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    Cwc27 CWC27 spliceosome-associated protein [ Mus musculus (house mouse) ]

    Gene ID: 67285, updated on 9-Sep-2018

    Summary

    Official Symbol
    Cwc27provided by MGI
    Official Full Name
    CWC27 spliceosome-associated proteinprovided by MGI
    Primary source
    MGI:MGI:1914535
    See related
    Ensembl:ENSMUSG00000021715 Vega:OTTMUSG00000029392
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NY-CO-10; Sdccag10; 3110009E13Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 1.3), CNS E14 (RPKM 0.7) and 21 other tissues See more
    Orthologs

    Genomic context

    See Cwc27 in Genome Data Viewer
    Location:
    13; 13 D1
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (104631322..104816969, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (105421407..105607033, complement)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase domain and WD repeat containing 1 Neighboring gene centromere protein K Neighboring gene a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6 Neighboring gene predicted gene 8680 Neighboring gene splicing regulatory glutamine/lysine-rich protein 1interacting protein 1 Neighboring gene shisa like 2B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    peptidyl-prolyl cis-trans isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    protein folding IEA
    Inferred from Electronic Annotation
    more info
     
    protein peptidyl-prolyl isomerization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    catalytic step 1 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    spliceosome-associated protein CWC27 homolog; peptidyl-prolyl cis-trans isomerase CWC27 homolog
    Names
    CWC27 spliceosome-associated protein homolog
    PPIase CWC27
    PPIase SDCCAG10
    peptidyl-prolyl cis-trans isomerase SDCCAG10
    probable inactive peptidyl-prolyl cis-trans isomerase CWC27 homolog
    serologically defined colon cancer antigen 10
    NP_080348.1
    XP_011242992.1
    XP_011242993.1
    XP_017171062.1
    XP_017171063.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360094.1NP_001347023.1  spliceosome-associated protein CWC27 homolog isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC132905, AC137691
      Conserved Domains (1) summary
      cd01925
      Location:8178
      cyclophilin_CeCYP16-like; cyclophilin_CeCYP16-like: cyclophilin-type peptidylprolyl cis- trans isomerase) (PPIase) domain similar to Caenorhabditis elegans cyclophilin 16. C. elegans CeCYP-16, compared to the archetypal cyclophilin Human cyclophilin A has, a reduced ...
    2. NM_026072.1NP_080348.1  spliceosome-associated protein CWC27 homolog isoform 1

      See identical proteins and their annotated locations for NP_080348.1

      Status: VALIDATED

      Source sequence(s)
      AK166770
      Consensus CDS
      CCDS26752.1
      UniProtKB/Swiss-Prot
      Q3TKY6
      Related
      ENSMUSP00000022228.6, OTTMUSP00000037595, ENSMUST00000022228.12, OTTMUST00000072847
      Conserved Domains (1) summary
      cd01925
      Location:8178
      cyclophilin_CeCYP16-like; cyclophilin_CeCYP16-like: cyclophilin-type peptidylprolyl cis- trans isomerase) (PPIase) domain similar to Caenorhabditis elegans cyclophilin 16. C. elegans CeCYP-16, compared to the archetypal cyclophilin Human cyclophilin A has, a reduced ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      104631322..104816969 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011244690.2XP_011242992.1  peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform X1

      Conserved Domains (1) summary
      cd01925
      Location:8178
      cyclophilin_CeCYP16-like; cyclophilin_CeCYP16-like: cyclophilin-type peptidylprolyl cis- trans isomerase) (PPIase) domain similar to Caenorhabditis elegans cyclophilin 16. C. elegans CeCYP-16, compared to the archetypal cyclophilin Human cyclophilin A has, a reduced ...
    2. XM_011244691.2XP_011242993.1  peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform X2

      Conserved Domains (1) summary
      cd01925
      Location:8178
      cyclophilin_CeCYP16-like; cyclophilin_CeCYP16-like: cyclophilin-type peptidylprolyl cis- trans isomerase) (PPIase) domain similar to Caenorhabditis elegans cyclophilin 16. C. elegans CeCYP-16, compared to the archetypal cyclophilin Human cyclophilin A has, a reduced ...
    3. XM_017315573.1XP_017171062.1  peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform X3

    4. XM_017315574.1XP_017171063.1  peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform X4

    RNA

    1. XR_001780798.1 RNA Sequence

    2. XR_001780799.1 RNA Sequence

    3. XR_001780800.1 RNA Sequence

    4. XR_001780801.1 RNA Sequence

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