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    JTB jumping translocation breakpoint [ Homo sapiens (human) ]

    Gene ID: 10899, updated on 15-Jun-2019

    Summary

    Official Symbol
    JTBprovided by HGNC
    Official Full Name
    jumping translocation breakpointprovided by HGNC
    Primary source
    HGNC:HGNC:6201
    See related
    Ensembl:ENSG00000143543 MIM:604671
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PAR; hJT; HJTB; HSPC222
    Expression
    Ubiquitous expression in colon (RPKM 43.4), stomach (RPKM 38.7) and 25 other tissues See more
    Orthologs

    Genomic context

    See JTB in Genome Data Viewer
    Location:
    1q21.3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 1 NC_000001.11 (153974269..153977975, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (153946745..153951096, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene CREB regulated transcription coactivator 2 Neighboring gene solute carrier family 39 member 1 Neighboring gene microRNA 6737 Neighboring gene cAMP responsive element binding protein 3 like 4 Neighboring gene RAB13, member RAS oncogene family Neighboring gene ribosomal protein S27

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein kinase binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitotic cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitotic cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of protein kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    colocalizes_with centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with centrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of plasma membrane TAS
    Traceable Author Statement
    more info
    PubMed 
    membrane TAS
    Traceable Author Statement
    more info
    PubMed 
    midbody IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    midbody IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with spindle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with spindle IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    protein JTB
    Names
    jumping translocation breakpoint protein
    prostate androgen-regulated protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_006694.4NP_006685.1  protein JTB precursor

      See identical proteins and their annotated locations for NP_006685.1

      Status: VALIDATED

      Source sequence(s)
      AL358472
      Consensus CDS
      CCDS1057.1
      UniProtKB/Swiss-Prot
      O76095
      Related
      ENSP00000271843.4, ENST00000271843.9
      Conserved Domains (1) summary
      pfam05439
      Location:37143
      JTB; Jumping translocation breakpoint protein (JTB)

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

      Range
      153974269..153977674 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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