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    KRTAP4-7 keratin associated protein 4-7 [ Homo sapiens (human) ]

    Gene ID: 100132476, updated on 12-Aug-2021

    Summary

    Official Symbol
    KRTAP4-7provided by HGNC
    Official Full Name
    keratin associated protein 4-7provided by HGNC
    Primary source
    HGNC:HGNC:18898
    See related
    Ensembl:ENSG00000240871
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    KAP4.7; KRTAP4.7
    Summary
    This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the ultrahigh sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Mar 2009]
    Orthologs
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    Genomic context

    See KRTAP4-7 in Genome Data Viewer
    Location:
    17q21.2
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    109.20210514 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (41084207..41085144)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (39240459..39241396)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene keratin associated protein 2-4 Neighboring gene keratin associated protein 2-5, pseudogene Neighboring gene keratin associated protein 4-8 Neighboring gene keratin associated protein 4-16

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC161699, MGC161701

    General protein information

    Preferred Names
    putative keratin-associated protein 4-X
    Names
    Ultrahigh sulfur keratin-associated protein 4.7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_033061.4NP_149050.3  putative keratin-associated protein 4-X

      Status: VALIDATED

      Source sequence(s)
      AC100808
      Consensus CDS
      CCDS45673.1
      Related
      ENSP00000375236.4, ENST00000391417.5
      Conserved Domains (2) summary
      pfam01500
      Location:3154
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam13885
      Location:4488
      Keratin_B2_2; Keratin, high sulfur B2 protein

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

      Range
      41084207..41085144
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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