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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_012771.2 RefSeqGene
- Range
-
5094..104742
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001286074.2 → NP_001273003.2 transcription initiation factor TFIID subunit 1 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3, also known as neuron specific isoform or N-TAF1).
- Source sequence(s)
-
AB300418, AL590763
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
- Related
- ENSP00000276072.5, ENST00000276072.9
- Conserved Domains (4) summary
-
- cd05511
Location:1508 → 1620
- Bromo_TFIID; Bromodomain, TFIID-like subfamily. Human TAFII250 (or TAF250) is the largest subunit of TFIID, a large multi-domain complex, which initiates the assembly of the transcription machinery. TAFII250 contains two bromodomains that specifically bind to ...
- pfam09247
Location:8 → 66
- TBP-binding; TATA box-binding protein binding
- pfam12157
Location:566 → 1029
- DUF3591; Protein of unknown function (DUF3591)
- pfam15288
Location:1262 → 1297
- zf-CCHC_6; Zinc knuckle
-
NM_004606.5 → NP_004597.3 transcription initiation factor TFIID subunit 1 isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) lacks an alternate in-frame exon in the 3' coding region, compared to variant 3, resulting in an isoform (1) that is 2 aa shorter than isoform 3. The exon combination of this variant is supported by mRNA annotation on DNA accession AY623109.1.
- Source sequence(s)
-
AB300418, AL590763
- Consensus CDS
-
CCDS14412.2
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
- Related
- ENSP00000406549.2, ENST00000423759.6
- Conserved Domains (5) summary
-
- cd05511
Location:1508 → 1620
- Bromo_TFIID; Bromodomain, TFIID-like subfamily. Human TAFII250 (or TAF250) is the largest subunit of TFIID, a large multi-domain complex, which initiates the assembly of the transcription machinery. TAFII250 contains two bromodomains that specifically bind to ...
- pfam09247
Location:8 → 66
- TBP-binding; TATA box-binding protein binding
- pfam12157
Location:566 → 1029
- DUF3591; Protein of unknown function (DUF3591)
- pfam15288
Location:1262 → 1297
- zf-CCHC_6; Zinc knuckle
- NF033845
Location:1636 → 1872
- MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
-
NM_138923.4 → NP_620278.2 transcription initiation factor TFIID subunit 1 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, and lacks an alternate in-frame exon in the 3' coding region, compared to variant 3. The encoded isoform (2) is shorter than isoform 3.
- Source sequence(s)
-
AL590763, D90359
- Consensus CDS
-
CCDS35325.2
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
- Related
- ENSP00000362895.5, ENST00000373790.9
- Conserved Domains (5) summary
-
- cd05511
Location:1487 → 1599
- Bromo_TFIID; Bromodomain, TFIID-like subfamily. Human TAFII250 (or TAF250) is the largest subunit of TFIID, a large multi-domain complex, which initiates the assembly of the transcription machinery. TAFII250 contains two bromodomains that specifically bind to ...
- NF033609
Location:1616 → 1851
- MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA
- pfam09247
Location:8 → 66
- TBP-binding; TATA box-binding protein binding
- pfam12157
Location:545 → 1008
- DUF3591; Protein of unknown function (DUF3591)
- pfam15288
Location:1241 → 1276
- zf-CCHC_6; Zinc knuckle
RNA
-
NR_104387.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (4, also known as 2a) includes a combination of TAF1 and DYT3 exons, and it thus contains alternate 3' exon structure, compared to variant 3. This variant is represented as non-coding because use of the expected translational start codon, as used in variant 3, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). The 5' exon structure of this transcript is inferred from transcript alignments, while the 3' exon structure is supported by accession AJ549248.3 and data in PMID: 12928496.
- Source sequence(s)
-
AB300418, AJ549248, AL590763
-
NR_104388.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (5, also known as 2b) includes a combination of TAF1 and DYT3 exons, and it thus contains alternate 3' exon structure, compared to variant 3. This variant is represented as non-coding because use of the expected translational start codon, as used in variant 3, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). The 5' exon structure of this transcript is inferred from transcript alignments, while the 3' exon structure is supported by accession AJ549249.2 and data in PMID: 12928496.
- Source sequence(s)
-
AB300418, AJ549249, AL590763
-
NR_104389.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (6, also known as 2c) includes a combination of TAF1 and DYT3 exons, and it thus contains alternate 3' exon structure, compared to variant 3. This variant is represented as non-coding because use of the expected translational start codon, as used in variant 3, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). The 5' exon structure of this transcript is inferred from transcript alignments, while the 3' exon structure is supported by accession AJ549250.3 and data in PMID: 12928496.
