rna RNase I [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Official Symbol: rna
Official Full Name: RNase I
Primary source: ECOCYC:EG10856
Locus tag: b0611
See related: ASAP:ABE-0002107
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK0604; rnsA
Summary: Ribonuclease I (RNase I) is an endonuclease that cleaves phosphodiester bonds in RNA, yielding nucleoside 3'-phosphates and 3'-phosphooligonucleotides . [More information is available at EcoCyc: EG10856].
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NC_000913.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

E. coli RNase I exhibits a strong Ca2+-dependent inherent double-stranded RNase activity.
Title: E. coli RNase I exhibits a strong Ca2+-dependent inherent double-stranded RNase activity.
Substantiating prior suggestions that MRE600 lacks RNase I activity, the RNase I-encoding gene, rna, contains a single premature stop codon early in its open-reading frame.
Title: Genome Sequence and Analysis of Escherichia coli MRE600, a Colicinogenic, Nonmotile Strain that Lacks RNase I and the Type I Methyltransferase, EcoKI.
N-terminus verified by Edman degradation on mature peptide
Title: Cloning and sequencing the gene encoding Escherichia coli ribonuclease I: exact physical mapping using the genome library.

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Function	Evidence Code	Pubs
enables Enterobacter ribonuclease activity	IEA Inferred from Electronic Annotation more info
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables ribonuclease T2 activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in RNA catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in RNA catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within RNA catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in outer membrane-bounded periplasmic space	IDA Inferred from Direct Assay more info	PubMed
located_in periplasmic space	IEA Inferred from Electronic Annotation more info