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    Trim2 tripartite motif-containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 80890, updated on 5-Aug-2018

    Summary

    Official Symbol
    Trim2provided by MGI
    Official Full Name
    tripartite motif-containing 2provided by MGI
    Primary source
    MGI:MGI:1933163
    See related
    Ensembl:ENSMUSG00000027993 Vega:OTTMUSG00000017469
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    narf; mKIAA0517
    Expression
    Broad expression in CNS E18 (RPKM 15.0), cerebellum adult (RPKM 13.7) and 23 other tissues See more
    Orthologs

    Genomic context

    See Trim2 in Genome Data Viewer
    Location:
    3; 3 F1
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (84160439..84305841, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (83965796..84024799, complement)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 30458 Neighboring gene meiotic nuclear divisions 1 Neighboring gene ribosomal protein L36a pseudogene Neighboring gene nuclear encoded tRNA glycine 9 (anticodon GCC) Neighboring gene predicted gene, 40078 Neighboring gene RIKEN cDNA 4930565D16 gene Neighboring gene FH2 domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA0517

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    myosin binding NAS
    Non-traceable Author Statement
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ubiquitin protein ligase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ubiquitin-protein transferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    zinc ion binding NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    cellular response to leukemia inhibitory factor IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of neuron apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of neuron apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm NAS
    Non-traceable Author Statement
    more info
    PubMed 
    intracellular IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    tripartite motif-containing protein 2
    Names
    E3 ubiquitin-protein ligase TRIM2
    RING-type E3 ubiquitin transferase TRIM2
    neural activity-related ring finger protein
    tripartite motif protein 2
    tripartite motif protein TRIM2
    NP_001258654.1
    NP_001258655.1
    NP_001258656.1
    NP_001258657.1
    NP_109631.2
    XP_011238598.1
    XP_011238599.1
    XP_011238600.1
    XP_011238601.1
    XP_011238602.1
    XP_011238603.1
    XP_011238604.1
    XP_011238605.1
    XP_011238606.1
    XP_011238607.1
    XP_017175302.1
    XP_017175303.1
    XP_017175304.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001271725.1NP_001258654.1  tripartite motif-containing protein 2 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AK147275, CA751006, CJ100776
      Consensus CDS
      CCDS71257.1
      UniProtKB/Swiss-Prot
      Q9ESN6
      UniProtKB/TrEMBL
      E9QKC6
      Related
      ENSMUSP00000049902.4, OTTMUSP00000019078, ENSMUST00000054990.10, OTTMUST00000042446
      Conserved Domains (7) summary
      smart00502
      Location:187313
      BBC; B-Box C-terminal domain
      smart00336
      Location:139180
      BBOX; B-Box-type zinc finger
      smart00557
      Location:351447
      IG_FLMN; Filamin-type immunoglobulin domains
      COG3391
      Location:516761
      YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
      cd00162
      Location:4992
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd14960
      Location:497770
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      pfam00630
      Location:351444
      Filamin; Filamin/ABP280 repeat
    2. NM_001271726.1NP_001258655.1  tripartite motif-containing protein 2 isoform 2

      See identical proteins and their annotated locations for NP_001258655.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (2) has a shorter N-terminus, compared to isoform 1. Variants 2, 3, and 5 encode the same isoform (2).
      Source sequence(s)
      AC102235, AK147275, CA751006, CD802800
      Consensus CDS
      CCDS71256.1
      UniProtKB/Swiss-Prot
      Q9ESN6
      Related
      ENSMUSP00000103320.1, OTTMUSP00000019066, ENSMUST00000107692.7, OTTMUST00000042421
      Conserved Domains (5) summary
      smart00502
      Location:161287
      BBC; B-Box C-terminal domain
      smart00336
      Location:113154
      BBOX; B-Box-type zinc finger
      smart00557
      Location:325421
      IG_FLMN; Filamin-type immunoglobulin domains
      cd14960
      Location:471744
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      cd16767
      Location:2065
      RING-HC_TRIM2; RING finger, HC subclass, found in tripartite motif-containing protein 2 (TRIM2)
    3. NM_001271727.1NP_001258656.1  tripartite motif-containing protein 2 isoform 2

      See identical proteins and their annotated locations for NP_001258656.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (2) has a shorter N-terminus, compared to isoform 1. Variants 2, 3, and 5 encode the same isoform (2).
      Source sequence(s)
      AK147275, CA751006, CJ105472
      Consensus CDS
      CCDS71256.1
      UniProtKB/Swiss-Prot
      Q9ESN6
      Related
      ENSMUSP00000103319.1, OTTMUSP00000019079, ENSMUST00000107691.7, OTTMUST00000042447
      Conserved Domains (5) summary
      smart00502
      Location:161287
      BBC; B-Box C-terminal domain
      smart00336
      Location:113154
      BBOX; B-Box-type zinc finger
      smart00557
      Location:325421
      IG_FLMN; Filamin-type immunoglobulin domains
      cd14960
      Location:471744
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      cd16767
      Location:2065
      RING-HC_TRIM2; RING finger, HC subclass, found in tripartite motif-containing protein 2 (TRIM2)
    4. NM_001271728.1NP_001258657.1  tripartite motif-containing protein 2 isoform 2