- Source sequence(s)
-
AB300418, AJ549250, AL590763
-
NR_104390.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (7, also known as 2d) includes a combination of TAF1 and DYT3 exons, and it thus contains alternate 3' exon structure, compared to variant 3. This variant is represented as non-coding because use of the expected translational start codon, as used in variant 3, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). The 5' exon structure of this transcript is inferred from transcript alignments, while the 3' exon structure is supported by accession AJ555148.2 and data in PMID: 12928496.
- Source sequence(s)
-
AB300418, AJ555148, AL590763
-
NR_104391.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (8, also known as 2e) includes a combination of TAF1 and DYT3 exons, and it thus contains alternate 3' exon structure, compared to variant 3. This variant is represented as non-coding because use of the expected translational start codon, as used in variant 3, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). The 5' exon structure of this transcript is inferred from transcript alignments, while the 3' exon structure is supported by accession AJ555149.2 and data in PMID: 12928496.
- Source sequence(s)
-
AB300418, AJ555149, AL590763
-
NR_104392.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (9, also known as 2f) includes a combination of TAF1 and DYT3 exons, and it thus contains alternate 3' exon structure, compared to variant 3. This variant is represented as non-coding because use of the expected translational start codon, as used in variant 3, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). The 5' exon structure of this transcript is inferred from transcript alignments, while the 3' exon structure is supported by accession AM711892.1 and data in PMID: 17952504.
- Source sequence(s)
-
AB300418, AJ549248, AL590763, AM711892
-
NR_104393.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (10, also known as 2g) includes a combination of TAF1 and DYT3 exons, and it thus contains alternate 3' exon structure, compared to variant 3. This variant is represented as non-coding because use of the expected translational start codon, as used in variant 3, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). The 5' exon structure of this transcript is inferred from transcript alignments, while the 3' exon structure is supported by accession AM711893.1 and data in PMID: 17952504.
- Source sequence(s)
-
AB300418, AJ549248, AL590763, AM711893
-
NR_104394.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (11, also known as 2h) includes a combination of TAF1 and DYT3 exons, and it thus contains alternate 3' exon structure, compared to variant 3. This variant is represented as non-coding because use of the expected translational start codon, as used in variant 3, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). The 5' exon structure of this transcript is inferred from transcript alignments, while the 3' exon structure is supported by accession AM711894.1 and data in PMID: 17952504.
- Source sequence(s)
-
AB300418, AJ549248, AL590763, AM711894
-
NR_104395.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (12, also known as 2i) includes a combination of TAF1 and DYT3 exons, and it thus contains alternate 3' exon structure, compared to variant 3. This variant is represented as non-coding because use of the expected translational start codon, as used in variant 3, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). The 5' exon structure of this transcript is inferred from transcript alignments, while the 3' exon structure is supported by accession AM711895.1 and data in PMID: 17952504.
- Source sequence(s)
-
AB300418, AJ549248, AL590763, AM711895
-
NR_104396.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (13, also known as 3) includes independently transcribed DYT3 exons only and it thus lacks similarity to variant 3, but it shares DYT3 exon structure with variants 4 through 12. This variant is represented as non-coding because it lacks the entire coding region found in variant 3. This variant is supported by accession AJ549246.2 and data in PMIDs: 12928496 and 23184149.
- Source sequence(s)
-
AJ549246
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000023.11 Reference GRCh38.p14 Primary Assembly
- Range
-
71366357..71530525
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047442397.1 → XP_047298353.1 transcription initiation factor TFIID subunit 1 isoform X7
- UniProtKB/TrEMBL
-
A0A804HK58
-
XM_047442401.1 → XP_047298357.1 transcription initiation factor TFIID subunit 1 isoform X11
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_047442398.1 → XP_047298354.1 transcription initiation factor TFIID subunit 1 isoform X8
- UniProtKB/TrEMBL
-
A0A804HK58
-
XM_047442402.1 → XP_047298358.1 transcription initiation factor TFIID subunit 1 isoform X12
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_047442403.1 → XP_047298359.1 transcription initiation factor TFIID subunit 1 isoform X13
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_047442391.1 → XP_047298347.1 transcription initiation factor TFIID subunit 1 isoform X1
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
- UniProtKB/TrEMBL
-
A0A804HIC2
- Related
- ENSP00000506996.1, ENST00000683782.1
-
XM_047442395.1 → XP_047298351.1 transcription initiation factor TFIID subunit 1 isoform X5
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_047442392.1 → XP_047298348.1 transcription initiation factor TFIID subunit 1 isoform X2
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_047442396.1 → XP_047298352.1 transcription initiation factor TFIID subunit 1 isoform X6
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_047442393.1 → XP_047298349.1 transcription initiation factor TFIID subunit 1 isoform X3
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_047442399.1 → XP_047298355.1 transcription initiation factor TFIID subunit 1 isoform X9
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
- Conserved Domains (5) summary
-
- cd05511
Location:1487 → 1599
- Bromo_TFIID; Bromodomain, TFIID-like subfamily. Human TAFII250 (or TAF250) is the largest subunit of TFIID, a large multi-domain complex, which initiates the assembly of the transcription machinery. TAFII250 contains two bromodomains that specifically bind to ...
