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    Rgmb repulsive guidance molecule family member B [ Mus musculus (house mouse) ]

    Gene ID: 68799, updated on 9-Sep-2018

    Summary

    Official Symbol
    Rgmbprovided by MGI
    Official Full Name
    repulsive guidance molecule family member Bprovided by MGI
    Primary source
    MGI:MGI:1916049
    See related
    Ensembl:ENSMUSG00000048027
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DRAGON; 1110059F19Rik
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 29.6), colon adult (RPKM 24.5) and 23 other tissues See more
    Orthologs

    Genomic context

    See Rgmb in Genome Data Viewer
    Location:
    17; 17 A2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (15804661..15831817, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (15943217..15963550, complement)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 5830433I10 gene Neighboring gene chromodomain helicase DNA binding protein 1 Neighboring gene predicted gene 3292 Neighboring gene eukaryotic translation initiation factor 3, subunit 6, pseudogene 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    coreceptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    identical protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    BMP signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    BMP signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell adhesion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    signal transduction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    anchored component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    anchored component of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endoplasmic reticulum-Golgi intermediate compartment IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    RGM domain family member B
    Names
    DRG11-responsive axonal guidance and outgrowth of neurite
    RGM domain family, member B
    repulsive guidance molecule B

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178615.3NP_848730.2  RGM domain family member B precursor

      See identical proteins and their annotated locations for NP_848730.2

      Status: PROVISIONAL

      Source sequence(s)
      AJ557514
      Consensus CDS
      CCDS37455.1
      UniProtKB/Swiss-Prot
      Q7TQ33
      Related
      ENSMUSP00000126177.1, ENSMUST00000170578.2
      Conserved Domains (2) summary
      pfam06534
      Location:229408
      RGM_C; Repulsive guidance molecule (RGM) C-terminus
      pfam06535
      Location:57224
      RGM_N; Repulsive guidance molecule (RGM) N-terminus

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      15804661..15831817 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006524865.2XP_006524928.1  RGM domain family member B isoform X2

      See identical proteins and their annotated locations for XP_006524928.1

      UniProtKB/Swiss-Prot
      Q7TQ33
      Conserved Domains (2) summary
      pfam06534
      Location:229408
      RGM_C; Repulsive guidance molecule (RGM) C-terminus
      pfam06535
      Location:57224
      RGM_N; Repulsive guidance molecule (RGM) N-terminus
    2. XM_006524864.3XP_006524927.1  RGM domain family member B isoform X1

      See identical proteins and their annotated locations for XP_006524927.1

      Conserved Domains (2) summary
      pfam06534
      Location:270449
      RGM_C; Repulsive guidance molecule (RGM) C-terminus
      pfam06535
      Location:98265
      RGM_N; Repulsive guidance molecule (RGM) N-terminus
    3. XM_006524863.2XP_006524926.1  RGM domain family member B isoform X1

      See identical proteins and their annotated locations for XP_006524926.1

      Conserved Domains (2) summary
      pfam06534
      Location:270449
      RGM_C; Repulsive guidance molecule (RGM) C-terminus
      pfam06535
      Location:98265
      RGM_N; Repulsive guidance molecule (RGM) N-terminus
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