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    pou5f3 POU domain, class 5, transcription factor 3 [ Danio rerio (zebrafish) ]

    Gene ID: 30333, updated on 9-Apr-2018
    Official Symbol
    pou5f3provided by ZNC
    Official Full Name
    POU domain, class 5, transcription factor 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-980526-485
    See related
    Ensembl:ENSDARG00000044774 Vega:OTTDARG00000032106
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    gp9; spg; gp-9; oct4; pou2; POU-2; cb197; pou5f1; spg/pou2; chunp6868; wu:fd18d06; etID49452.21
    Location:
    chromosome: 21
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (13685853..13691117, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (13589128..13594388, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene chloride intracellular channel 3 Neighboring gene fucosyltransferase 7 (alpha (1,3) fucosyltransferase) Neighboring gene neural proliferation, differentiation and control, 1a Neighboring gene si:ch211-282j22.3

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    DNA binding transcription factor activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein heterodimerization activity IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    sequence-specific DNA binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    anatomical structure morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    brain development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    brain segmentation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    dorsal/ventral pattern formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ectoderm development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    embryonic pattern specification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    endoderm formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    epiboly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    epiboly involved in gastrulation with mouth forming second IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    fin regeneration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    hindbrain development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mesoderm development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    midbrain-hindbrain boundary development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    morphogenesis of embryonic epithelium IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of transcription, DNA-templated IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of DNA methylation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of endodermal cell fate specification IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    POU domain, class 5, transcription factor 1
    Names
    POU domain gene 2
    POU domain protein 2
    spiel-ohne-grenzen
    spiel-ohne-grenzen/pou2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131112.1NP_571187.1  POU domain, class 5, transcription factor 1

      See identical proteins and their annotated locations for NP_571187.1

      Status: PROVISIONAL

      Source sequence(s)
      X84224
      UniProtKB/Swiss-Prot
      Q90270
      UniProtKB/TrEMBL
      A0A0R4I9C7
      Related
      ENSDARP00000065816.3, OTTDARP00000035418, ENSDART00000065817.4, OTTDART00000044767
      Conserved Domains (2) summary
      smart00352
      Location:259323
      POU; Found in Pit-Oct-Unc transcription factors
      pfam00046
      Location:346399
      Homeobox; Homeobox domain

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      13685853..13691117 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005161103.4XP_005161160.1  POU domain, class 5, transcription factor 1 isoform X1

      Conserved Domains (2) summary
      smart00352
      Location:248322
      POU; Found in Pit-Oct-Unc transcription factors
      pfam00046
      Location:345398
      Homeobox; Homeobox domain
    2. XM_005161104.4XP_005161161.1  POU domain, class 5, transcription factor 1 isoform X2

      Conserved Domains (2) summary
      smart00352
      Location:259323
      POU; Found in Pit-Oct-Unc transcription factors
      smart00389
      Location:343382
      HOX; Homeodomain
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