      See identical proteins and their annotated locations for NP_001258657.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (2) has a shorter N-terminus, compared to isoform 1. Variants 2, 3, and 5 encode the same isoform (2).
      Source sequence(s)
      AK147275, BC058961, CA751006
      Consensus CDS
      CCDS71256.1
      UniProtKB/Swiss-Prot
      Q9ESN6
      Related
      ENSMUSP00000069922.6, OTTMUSP00000019081, ENSMUST00000065380.12, OTTMUST00000042449
      Conserved Domains (5) summary
      smart00502
      Location:161287
      BBC; B-Box C-terminal domain
      smart00336
      Location:113154
      BBOX; B-Box-type zinc finger
      smart00557
      Location:325421
      IG_FLMN; Filamin-type immunoglobulin domains
      cd14960
      Location:471744
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      cd16767
      Location:2065
      RING-HC_TRIM2; RING finger, HC subclass, found in tripartite motif-containing protein 2 (TRIM2)
    5. NM_030706.3NP_109631.2  tripartite motif-containing protein 2 isoform 3

      See identical proteins and their annotated locations for NP_109631.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) contains a distinct 5' UTR and differs in the 5' coding region, compared to variant 1. The resulting isoform (3) has a shorter and distinct N-terminus, compared to isoform 1.
      Source sequence(s)
      AK147275, CA751006, CD803806
      Consensus CDS
      CCDS17437.2
      UniProtKB/Swiss-Prot
      Q9ESN6
      UniProtKB/TrEMBL
      Q3UHH4
      Related
      ENSMUSP00000103323.2, OTTMUSP00000019080, ENSMUST00000107695.8, OTTMUST00000042448
      Conserved Domains (7) summary
      smart00502
      Location:178304
      BBC; B-Box C-terminal domain
      smart00336
      Location:130171
      BBOX; B-Box-type zinc finger
      smart00557
      Location:342438
      IG_FLMN; Filamin-type immunoglobulin domains
      COG3391
      Location:507752
      YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
      cd00162
      Location:4083
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd14960
      Location:488761
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      pfam00630
      Location:342435
      Filamin; Filamin/ABP280 repeat

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      84160439..84305841 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011240301.2XP_011238603.1  tripartite motif-containing protein 2 isoform X6

      See identical proteins and their annotated locations for XP_011238603.1

      Conserved Domains (8) summary
      smart00502
      Location:161287
      BBC; B-Box C-terminal domain
      smart00336
      Location:113154
      BBOX; B-Box-type zinc finger
      smart00557
      Location:325421
      IG_FLMN; Filamin-type immunoglobulin domains
      COG3391
      Location:490739
      YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
      cd00162
      Location:2366
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd14960
      Location:471748
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      pfam00630
      Location:325418
      Filamin; Filamin/ABP280 repeat
      sd00039
      Location:492527
      7WD40; WD40 repeat [structural motif]
    2. XM_011240298.2XP_011238600.1  tripartite motif-containing protein 2 isoform X4

      Conserved Domains (8) summary
      smart00502
      Location:179305
      BBC; B-Box C-terminal domain
      smart00336
      Location:131172
      BBOX; B-Box-type zinc finger
      smart00557
      Location:343439
      IG_FLMN; Filamin-type immunoglobulin domains
      COG3391
      Location:508757
      YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
      cd00162
      Location:4184
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd14960
      Location:489766
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      pfam00630
      Location:343436
      Filamin; Filamin/ABP280 repeat
      sd00039
      Location:510545
      7WD40; WD40 repeat [structural motif]
    3. XM_017319814.1XP_017175303.1  tripartite motif-containing protein 2 isoform X7

      UniProtKB/Swiss-Prot
      Q9ESN6
      Conserved Domains (5) summary
      smart00502
      Location:161287
      BBC; B-Box C-terminal domain
      smart00336
      Location:113154
      BBOX; B-Box-type zinc finger
      smart00557
      Location:325421
      IG_FLMN; Filamin-type immunoglobulin domains
      cd14960
      Location:471744
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      cd16767
      Location:2065
      RING-HC_TRIM2; RING finger, HC subclass, found in tripartite motif-containing protein 2 (TRIM2)
    4. XM_017319813.1XP_017175302.1  tripartite motif-containing protein 2 isoform X3

