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    Cd6 Cd6 molecule [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25752, updated on 17-Sep-2016
    Official Symbol
    Cd6provided by RGD
    Official Full Name
    Cd6 moleculeprovided by RGD
    Primary source
    RGD:2312
    See related
    Ensembl:ENSRNOG00000020884
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
    Also known as
    OX52
    Summary
    cell surface molecule found on T lymphocytes that may regulate CD5 tyrosine phosphorylation; associates with CD5, Lck, Fyn, ZAP-70 and Itk [RGD, Feb 2006]
    Orthologs
    Location:
    1q41
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (226848399..226887259, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (233913073..233951869, complement)

    Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene pepsin F-like Neighboring gene VPS37C, ESCRT-I subunit Neighboring gene Cd5 molecule Neighboring gene solute carrier family 15 member 3 Neighboring gene transmembrane protein 132A Neighboring gene transmembrane protein 109

    • Cell adhesion molecules (CAMs), organism-specific biosystem (from KEGG)
      Cell adhesion molecules (CAMs), organism-specific biosystemCell adhesion molecules are (glyco)proteins expressed on the cell surface and play a critical role in a wide array of biologic processes that include hemostasis, the immune response, inflammation, em...
    • Cell adhesion molecules (CAMs), conserved biosystem (from KEGG)
      Cell adhesion molecules (CAMs), conserved biosystemCell adhesion molecules are (glyco)proteins expressed on the cell surface and play a critical role in a wide array of biologic processes that include hemostasis, the immune response, inflammation, em...

    Markers

    Homology

    Clone Names

    • MGC108551

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    glycoprotein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    lipopolysaccharide binding ISO
    Inferred from Sequence Orthology
    more info
     
    lipoteichoic acid binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein kinase binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    scavenger receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    colocalizes_with T cell receptor complex ISO
    Inferred from Sequence Orthology
    more info
     
    immunological synapse ISO
    Inferred from Sequence Orthology
    more info
     
    intrinsic component of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    spanning component of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    T-cell differentiation antigen CD6
    Names
    CD6 antigen, Tp120

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175577.3NP_783167.2  T-cell differentiation antigen CD6 precursor

      See identical proteins and their annotated locations for NP_783167.2

      Status: VALIDATED

      Source sequence(s)
      AF488727, BC089767, CO559874
      UniProtKB/TrEMBL
      G3V8U0, Q5FVU4, Q812A4
      Related
      ENSRNOP00000028347, ENSRNOT00000028347
      Conserved Domains (2) summary
      smart00202
      Location:160259
      SR; Scavenger receptor Cys-rich
      pfam00530
      Location:165259
      SRCR; Scavenger receptor cysteine-rich domain

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

      Range
      226848399..226887259 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017588836.1XP_017444325.1  

      Related
      ENSRNOP00000051694, ENSRNOT00000054809
    2. XM_008760218.2XP_008758440.1  

      Conserved Domains (2) summary
      smart00202
      Location:160259
      SR; Scavenger receptor Cys-rich
      pfam00530
      Location:165259
      SRCR; Scavenger receptor cysteine-rich domain
    3. XM_006231021.3XP_006231083.1  

      Conserved Domains (2) summary
      smart00202
      Location:160259
      SR; Scavenger receptor Cys-rich
      pfam00530
      Location:165259
      SRCR; Scavenger receptor cysteine-rich domain
    4. XM_008760219.2XP_008758441.1  

      Conserved Domains (2) summary
      smart00202
      Location:160259
      SR; Scavenger receptor Cys-rich
      pfam00530
      Location:165259
      SRCR; Scavenger receptor cysteine-rich domain
    5. XM_017588835.1XP_017444324.1  

    6. XM_017588834.1XP_017444323.1  

    Alternate Rn_Celera

    Genomic

    1. AC_000069.1 Alternate Rn_Celera

      Range
      204934769..204973456 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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