U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    ZNF232 zinc finger protein 232 [ Homo sapiens (human) ]

    Gene ID: 7775, updated on 19-Sep-2024

    Summary

    Official Symbol
    ZNF232provided by HGNC
    Official Full Name
    zinc finger protein 232provided by HGNC
    Primary source
    HGNC:HGNC:13026
    See related
    Ensembl:ENSG00000167840 MIM:616463; AllianceGenome:HGNC:13026
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ZSCAN11
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in ovary (RPKM 6.2), testis (RPKM 4.2) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ZNF232 in Genome Data Viewer
    Location:
    17p13.2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (5105734..5123116, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (4999106..5016496, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (5009029..5026411, complement)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:4981230-4982101 Neighboring gene ZFP3 divergent transcript Neighboring gene ZFP3 zinc finger protein Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11566 Neighboring gene ZNF232 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:5033804-5034304 Neighboring gene ubiquitin specific peptidase 6 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:5040130-5040801 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:5040802-5041472 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:5042145-5042815 Neighboring gene MPRA-validated peak2704 silencer Neighboring gene zinc finger protein 594 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8065 Neighboring gene ZNF594 divergent transcript Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8066 Neighboring gene SLP adaptor and CSK interacting membrane protein Neighboring gene MPRA-validated peak2705 silencer

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
     
    located_in intracellular membrane-bounded organelle IDA
    Inferred from Direct Assay
    more info
     
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     

    General protein information

    Preferred Names
    zinc finger protein 232
    Names
    zinc finger and SCAN domain-containing protein 11

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001320952.1NP_001307881.1  zinc finger protein 232 isoform b

      Status: VALIDATED

      Source sequence(s)
      AK225622, BQ184519, BQ641476
      Consensus CDS
      CCDS82043.1
      Related
      ENSP00000461305.1, ENST00000575898.5
      Conserved Domains (6) summary
      smart00431
      Location:75188
      SCAN; leucine rich region
      COG5048
      Location:294400
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:324344
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:294316
      zf-C2H2; Zinc finger, C2H2 type
      pfam02023
      Location:75162
      SCAN; SCAN domain
      pfam13465
      Location:364389
      zf-H2C2_2; Zinc-finger double domain
    2. NM_001320953.2NP_001307882.1  zinc finger protein 232 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: Variants 3 and 4 encode the same isoform (c).
      Source sequence(s)
      AC012146
      Conserved Domains (4) summary
      smart00431
      Location:48161
      SCAN; leucine rich region
      COG5048
      Location:302382
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:306326
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:276298
      zf-C2H2; Zinc finger, C2H2 type
    3. NM_001320954.2NP_001307883.1  zinc finger protein 232 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: Variants 3 and 4 encode the same isoform (c).
      Source sequence(s)
      AC012146
      Conserved Domains (4) summary
      smart00431
      Location:48161
      SCAN; leucine rich region
      COG5048
      Location:302382
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:306326
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:276298
      zf-C2H2; Zinc finger, C2H2 type
    4. NM_001320955.1NP_001307884.1  zinc finger protein 232 isoform d

      Status: VALIDATED

      Source sequence(s)
      AC012146
      Consensus CDS
      CCDS92233.1
      UniProtKB/TrEMBL
      A0A8Q3SIR0
      Related
      ENSP00000512696.1, ENST00000696535.1
      Conserved Domains (5) summary
      COG5048
      Location:301381
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:305325
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:275297
      zf-C2H2; Zinc finger, C2H2 type
      pfam02023
      Location:75139
      SCAN; SCAN domain
      pfam13465
      Location:345370
      zf-H2C2_2; Zinc-finger double domain
    5. NM_001395550.1NP_001382479.1  zinc finger protein 232 isoform e

      Status: VALIDATED

      Source sequence(s)
      AC012146
      Conserved Domains (5) summary
      COG5048
      Location:300352
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:248268
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:218240
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:288313
      zf-H2C2_2; Zinc-finger double domain
      cl02605
      Location:2791
      SCAN; SCAN oligomerization domain
    6. NM_001395551.1NP_001382480.1  zinc finger protein 232 isoform f

