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    PARK7 Parkinsonism associated deglycase [ Homo sapiens (human) ]

    Gene ID: 11315, updated on 28-Nov-2021

    Summary

    Official Symbol
    PARK7provided by HGNC
    Official Full Name
    Parkinsonism associated deglycaseprovided by HGNC
    Primary source
    HGNC:HGNC:16369
    See related
    Ensembl:ENSG00000116288 MIM:602533
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    DJ1; DJ-1; GATD2; HEL-S-67p
    Summary
    The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
    Expression
    Ubiquitous expression in adrenal (RPKM 125.5), thyroid (RPKM 111.2) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See PARK7 in Genome Data Viewer
    Location:
    1p36.23
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (7961711..7985505)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (8021771..8045565)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene urotensin 2 Neighboring gene TNF receptor superfamily member 9 Neighboring gene tRNA-undetermined (NNN) 4-1 Neighboring gene Sharpr-MPRA regulatory region 3725 Neighboring gene Sharpr-MPRA regulatory region 3772

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    Associated conditions

    Description Tests
    Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
    GeneReviews: Not available
    Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.
    GeneReviews: Not available
    Multiple common variants for celiac disease influencing immune gene expression.
    GeneReviews: Not available
    Parkinson disease 7
    MedGen: C1853445 OMIM: 606324 GeneReviews: Parkinson Disease Overview
    Compare labs
    Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
    GeneReviews: Not available

    HIV-1 interactions

    Protein interactions

    Protein Gene Interaction Pubs
    Tat tat HIV-1 Tat upregulates the expression of parkinson protein 7 (PARK7; DJ1) in Jurkat cells PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ27376, FLJ34360, FLJ92274

