U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    CDR2 cerebellar degeneration related protein 2 [ Homo sapiens (human) ]

    Gene ID: 1039, updated on 5-Mar-2024

    Summary

    Official Symbol
    CDR2provided by HGNC
    Official Full Name
    cerebellar degeneration related protein 2provided by HGNC
    Primary source
    HGNC:HGNC:1799
    See related
    Ensembl:ENSG00000140743 MIM:117340; AllianceGenome:HGNC:1799
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    Yo; CDR62
    Summary
    Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in testis (RPKM 38.3), thyroid (RPKM 28.3) and 24 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See CDR2 in Genome Data Viewer
    Location:
    16p12.2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (22345936..22374619, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (21842595..21871275)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (22357257..22385940, complement)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:22308474-22309018 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10570 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7267 Neighboring gene tRNA-Leu (anticodon AAG) 2-4 Neighboring gene Sharpr-MPRA regulatory region 3906 Neighboring gene RNA polymerase III subunit E Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:22333033-22333580 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:22333581-22334130 Neighboring gene uncharacterized LOC124903664 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:22358198-22358698 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10571 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7268 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7269 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10572 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10573 Neighboring gene CDR2 divergent transcript Neighboring gene major facilitator superfamily domain containing 13B (pseudogene)

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    cerebellar degeneration-related protein 2
    Names
    Yo paraneoplastic antigen
    cerebellar degeneration-related protein 2, 62kDa
    major Yo paraneoplastic antigen
    paraneoplastic cerebellar degeneration-associated antigen

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001802.2NP_001793.1  cerebellar degeneration-related protein 2

      See identical proteins and their annotated locations for NP_001793.1

      Status: VALIDATED

      Source sequence(s)
      AC092338, BC017503, BG386156, BG750955, BM714067, CB990819, M63256
      Consensus CDS
      CCDS32404.1
      UniProtKB/Swiss-Prot
      A8K8A8, Q01850, Q13977
      Related
      ENSP00000268383.2, ENST00000268383.7
      Conserved Domains (1) summary
      TIGR02168
      Location:8263
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

      Range
      22345936..22374619 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024450143.2XP_024305911.1  cerebellar degeneration-related protein 2 isoform X1

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_017852933.1 Reference GRCh38.p14 PATCHES

      Range
      730420..759098
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054332139.1XP_054188114.1  cerebellar degeneration-related protein 2 isoform X1

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060940.1 Alternate T2T-CHM13v2.0

      Range
      21842595..21871275
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054379386.1XP_054235361.1  cerebellar degeneration-related protein 2 isoform X1