      Status: VALIDATED

      Source sequence(s)
      AC012146
      Conserved Domains (4) summary
      smart00431
      Location:48161
      SCAN; leucine rich region
      COG5048
      Location:267373
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:297317
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:337362
      zf-H2C2_2; Zinc-finger double domain
    7. NM_001395552.1NP_001382481.1  zinc finger protein 232 isoform g

      Status: VALIDATED

      Source sequence(s)
      AC012146
      Conserved Domains (5) summary
      COG5048
      Location:309361
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:257277
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:227249
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:297322
      zf-H2C2_2; Zinc-finger double domain
      cl02605
      Location:2791
      SCAN; SCAN oligomerization domain
    8. NM_014519.6NP_055334.2  zinc finger protein 232 isoform a

      See identical proteins and their annotated locations for NP_055334.2

      Status: VALIDATED

      Source sequence(s)
      AC012146
      Consensus CDS
      CCDS11068.1
      UniProtKB/Swiss-Prot
      I3L4J6, Q9UNY5
      Related
      ENSP00000250076.3, ENST00000250076.8
      Conserved Domains (6) summary
      smart00431
      Location:75188
      SCAN; leucine rich region
      COG5048
      Location:303409
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:333353
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:303325
      zf-C2H2; Zinc finger, C2H2 type
      pfam02023
      Location:75162
      SCAN; SCAN domain
      pfam13465
      Location:373398
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

      Range
      5105734..5123116 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047436671.1XP_047292627.1  zinc finger protein 232 isoform X2

    2. XM_047436668.1XP_047292624.1  zinc finger protein 232 isoform X1

      UniProtKB/Swiss-Prot
      I3L4J6, Q9UNY5
    3. XM_047436674.1XP_047292630.1  zinc finger protein 232 isoform X5

    4. XM_047436669.1XP_047292625.1  zinc finger protein 232 isoform X1

      UniProtKB/Swiss-Prot
      I3L4J6, Q9UNY5
    5. XM_047436670.1XP_047292626.1  zinc finger protein 232 isoform X1

      UniProtKB/Swiss-Prot
      I3L4J6, Q9UNY5
    6. XM_047436673.1XP_047292629.1  zinc finger protein 232 isoform X4

    7. XM_047436672.1XP_047292628.1  zinc finger protein 232 isoform X3

      UniProtKB/TrEMBL
      A0A8Q3SIT7
      Related
      ENSP00000512697.1, ENST00000696536.1
    8. XM_011524006.4XP_011522308.1  zinc finger protein 232 isoform X3

      See identical proteins and their annotated locations for XP_011522308.1

      UniProtKB/TrEMBL
      A0A8Q3SIT7
      Conserved Domains (6) summary
      smart00431
      Location:27140
      SCAN; leucine rich region
      COG5048
      Location:281361
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:285305
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:255277
      zf-C2H2; Zinc finger, C2H2 type
      pfam02023
      Location:27114
      SCAN; SCAN domain
      pfam13465
      Location:325350
      zf-H2C2_2; Zinc-finger double domain

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060941.1 Alternate T2T-CHM13v2.0

      Range
      4999106..5016496 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054317081.1XP_054173056.1  zinc finger protein 232 isoform X2

    2. XM_054317078.1XP_054173053.1  zinc finger protein 232 isoform X1

      UniProtKB/Swiss-Prot
      I3L4J6, Q9UNY5
    3. XM_054317085.1XP_054173060.1  zinc finger protein 232 isoform X5

    4. XM_054317079.1XP_054173054.1  zinc finger protein 232 isoform X1

      UniProtKB/Swiss-Prot
      I3L4J6, Q9UNY5
    5. XM_054317080.1XP_054173055.1  zinc finger protein 232 isoform X1

      UniProtKB/Swiss-Prot
      I3L4J6, Q9UNY5
    6. XM_054317084.1XP_054173059.1  zinc finger protein 232 isoform X4

    7. XM_054317082.1XP_054173057.1  zinc finger protein 232 isoform X3

      UniProtKB/TrEMBL
      A0A8Q3SIT7
    8. XM_054317083.1XP_054173058.1  zinc finger protein 232 isoform X3

      UniProtKB/TrEMBL
      A0A8Q3SIT7