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    GTSF1 gametocyte specific factor 1 [ Homo sapiens (human) ]

    Gene ID: 121355, updated on 23-Sep-2022

    Summary

    Official Symbol
    GTSF1provided by HGNC
    Official Full Name
    gametocyte specific factor 1provided by HGNC
    Primary source
    HGNC:HGNC:26565
    See related
    Ensembl:ENSG00000170627 MIM:617484; AllianceGenome:HGNC:26565
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    Cue110; FAM112B
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in cell differentiation and spermatogenesis. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis (RPKM 49.6) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See GTSF1 in Genome Data Viewer
    Location:
    12q13.13
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    110 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (54455957..54473602, complement)
    110 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (54422534..54440179, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (54849741..54867386, complement)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene GPR84, ZNF385A, ITGA5 and GTSF1 antisense RNA 1 Neighboring gene zinc finger protein 385A Neighboring gene integrin subunit alpha 5 Neighboring gene NCK associated protein 1 like Neighboring gene phosphodiesterase 1B

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ32942

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables tRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    gametocyte-specific factor 1
    Names
    family with sequence similarity 112, member B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144594.3NP_653195.2  gametocyte-specific factor 1

      See identical proteins and their annotated locations for NP_653195.2

      Status: VALIDATED

      Source sequence(s)
      AK098819, BE503352
      Consensus CDS
      CCDS8881.1
      UniProtKB/Swiss-Prot
      Q8N778, Q8WW33
      UniProtKB/TrEMBL
      A0A024RB57
      Related
      ENSP00000304185.5, ENST00000305879.8
      Conserved Domains (1) summary
      pfam05253
      Location:1538
      zf-U11-48K; U11-48K-like CHHC zinc finger

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

      Range
      54455957..54473602 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017018800.3XP_016874289.1  gametocyte-specific factor 1 isoform X1

      UniProtKB/Swiss-Prot
      Q8N778, Q8WW33
      UniProtKB/TrEMBL
      A0A024RB57
      Conserved Domains (1) summary
      pfam05253
      Location:1538
      zf-U11-48K; U11-48K-like CHHC zinc finger
    2. XM_024448834.2XP_024304602.1  gametocyte-specific factor 1 isoform X1

      UniProtKB/Swiss-Prot
      Q8N778
      UniProtKB/TrEMBL
      A0A024RB57
      Related
      ENSP00000446485.1, ENST00000552397.5
      Conserved Domains (1) summary
      pfam05253
      Location:1538
      zf-U11-48K; U11-48K-like CHHC zinc finger

    RNA

    1. XR_007063048.1 RNA Sequence

    2. XR_007063047.1 RNA Sequence

    3. XR_007063049.1 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060936.1 Alternate T2T-CHM13v2.0

      Range
      54422534..54440179 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)