Format

Send to:

Choose Destination
    • Showing Current items.

    Casz1 castor zinc finger 1 [ Mus musculus (house mouse) ]

    Gene ID: 69743, updated on 18-Sep-2018

    Summary

    Official Symbol
    Casz1provided by MGI
    Official Full Name
    castor zinc finger 1provided by MGI
    Primary source
    MGI:MGI:1196251
    See related
    Ensembl:ENSMUSG00000028977 Vega:OTTMUSG00000010931
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cst; AV096627; BC040081; D4Ertd432e; 2410019P08Rik
    Expression
    Broad expression in small intestine adult (RPKM 25.0), duodenum adult (RPKM 22.7) and 16 other tissues See more
    Orthologs

    Genomic context

    See Casz1 in Genome Data Viewer
    Location:
    4 E2; 4 78.87 cM
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (148804367..148954893)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (148178501..148329001)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 32897 Neighboring gene predicted gene, 42350 Neighboring gene predicted gene, 42352 Neighboring gene predicted gene 13205 Neighboring gene predicted gene 17029 Neighboring gene predicted gene 17029 Neighboring gene peroxisomal biogenesis factor 14 Neighboring gene predicted gene, 42351

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC31683

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of amacrine cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of neuron differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of retinal cone cell fate commitment IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    retinal bipolar neuron differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    retinal rod cell fate commitment IDA
    Inferred from Direct Assay
    more info
    PubMed 
    retinal rod cell fate commitment IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    zinc finger protein castor homolog 1
    Names
    castor homolog 1, zinc finger
    castor-related protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001159344.1NP_001152816.1  zinc finger protein castor homolog 1 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AL607145, AL611967
      Consensus CDS
      CCDS51379.1
      UniProtKB/TrEMBL
      B1AS46
      Related
      ENSMUSP00000112978.1, OTTMUSP00000011748, ENSMUST00000122222.7, OTTMUST00000025638
      Conserved Domains (1) summary
      PHA03247
      Location:7991158
      PHA03247; large tegument protein UL36; Provisional
    2. NM_027195.2NP_081471.2  zinc finger protein castor homolog 1 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded protein (isoform 2) is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      BC075673, BI738136
      Consensus CDS
      CCDS38973.1
      UniProtKB/Swiss-Prot
      Q9CWL2
      Related
      ENSMUSP00000092035.3, OTTMUSP00000011746, ENSMUST00000094464.9, OTTMUST00000025635
      Conserved Domains (1) summary
      PHA03247
      Location:7991158
      PHA03247; large tegument protein UL36; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      148804367..148954893
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006539158.1XP_006539221.1  zinc finger protein castor homolog 1 isoform X2

      See identical proteins and their annotated locations for XP_006539221.1

      Conserved Domains (1) summary
      PHA03247
      Location:7991158
      PHA03247; large tegument protein UL36; Provisional
    2. XM_006539159.3XP_006539222.1  zinc finger protein castor homolog 1 isoform X2

      See identical proteins and their annotated locations for XP_006539222.1

      Conserved Domains (1) summary
      PHA03247
      Location:7991158
      PHA03247; large tegument protein UL36; Provisional
    3. XM_006539157.3XP_006539220.1  zinc finger protein castor homolog 1 isoform X1

      Conserved Domains (1) summary
      PHA03247
      Location:8231182
      PHA03247; large tegument protein UL36; Provisional
    4. XM_006539160.3XP_006539223.1  zinc finger protein castor homolog 1 isoform X3

      Conserved Domains (1) summary
      PHA03247
      Location:8231182
      PHA03247; large tegument protein UL36; Provisional

    Reference GRCm38.p4 NOD/MrkTac

    Genomic

    1. NT_166299.2 Reference GRCm38.p4 NOD/MrkTac

      Range
      2219753..2369399
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center