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    TOP DNA topoisomerase [ Emiliania huxleyi CCMP1516 ]

    Gene ID: 17266155, updated on 20-Feb-2025
    Gene symbol
    TOP
    Gene description
    DNA topoisomerase
    Locus tag
    EMIHUDRAFT_310561
    Gene type
    protein coding
    RNA name
    DNA topoisomerase
    RefSeq status
    PROVISIONAL
    Organism
    Emiliania huxleyi CCMP1516 (strain: CCMP1516)
    Lineage
    Eukaryota; Haptophyceae; Isochrysidales; Noelaerhabdaceae; Emiliania
    NEW
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    See TOP in Genome Data Viewer
    Location:
    chromosome: Unknown
    Exon count:
    3

    NW_005199363.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene putative inorganic phosphate transporter Neighboring gene hypothetical protein

    Genomic Sequence:
    NW_005199363.1

    Go to nucleotide: Graphics FASTA GenBank

    Related articles in PubMed

    1. Pan genome of the phytoplankton Emiliania underpins its global distribution. Read BA, et al. Nature, 2013 Jul 11. PMID 23760476
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA topological change IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Names
    DNA topoisomerase
    XP_005773037.1
    • Chromatin unwinding and binding

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NW_005199363.1 Reference assembly

      Range
      796441..799215 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005772980.1 → XP_005773037.1  DNA topoisomerase [Emiliania huxleyi CCMP1516]

      See identical proteins and their annotated locations for XP_005773037.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0D3JAS3, A0A7S3TYZ9, R1CCZ8
      Conserved Domains (4) summary
      PRK05560
      Location:1 → 820
      PRK05560; DNA gyrase subunit A; Validated
      cd00187
      Location:14 → 464
      TOP4c; DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA ...
      pfam03989
      Location:648 → 697
      DNA_gyraseA_C; DNA gyrase C-terminal domain, beta-propeller
      sd00041
      Location:494 → 541
      GyrA-ParC_C; GyrA_CTD repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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