gene uncharacterized LOC105379148 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:121297323-121297861 Neighboring gene serum response factor binding protein 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:121412305-121412822 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:121412823-121413340 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr5:121434535-121435734 Neighboring gene Sharpr-MPRA regulatory region 13182 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr5:121464631-121465830 Neighboring gene ZNF474 antisense RNA 1 Neighboring gene lysyl oxidase Neighboring gene zinc finger protein 475 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr5:121602368-121603567 Neighboring gene NANOG hESC enhancer GRCh37_chr5:121632489-121632990 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16268 Neighboring gene synuclein alpha interacting protein Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:121705022-121705522 Neighboring gene ancient vomeronasal 1 receptor pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    zinc finger protein 474
    Names
    4933409D10Rik
    TSZFP
    testis-specific zinc finger protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_207317.3NP_997200.1  zinc finger protein 474

      See identical proteins and their annotated locations for NP_997200.1

      Status: VALIDATED

      Source sequence(s)
      AK290985, AY461732, DB058648
      Consensus CDS
      CCDS4130.1
      UniProtKB/Swiss-Prot
      A8K4M0, Q6S9Z5, Q96M07
      Related
      ENSP00000296600.4, ENST00000296600.5
      Conserved Domains (1) summary
      pfam13913
      Location:283307
      zf-C2HC_2; zinc-finger of a C2HC-type

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      122129546..122153569
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      122646426..122670425
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)