- NF033609
Location:1616 → 1851
- MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA
- pfam09247
Location:8 → 66
- TBP-binding; TATA box-binding protein binding
- pfam12157
Location:545 → 1008
- DUF3591; Protein of unknown function (DUF3591)
- pfam15288
Location:1241 → 1276
- zf-CCHC_6; Zinc knuckle
-
XM_047442394.1 → XP_047298350.1 transcription initiation factor TFIID subunit 1 isoform X4
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_047442400.1 → XP_047298356.1 transcription initiation factor TFIID subunit 1 isoform X10
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_047442404.1 → XP_047298360.1 transcription initiation factor TFIID subunit 1 isoform X14
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
- Related
- ENSP00000507781.1, ENST00000683202.1
-
XM_024452430.2 → XP_024308198.2 transcription initiation factor TFIID subunit 1 isoform X16
- UniProtKB/TrEMBL
-
A0A804HK58
-
XM_047442406.1 → XP_047298362.1 transcription initiation factor TFIID subunit 1 isoform X17
-
XM_005262300.3 → XP_005262357.2 transcription initiation factor TFIID subunit 1 isoform X18
- UniProtKB/TrEMBL
-
A0A804HHS0
- Related
- ENSP00000506729.1, ENST00000683715.1
-
XM_047442405.1 → XP_047298361.1 transcription initiation factor TFIID subunit 1 isoform X15
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
Alternate T2T-CHM13v2.0
Genomic
-
NC_060947.1 Alternate T2T-CHM13v2.0
- Range
-
69800459..69963776
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054327634.1 → XP_054183609.1 transcription initiation factor TFIID subunit 1 isoform X7
- UniProtKB/TrEMBL
-
A0A804HK58
-
XM_054327638.1 → XP_054183613.1 transcription initiation factor TFIID subunit 1 isoform X11
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_054327635.1 → XP_054183610.1 transcription initiation factor TFIID subunit 1 isoform X8
- UniProtKB/TrEMBL
-
A0A804HK58
-
XM_054327639.1 → XP_054183614.1 transcription initiation factor TFIID subunit 1 isoform X12
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_054327640.1 → XP_054183615.1 transcription initiation factor TFIID subunit 1 isoform X13
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_054327628.1 → XP_054183603.1 transcription initiation factor TFIID subunit 1 isoform X1
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
- UniProtKB/TrEMBL
-
A0A804HIC2
-
XM_054327632.1 → XP_054183607.1 transcription initiation factor TFIID subunit 1 isoform X5
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_054327629.1 → XP_054183604.1 transcription initiation factor TFIID subunit 1 isoform X2
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_054327633.1 → XP_054183608.1 transcription initiation factor TFIID subunit 1 isoform X6
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_054327630.1 → XP_054183605.1 transcription initiation factor TFIID subunit 1 isoform X3
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_054327636.1 → XP_054183611.1 transcription initiation factor TFIID subunit 1 isoform X9
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_054327631.1 → XP_054183606.1 transcription initiation factor TFIID subunit 1 isoform X4
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_054327637.1 → XP_054183612.1 transcription initiation factor TFIID subunit 1 isoform X10
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_054327641.1 → XP_054183616.1 transcription initiation factor TFIID subunit 1 isoform X14
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03
-
XM_054327643.1 → XP_054183618.1 transcription initiation factor TFIID subunit 1 isoform X16
- UniProtKB/TrEMBL
-
A0A804HK58
-
XM_054327644.1 → XP_054183619.1 transcription initiation factor TFIID subunit 1 isoform X17
-
XM_054327645.1 → XP_054183620.1 transcription initiation factor TFIID subunit 1 isoform X18
- UniProtKB/TrEMBL
-
A0A804HHS0
-
XM_054327642.1 → XP_054183617.1 transcription initiation factor TFIID subunit 1 isoform X15
- UniProtKB/Swiss-Prot
- A5CVC8, A5CVC9, A5CVD0, A5CVD1, B1Q2X3, P21675, Q59FZ3, Q6IUZ1, Q70Q86, Q70Q87, Q70T00, Q70T01, Q70T02, Q70T03