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    CEACAM20 carcinoembryonic antigen related cell adhesion molecule 20 [ Homo sapiens (human) ]

    Gene ID: 125931, updated on 17-Jun-2019

    Summary

    Official Symbol
    CEACAM20provided by HGNC
    Official Full Name
    carcinoembryonic antigen related cell adhesion molecule 20provided by HGNC
    Primary source
    HGNC:HGNC:24879
    See related
    Ensembl:ENSG00000273777
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    UNQ9366
    Expression
    Biased expression in small intestine (RPKM 13.3), duodenum (RPKM 12.5) and 1 other tissue See more
    Orthologs

    Genomic context

    See CEACAM20 in Genome Data Viewer
    Location:
    19q13.31
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (44501309..44530101, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (45010211..45033548, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 285B (pseudogene) Neighboring gene zinc finger protein 180 Neighboring gene Sharpr-MPRA regulatory region 2061 Neighboring gene carcinoembryonic antigen related cell adhesion molecule 22, pseudogene Neighboring gene uncharacterized LOC107985305 Neighboring gene immunoglobulin superfamily member 23

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    General gene information

    Homology

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of cytokine production IEA
    Inferred from Electronic Annotation
    more info
     
    response to bacterium IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    apical plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    microvillus membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    carcinoembryonic antigen-related cell adhesion molecule 20
    Names
    GPAD9366

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102597.3NP_001096067.2  carcinoembryonic antigen-related cell adhesion molecule 20 isoform 5L precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5L) represents the longest transcript and encodes the longest isoform (5L).
      Source sequence(s)
      AC245748, AY358129, EU008600
      Consensus CDS
      CCDS74393.1
      UniProtKB/Swiss-Prot
      Q6UY09
      UniProtKB/TrEMBL
      A0A087WYM6, A7LFK7
      Related
      ENSP00000481937.1, ENST00000614924.4
      Conserved Domains (2) summary
      pfam13927
      Location:361420
      Ig_3; Immunoglobulin domain
      cl11960
      Location:266343
      Ig; Immunoglobulin domain
    2. NM_001102598.3NP_001096068.2  carcinoembryonic antigen-related cell adhesion molecule 20 isoform 4S precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4S) lacks an alternate in-frame exon in both the central and 3' coding regions, compared to variant 5L, resulting in an isoform (4S) that is shorter than isoform 5L.
      Source sequence(s)
      AC245748, AY358129, EU008600, EU008601
      Consensus CDS
      CCDS74390.1
      UniProtKB/Swiss-Prot
      Q6UY09
      UniProtKB/TrEMBL
      A0A087WYH6, A7LFK7, A7LFK8
      Related
      ENSP00000481812.1, ENST00000620096.4
      Conserved Domains (4) summary
      smart00410
      Location:175247
      IG_like; Immunoglobulin like
      pfam13895
      Location:175247
      Ig_2; Immunoglobulin domain
      pfam16821
      Location:379435
      C_Hendra; C protein from hendra and measles viruses
      cl11960
      Location:266343
      Ig; Immunoglobulin domain
    3. NM_001102599.3NP_001096069.2  carcinoembryonic antigen-related cell adhesion molecule 20 isoform 4L precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4L) lacks an alternate in-frame exon in the central coding region, compared to variant 5L, resulting in an isoform (4L) that is shorter than isoform 5L.
      Source sequence(s)
      AC245748, AY358129, EU008600, EU008602
      Consensus CDS
      CCDS74391.1
      UniProtKB/Swiss-Prot
      Q6UY09
      UniProtKB/TrEMBL
      A0A087WZX4, A7LFK7, A7LFK9
      Related
      ENSP00000482943.1, ENST00000614577.4
      Conserved Domains (4) summary
      smart00410
      Location:175247
      IG_like; Immunoglobulin like
      pfam13895
      Location:175247
      Ig_2; Immunoglobulin domain
      pfam16821
      Location:379434
      C_Hendra; C protein from hendra and measles viruses
      cl11960
      Location:266343
      Ig; Immunoglobulin domain
    4. NM_001102600.3NP_001096070.2  carcinoembryonic antigen-related cell adhesion molecule 20 isoform 5S precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5S) lacks an alternate in-frame exon in the 3' coding region, compared to variant 5L, resulting in an isoform (5S) that is shorter than isoform 5L.
      Source sequence(s)
      AC245748, AY358129, EU008600, EU008603
      Consensus CDS
      CCDS74392.1
      UniProtKB/Swiss-Prot
      Q6UY09
      UniProtKB/TrEMBL
      A0A087X155, A7LFK7, A7LFL0
      Related
      ENSP00000483912.1, ENST00000611497.4
      Conserved Domains (4) summary
      smart00410
      Location:361433
      IG_like; Immunoglobulin like
      pfam13895
      Location:369435
      Ig_2; Immunoglobulin domain
      pfam16821
      Location:472528
      C_Hendra; C protein from hendra and measles viruses
      cl11960
      Location:266343
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

      Range
      44501309..44530101 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024451345.1XP_024307113.1  carcinoembryonic antigen-related cell adhesion molecule 20 isoform X2

      Related
      ENSP00000480940.1, ENST00000621342.4
      Conserved Domains (2) summary
      pfam13927
      Location:388447
      Ig_3; Immunoglobulin domain
      cl11960
      Location:293370
      Ig; Immunoglobulin domain
    2. XM_011526430.2XP_011524732.1  carcinoembryonic antigen-related cell adhesion molecule 20 isoform X3

      Conserved Domains (4) summary
      smart00410
      Location:388460
      IG_like; Immunoglobulin like
      pfam13895
      Location:396462
      Ig_2; Immunoglobulin domain
      pfam16821
      Location:499555
      C_Hendra; C protein from hendra and measles viruses
      cl11960
      Location:293370
      Ig; Immunoglobulin domain
    3. XM_011526429.2XP_011524731.1  carcinoembryonic antigen-related cell adhesion molecule 20 isoform X1

      Conserved Domains (4) summary
      smart00410
      Location:388460
      IG_like; Immunoglobulin like
      pfam13895
      Location:396462
      Ig_2; Immunoglobulin domain
      pfam16821
      Location:499554
      C_Hendra; C protein from hendra and measles viruses
      cl11960
      Location:293370
      Ig; Immunoglobulin domain
    4. XM_011526432.2XP_011524734.1  carcinoembryonic antigen-related cell adhesion molecule 20 isoform X5

      Conserved Domains (4) summary
      smart00410
      Location:107179
      IG_like; Immunoglobulin like
      pfam13895
      Location:115181
      Ig_2; Immunoglobulin domain
      pfam16821
      Location:218273
      C_Hendra; C protein from hendra and measles viruses
      cl11960
      Location:1289
      Ig; Immunoglobulin domain
    5. XM_011526431.2XP_011524733.1  carcinoembryonic antigen-related cell adhesion molecule 20 isoform X4

      Conserved Domains (4) summary
      smart00410
      Location:388460
      IG_like; Immunoglobulin like
      pfam13895
      Location:396462
      Ig_2; Immunoglobulin domain
      pfam16821
      Location:499554
      C_Hendra; C protein from hendra and measles viruses
      cl11960
      Location:293370
      Ig; Immunoglobulin domain

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_198444.1: Suppressed sequence

      Description
      NM_198444.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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