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    NPY4R2 neuropeptide Y receptor Y4-2 [ Homo sapiens (human) ]

    Gene ID: 100996758, updated on 19-Jun-2019

    Summary

    Official Symbol
    NPY4R2provided by HGNC
    Official Full Name
    neuropeptide Y receptor Y4-2provided by HGNC
    Primary source
    HGNC:HGNC:52383
    See related
    Ensembl:ENSG00000264717
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PP1; NPY4R; PPYR1; NPY4-R; CH17-360D5.1
    Expression
    Biased expression in colon (RPKM 2.8), skin (RPKM 1.5) and 7 other tissues See more
    Orthologs

    Genomic context

    See NPY4R2 in Genome Data Viewer
    Location:
    10q11.22
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (47913999..47926069)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 (PATCHES) NW_003871068.1 (2110730..2113565)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene annexin A8 Neighboring gene uncharacterized LOC102724603 Neighboring gene shieldin complex subunit 2 pseudogene 3 Neighboring gene uncharacterized LOC102724593 Neighboring gene synaptotagmin-15 Neighboring gene Sharpr-MPRA regulatory regions 2784 and 8617 duplicate 2 Neighboring gene family with sequence similarity 25 member C Neighboring gene ArfGAP with GTPase domain, ankyrin repeat and PH domain 12, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    G protein-coupled receptor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    neuropeptide Y receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    pancreatic polypeptide receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    pancreatic polypeptide receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    peptide hormone binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    G protein-coupled receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    G protein-coupled receptor signaling pathway TAS
    Traceable Author Statement
    more info
     
    neuropeptide signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of plasma membrane TAS
    Traceable Author Statement
    more info
    PubMed 
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    neuropeptide Y receptor type 4-2
    Names
    Neuropeptide Y receptor type 4
    Neuropeptide Y receptor type 4-2
    Pancreatic polypeptide receptor 1
    neuropeptide Y receptor Y42

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001278795.2NP_001265724.1  neuropeptide Y receptor type 4-2

      See identical proteins and their annotated locations for NP_001265724.1

      Status: VALIDATED

      Source sequence(s)
      AC245041
      Consensus CDS
      CCDS81459.1
      UniProtKB/Swiss-Prot
      P50391
      Conserved Domains (1) summary
      cd15397
      Location:42333
      7tmA_NPY4R; neuropeptide Y receptor type 4, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

      Range
      47913999..47926069
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017015464.1XP_016870953.1  neuropeptide Y receptor type 4-2 isoform X1

      UniProtKB/Swiss-Prot
      P50391
      Conserved Domains (1) summary
      cd15397
      Location:42333
      7tmA_NPY4R; neuropeptide Y receptor type 4, member of the class A family of seven-transmembrane G protein-coupled receptors
    2. XM_011539115.2XP_011537417.1  neuropeptide Y receptor type 4-2 isoform X1

      See identical proteins and their annotated locations for XP_011537417.1

      UniProtKB/Swiss-Prot
      P50391
      Conserved Domains (1) summary
      cd15397
      Location:42333
      7tmA_NPY4R; neuropeptide Y receptor type 4, member of the class A family of seven-transmembrane G protein-coupled receptors
    3. XM_005277644.3XP_005277701.1  neuropeptide Y receptor type 4-2 isoform X1

      See identical proteins and their annotated locations for XP_005277701.1

      UniProtKB/Swiss-Prot
      P50391
      Related
      ENSP00000490174.1, ENST00000576178.6
      Conserved Domains (1) summary
      cd15397
      Location:42333
      7tmA_NPY4R; neuropeptide Y receptor type 4, member of the class A family of seven-transmembrane G protein-coupled receptors
    4. XM_006717545.3XP_006717608.1  neuropeptide Y receptor type 4-2 isoform X1

      See identical proteins and their annotated locations for XP_006717608.1

      UniProtKB/Swiss-Prot
      P50391
      Related
      ENSP00000489924.1, ENST00000613306.1
      Conserved Domains (1) summary
      cd15397
      Location:42333
      7tmA_NPY4R; neuropeptide Y receptor type 4, member of the class A family of seven-transmembrane G protein-coupled receptors
    5. XM_017015463.1XP_016870952.1  neuropeptide Y receptor type 4-2 isoform X1

      UniProtKB/Swiss-Prot
      P50391
      Conserved Domains (1) summary
      cd15397
      Location:42333
      7tmA_NPY4R; neuropeptide Y receptor type 4, member of the class A family of seven-transmembrane G protein-coupled receptors

    Reference GRCh38.p13 PATCHES

    Genomic

    1. NW_021160001.1 Reference GRCh38.p13 PATCHES

      Range
      135310..141659
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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