U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Hnf4g hepatocyte nuclear factor 4, gamma [ Mus musculus (house mouse) ]

    Gene ID: 30942, updated on 18-Sep-2024

    Summary

    Official Symbol
    Hnf4gprovided by MGI
    Official Full Name
    hepatocyte nuclear factor 4, gammaprovided by MGI
    Primary source
    MGI:MGI:1353604
    See related
    Ensembl:ENSMUSG00000017688 AllianceGenome:MGI:1353604
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NR2A2
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and nuclear receptor activity. Acts upstream of or within positive regulation of transcription, DNA-templated. Predicted to be located in several cellular components, including intercellular bridge; mitotic spindle; and nucleoplasm. Predicted to be part of transcription regulator complex. Is expressed in several structures, including genitourinary system; gut; and nervous system. Orthologous to human HNF4G (hepatocyte nuclear factor 4 gamma). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in large intestine adult (RPKM 18.4), small intestine adult (RPKM 7.7) and 3 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Hnf4g in Genome Data Viewer
    Location:
    3 A1; 3 1.82 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (3573090..3724863)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (3508030..3659800)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene nuclear encoded tRNA lysine 31 (anticodon CTT) Neighboring gene STARR-seq mESC enhancer starr_06769 Neighboring gene RAB3 GTPase activating protein subunit 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_06770 Neighboring gene STARR-seq mESC enhancer starr_06771 Neighboring gene STARR-seq mESC enhancer starr_06773 Neighboring gene STARR-seq mESC enhancer starr_06774 Neighboring gene STARR-seq mESC enhancer starr_06775 Neighboring gene STARR-seq mESC enhancer starr_06776 Neighboring gene STARR-seq mESC enhancer starr_06777 Neighboring gene STARR-seq mESC enhancer starr_06779 Neighboring gene STARR-seq mESC enhancer starr_06780 Neighboring gene ribosomal protein S24, pseudogene 2 Neighboring gene POU domain, class 5, transcription factor 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in intercellular bridge ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitotic spindle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of transcription regulator complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    General protein information

    Preferred Names
    hepatocyte nuclear factor 4-gamma
    Names
    HNF-4-gamma
    nuclear receptor subfamily 2 group A member 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001395870.1NP_001382799.1  hepatocyte nuclear factor 4-gamma isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC157926, AC170259
      UniProtKB/TrEMBL
      E9QPS1, Q059V1
      Related
      ENSMUSP00000104031.2, ENSMUST00000108394.4
      Conserved Domains (2) summary
      cd06931
      Location:157378
      NR_LBD_HNF4_like; The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes
      cd06960
      Location:66141
      NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
    2. NM_013920.3NP_038948.2  hepatocyte nuclear factor 4-gamma isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC157764, AC157926, AC170259
      Consensus CDS
      CCDS17226.1
      UniProtKB/Swiss-Prot
      Q9WUU6
      UniProtKB/TrEMBL
      Q059V1
      Related
      ENSMUSP00000104030.3, ENSMUST00000108393.9
      Conserved Domains (2) summary
      cd06931
      Location:103324
      NR_LBD_HNF4_like; The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes
      cd06960
      Location:1287
      NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      3573090..3724863
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)