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    Cd9 CD9 antigen [ Mus musculus (house mouse) ]

    Gene ID: 12527, updated on 12-May-2024

    Summary

    Official Symbol
    Cd9provided by MGI
    Official Full Name
    CD9 antigenprovided by MGI
    Primary source
    MGI:MGI:88348
    See related
    Ensembl:ENSMUSG00000030342 AllianceGenome:MGI:88348
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tspan29
    Summary
    Enables integrin binding activity. Involved in several processes, including myoblast fusion involved in skeletal muscle regeneration; paranodal junction assembly; and single fertilization. Acts upstream of or within negative regulation of cell population proliferation. Located in external side of plasma membrane and extracellular exosome. Is expressed in several structures, including alimentary system; axial skeleton; nervous system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in prostate adenocarcinoma. Orthologous to human CD9 (CD9 molecule). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in bladder adult (RPKM 275.6), placenta adult (RPKM 192.8) and 24 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cd9 in Genome Data Viewer
    Location:
    6 F3; 6 59.32 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (125437229..125471723, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (125460266..125494760, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene pleckstrin homology domain containing, family G (with RhoGef domain) member 6 Neighboring gene predicted gene, 52918 Neighboring gene STARR-seq mESC enhancer starr_17342 Neighboring gene STARR-positive B cell enhancer ABC_E10410 Neighboring gene STARR-seq mESC enhancer starr_17349 Neighboring gene STARR-seq mESC enhancer starr_17355 Neighboring gene predicted gene, 32673 Neighboring gene STARR-positive B cell enhancer ABC_E8130 Neighboring gene STARR-seq mESC enhancer starr_17366 Neighboring gene predicted gene 28809 Neighboring gene STARR-seq mESC enhancer starr_17369 Neighboring gene predicted gene, 26728 Neighboring gene predicted gene, 33144 Neighboring gene STARR-positive B cell enhancer ABC_E2804 Neighboring gene STARR-seq mESC enhancer starr_17384 Neighboring gene Von Willebrand factor

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables integrin binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables integrin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    located_in external side of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in extracellular exosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
    PubMed 
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007657.4NP_031683.1  CD9 antigen

      See identical proteins and their annotated locations for NP_031683.1

      Status: VALIDATED

      Source sequence(s)
      AK002251, BC070474
      Consensus CDS
      CCDS20551.1
      UniProtKB/Swiss-Prot
      P40240, Q3U9W0
      Related
      ENSMUSP00000032492.9, ENSMUST00000032492.9
      Conserved Domains (2) summary
      cd03152
      Location:109191
      CD9_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD9 family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans ...
      pfam00335
      Location:9219
      Tetraspannin; Tetraspanin family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      125437229..125471723 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)