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    Tmprss12 transmembrane (C-terminal) protease, serine 12 [ Mus musculus (house mouse) ]

    Gene ID: 75002, updated on 31-Jan-2019

    Summary

    Official Symbol
    Tmprss12provided by MGI
    Official Full Name
    transmembrane (C-terminal) protease, serine 12provided by MGI
    Primary source
    MGI:MGI:1922252
    See related
    Ensembl:ENSMUSG00000045631
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4930478A21Rik
    Expression
    Restricted expression toward testis adult (RPKM 14.1) See more
    Orthologs

    Genomic context

    See Tmprss12 in Genome Data Viewer
    Location:
    15; 15 F1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 15 NC_000081.6 (100280837..100293053)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (100111268..100123484)

    Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene disco interacting protein 2 homolog B Neighboring gene activating transcription factor 1 Neighboring gene predicted gene, 33666 Neighboring gene methyltransferase like 7A1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    serine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    transmembrane protease serine 12

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_183109.3NP_898932.2  transmembrane protease serine 12 precursor

      See identical proteins and their annotated locations for NP_898932.2

      Status: PROVISIONAL

      Source sequence(s)
      AK132967
      Consensus CDS
      CCDS49732.1
      UniProtKB/Swiss-Prot
      Q3V0Q7
      Related
      ENSMUSP00000093914.4, ENSMUST00000096200.5
      Conserved Domains (2) summary
      smart00020
      Location:65300
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:66300
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000081.6 Reference GRCm38.p4 C57BL/6J

      Range
      100280837..100293053
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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