    5. XM_011240302.1XP_011238604.1  tripartite motif-containing protein 2 isoform X6

      See identical proteins and their annotated locations for XP_011238604.1

      Conserved Domains (8) summary
      smart00502
      Location:161287
      BBC; B-Box C-terminal domain
      smart00336
      Location:113154
      BBOX; B-Box-type zinc finger
      smart00557
      Location:325421
      IG_FLMN; Filamin-type immunoglobulin domains
      COG3391
      Location:490739
      YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
      cd00162
      Location:2366
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd14960
      Location:471748
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      pfam00630
      Location:325418
      Filamin; Filamin/ABP280 repeat
      sd00039
      Location:492527
      7WD40; WD40 repeat [structural motif]
    6. XM_011240297.2XP_011238599.1  tripartite motif-containing protein 2 isoform X2

      Conserved Domains (8) summary
      smart00502
      Location:183309
      BBC; B-Box C-terminal domain
      smart00336
      Location:135176
      BBOX; B-Box-type zinc finger
      smart00557
      Location:347443
      IG_FLMN; Filamin-type immunoglobulin domains
      COG3391
      Location:512761
      YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
      cd00162
      Location:4588
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd14960
      Location:493770
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      pfam00630
      Location:347440
      Filamin; Filamin/ABP280 repeat
      sd00039
      Location:514549
      7WD40; WD40 repeat [structural motif]
    7. XM_011240296.1XP_011238598.1  tripartite motif-containing protein 2 isoform X1

      Conserved Domains (8) summary
      smart00502
      Location:187313
      BBC; B-Box C-terminal domain
      smart00336
      Location:139180
      BBOX; B-Box-type zinc finger
      smart00557
      Location:351447
      IG_FLMN; Filamin-type immunoglobulin domains
      COG3391
      Location:516765
      YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
      cd00162
      Location:4992
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd14960
      Location:497774
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      pfam00630
      Location:351444
      Filamin; Filamin/ABP280 repeat
      sd00039
      Location:518553
      7WD40; WD40 repeat [structural motif]
    8. XM_011240300.2XP_011238602.1  tripartite motif-containing protein 2 isoform X6

      See identical proteins and their annotated locations for XP_011238602.1

      Conserved Domains (8) summary
      smart00502
      Location:161287
      BBC; B-Box C-terminal domain
      smart00336
      Location:113154
      BBOX; B-Box-type zinc finger
      smart00557
      Location:325421
      IG_FLMN; Filamin-type immunoglobulin domains
      COG3391
      Location:490739
      YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
      cd00162
      Location:2366
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd14960
      Location:471748
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      pfam00630
      Location:325418
      Filamin; Filamin/ABP280 repeat
      sd00039
      Location:492527
      7WD40; WD40 repeat [structural motif]
    9. XM_011240299.2XP_011238601.1  tripartite motif-containing protein 2 isoform X5

      Conserved Domains (8) summary
      smart00502
      Location:178304
      BBC; B-Box C-terminal domain
      smart00336
      Location:130171
      BBOX; B-Box-type zinc finger
      smart00557
      Location:342438
      IG_FLMN; Filamin-type immunoglobulin domains
      COG3391
      Location:507756
      YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
      cd00162
      Location:4083
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd14960
      Location:488765
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      pfam00630
      Location:342435
      Filamin; Filamin/ABP280 repeat
      sd00039
      Location:509544
      7WD40; WD40 repeat [structural motif]
    10. XM_017319815.1XP_017175304.1  tripartite motif-containing protein 2 isoform X8

    11. XM_011240304.2XP_011238606.1  tripartite motif-containing protein 2 isoform X6

      See identical proteins and their annotated locations for XP_011238606.1

      Conserved Domains (8) summary
      smart00502
      Location:161287
      BBC; B-Box C-terminal domain
      smart00336
      Location:113154
      BBOX; B-Box-type zinc finger
      smart00557
      Location:325421
      IG_FLMN; Filamin-type immunoglobulin domains
      COG3391
      Location:490739
      YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
      cd00162
      Location:2366
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd14960
      Location:471748
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      pfam00630
      Location:325418
      Filamin; Filamin/ABP280 repeat
      sd00039
      Location:492527
      7WD40; WD40 repeat [structural motif]
    12. XM_011240303.2XP_011238605.1  tripartite motif-containing protein 2 isoform X6

      See identical proteins and their annotated locations for XP_011238605.1

      Conserved Domains (8) summary
      smart00502
      Location:161287
      BBC; B-Box C-terminal domain
      smart00336
      Location:113154
      BBOX; B-Box-type zinc finger
      smart00557
      Location:325421
      IG_FLMN; Filamin-type immunoglobulin domains
      COG3391
      Location:490739
      YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
      cd00162
      Location:2366
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd14960
      Location:471748
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      pfam00630
      Location:325418
      Filamin; Filamin/ABP280 repeat
      sd00039
      Location:492527
      7WD40; WD40 repeat [structural motif]
    13. XM_011240305.1XP_011238607.1  tripartite motif-containing protein 2 isoform X9

      Conserved Domains (3) summary
      smart00336
      Location:113154
      BBOX; B-Box-type zinc finger
      cd00162
      Location:2366
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cl23765
      Location:161235
      iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
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