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    PNMA2 PNMA family member 2 [ Homo sapiens (human) ]

    Gene ID: 10687, updated on 15-Jun-2019

    Summary

    Official Symbol
    PNMA2provided by HGNC
    Official Full Name
    PNMA family member 2provided by HGNC
    Primary source
    HGNC:HGNC:9159
    See related
    Ensembl:ENSG00000240694 MIM:603970
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MA2; MM2; RGAG2
    Expression
    Biased expression in brain (RPKM 63.2), adrenal (RPKM 6.1) and 1 other tissue See more
    Orthologs

    Genomic context

    See PNMA2 in Genome Data Viewer
    Location:
    8p21.2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 8 NC_000008.11 (26504680..26513967, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (26362196..26371608, complement)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene dnaJ homolog subfamily B member 6-like Neighboring gene uncharacterized LOC105379337 Neighboring gene dihydropyrimidinase like 2 Neighboring gene proteasome activator subunit 2 pseudogene 5 Neighboring gene adrenoceptor alpha 1A Neighboring gene ribosomal protein lateral stalk subunit P1 pseudogene 9

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA0883

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    positive regulation of apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    nucleolus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    paraneoplastic antigen Ma2
    Names
    40 kDa neuronal protein
    onconeuronal antigen MA2
    paraneoplastic Ma antigen 2
    paraneoplastic neuronal antigen MM2
    retrotransposon gag domain containing 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007257.6NP_009188.1  paraneoplastic antigen Ma2

      See identical proteins and their annotated locations for NP_009188.1

      Status: VALIDATED

      Source sequence(s)
      AB020690, BC036489, BC047515, DA779744
      Consensus CDS
      CCDS34868.1
      UniProtKB/Swiss-Prot
      Q9UL42
      UniProtKB/TrEMBL
      Q5U5Z3
      Related
      ENSP00000429344.1, ENST00000522362.7
      Conserved Domains (1) summary
      pfam14893
      Location:1327
      PNMA; PNMA

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

      Range
      26504695..26513872 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011544365.3XP_011542667.1  paraneoplastic antigen Ma2 isoform X1

      See identical proteins and their annotated locations for XP_011542667.1

      UniProtKB/Swiss-Prot
      Q9UL42
      Conserved Domains (1) summary
      pfam14893
      Location:1327
      PNMA; PNMA
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