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA-binding transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables L-dopa decarboxylase activator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables androgen receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables cadherin binding HDA PubMed 
    enables copper ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT enables core promoter sequence-specific DNA binding IC
    Inferred by Curator
    more info
    PubMed 
    enables cupric ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables cuprous ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables cytokine binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    NOT enables double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables enzyme binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables glyoxalase (glycolic acid-forming) activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables mercury ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables oxidoreductase activity, acting on peroxide as acceptor IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables oxygen sensor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables peroxiredoxin activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein deglycase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    NOT enables protein deglycase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein deglycase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein-containing complex binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables scaffold protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables signaling receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    NOT enables single-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables small protein activating enzyme binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables superoxide dismutase copper chaperone activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables transcription coactivator activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    enables transcription coactivator activity TAS
    Traceable Author Statement
    more info
    PubMed 
    enables tyrosine 3-monooxygenase activator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables ubiquitin-like protein conjugating enzyme binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables ubiquitin-specific protease binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in DNA repair IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in Ras protein signal transduction TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in activation of protein kinase B activity IC
    Inferred by Curator
    more info
    PubMed 
    involved_in adult locomotory behavior IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cellular detoxification of aldehyde IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cellular detoxification of methylglyoxal IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cellular oxidant detoxification IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cellular response to glyoxal IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cellular response to hydrogen peroxide IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cellular response to oxidative stress IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cellular response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in detection of oxidative stress IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in detoxification of copper ion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in detoxification of mercury ion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in dopamine uptake involved in synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in glucose homeostasis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in glutathione deglycation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in glycolate biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in glyoxal catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in glyoxal metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in guanine deglycation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in guanine deglycation, glyoxal removal IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in guanine deglycation, glyoxal removal IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in guanine deglycation, methylglyoxal removal IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in histone modification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in hydrogen peroxide metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in insulin secretion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in lactate biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in membrane depolarization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in membrane hyperpolarization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in methylglyoxal catabolic process to lactate IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT involved_in methylglyoxal metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in methylglyoxal metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in mitochondrion organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of TRAIL-activated apoptotic signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of apoptotic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of cell death IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of death-inducing signaling complex assembly IC
    Inferred by Curator
    more info
    PubMed 
    involved_in negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of extrinsic apoptotic signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of gene expression IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of hydrogen peroxide-induced cell death IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of hydrogen peroxide-induced neuron death IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of neuron apoptotic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of neuron death IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of oxidative stress-induced cell death IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of proteasomal ubiquitin-dependent protein catabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of protein K48-linked deubiquitination IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of protein acetylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of protein binding IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of protein binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of protein export from nucleus IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of protein kinase activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of protein phosphorylation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of protein sumoylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of protein ubiquitination IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of reactive oxygen species biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of ubiquitin-protein transferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of ubiquitin-specific protease activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in peptidyl-arginine deglycation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in peptidyl-arginine deglycation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in peptidyl-cysteine deglycation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in peptidyl-lysine deglycation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of DNA-binding transcription factor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of DNA-binding transcription factor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in positive regulation of L-dopa biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of L-dopa decarboxylase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of NAD(P)H oxidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of acute inflammatory response to antigenic stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of androgen receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of autophagy of mitochondrion NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in positive regulation of dopamine biosynthetic process IC
    Inferred by Curator
    more info
    PubMed 
    involved_in positive regulation of dopamine biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of gene expression TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in positive regulation of interleukin-8 production IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of mitochondrial electron transport, NADH to ubiquinone IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of oxidative phosphorylation uncoupler activity IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of peptidyl-serine phosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of protein kinase B signaling IC
    Inferred by Curator
    more info
    PubMed 
    involved_in positive regulation of protein localization to nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of protein localization to nucleus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of protein-containing complex assembly IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of pyrroline-5-carboxylate reductase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of reactive oxygen species biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of superoxide dismutase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of transcription regulatory region DNA binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of tyrosine 3-monooxygenase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein deglycation, glyoxal removal IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein deglycation, glyoxal removal IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT involved_in protein deglycation, methylglyoxal removal IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein deglycation, methylglyoxal removal IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein deglycation, methylglyoxal removal IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    NOT involved_in protein deglycosylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein deglycosylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein deglycosylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein stabilization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein stabilization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    NOT involved_in regulation of TRAIL production IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of androgen receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of histone acetylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of histone ubiquitination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of inflammatory response ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of mitochondrial membrane potential IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of neuron apoptotic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of supramolecular fiber organization TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in single fertilization IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in PML body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in adherens junction HDA PubMed 
    located_in axon ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cell body IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in extracellular exosome HDA PubMed 
    located_in membrane raft IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial intermembrane space IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    located_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in presynapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Parkinson disease protein 7
    Names
    Parkinson disease (autosomal recessive, early onset) 7
    epididymis secretory sperm binding protein Li 67p
    maillard deglycase
    oncogene DJ1
    parkinson protein 7
    protein DJ-1
    protein deglycase DJ-1
    protein/nucleic acid deglycase DJ-1
    NP_001116849.1
    NP_009193.2
    XP_005263481.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_008271.1 RefSeqGene

      Range
      5058..28852
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001123377.2NP_001116849.1  Parkinson disease protein 7

      See identical proteins and their annotated locations for NP_001116849.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) represents the shorter transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK312000, AL034417, D61380
      Consensus CDS
      CCDS93.1
      UniProtKB/Swiss-Prot
      Q99497
      UniProtKB/TrEMBL
      V9HWC2
      Related
      ENSP00000418770.1, ENST00000493678.5
      Conserved Domains (1) summary
      TIGR01383
      Location:5184
      not_thiJ; DJ-1 family protein
    2. NM_007262.5NP_009193.2  Parkinson disease protein 7

      See identical proteins and their annotated locations for NP_009193.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK312000, AL034417, BC008188, BP248330, D61380
      Consensus CDS
      CCDS93.1
      UniProtKB/Swiss-Prot
      Q99497
      UniProtKB/TrEMBL
      V9HWC2
      Related
      ENSP00000340278.5, ENST00000338639.10
      Conserved Domains (1) summary
      TIGR01383
      Location:5184
      not_thiJ; DJ-1 family protein

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

      Range
      7961711..7985505
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005263424.3XP_005263481.1  Parkinson disease protein 7 isoform X1

      See identical proteins and their annotated locations for XP_005263481.1

      UniProtKB/Swiss-Prot
      Q99497
      UniProtKB/TrEMBL
      V9HWC2
      Related
      ENSP00000366711.1, ENST00000377491.5
      Conserved Domains (1) summary
      TIGR01383
      Location:5184
      not_thiJ; DJ-1 family protein
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