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    Nudt17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 [ Mus musculus (house mouse) ]

    Gene ID: 78373, updated on 9-Sep-2018

    Summary

    Official Symbol
    Nudt17provided by MGI
    Official Full Name
    nudix (nucleoside diphosphate linked moiety X)-type motif 17provided by MGI
    Primary source
    MGI:MGI:1925623
    See related
    Ensembl:ENSMUSG00000028100 Vega:OTTMUSG00000053149
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2410015C20Rik
    Expression
    Ubiquitous expression in mammary gland adult (RPKM 3.2), thymus adult (RPKM 2.5) and 26 other tissues See more
    Orthologs

    Genomic context

    See Nudt17 in Genome Data Viewer
    Location:
    3; 3 F2.1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (96705892..96708934, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (96509815..96512483, complement)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene ribosomal protein L21, pseudogene 11 Neighboring gene ankyrin repeat domain 35 Neighboring gene protein inhibitor of activated STAT 3 Neighboring gene polymerase (RNA) III (DNA directed) polypeptide C Neighboring gene ring finger protein 115

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    NADH pyrophosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    NAD catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    NADH metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    NADP catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    nucleoside diphosphate-linked moiety X motif 17
    Names
    nudix motif 17
    NP_001156397.1
    NP_084370.1
    XP_006502379.1
    XP_006502380.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001162925.1NP_001156397.1  nucleoside diphosphate-linked moiety X motif 17 isoform 2

      See identical proteins and their annotated locations for NP_001156397.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate in-frame coding exon compared to variant 1, resulting in a longer isoform (2) with a different internal protein segment compared to isoform 1.
      Source sequence(s)
      AC112261, AK019109, AK134929
      Consensus CDS
      CCDS51009.1
      UniProtKB/Swiss-Prot
      Q9CWD3
      Related
      ENSMUSP00000029742.5, OTTMUSP00000070765, ENSMUST00000029742.8, OTTMUST00000132853
      Conserved Domains (1) summary
      cl00447
      Location:92251
      Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...
    2. NM_030094.1NP_084370.1  nucleoside diphosphate-linked moiety X motif 17 isoform 1

      See identical proteins and their annotated locations for NP_084370.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the predominant transcript and encodes isoform 1.
      Source sequence(s)
      AK019109, AK134929
      Consensus CDS
      CCDS51008.1
      UniProtKB/Swiss-Prot
      Q9CWD3
      Related
      ENSMUSP00000129851.1, OTTMUSP00000070764, ENSMUST00000171249.5, OTTMUST00000132852
      Conserved Domains (1) summary
      cl00447
      Location:92234
      Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      96705892..96708934 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006502316.3XP_006502379.1  nucleoside diphosphate-linked moiety X motif 17 isoform X1

      Conserved Domains (1) summary
      cl00447
      Location:79238
      Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...
    2. XM_006502317.3XP_006502380.1  nucleoside diphosphate-linked moiety X motif 17 isoform X2

      Conserved Domains (1) summary
      cl00447
      Location:79221
      Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...

    RNA

    1. XR_375600.3 RNA Sequence

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