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    Aggf1 angiogenic factor with G patch and FHA domains 1 [ Mus musculus (house mouse) ]

    Gene ID: 66549, updated on 12-Aug-2018

    Summary

    Official Symbol
    Aggf1provided by MGI
    Official Full Name
    angiogenic factor with G patch and FHA domains 1provided by MGI
    Primary source
    MGI:MGI:1913799
    See related
    Ensembl:ENSMUSG00000021681 Vega:OTTMUSG00000030737
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Peg3; VG5Q; AW112072; 2010009L17Rik; 2310029P06Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 16.3), CNS E11.5 (RPKM 15.1) and 28 other tissues See more
    Orthologs

    Genomic context

    See Aggf1 in Genome Data Viewer
    Location:
    13; 13 D1
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (95350683..95375357, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (96120671..96145289, complement)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 8B Neighboring gene predicted gene, 41025 Neighboring gene small nucleolar RNA, H/ACA box 47 Neighboring gene zinc finger, BED type containing 3 Neighboring gene corticotropin releasing hormone binding protein Neighboring gene S100 calcium binding protein, zeta

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    angiogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of angiogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of angiogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of endothelial cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular region ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    angiogenic factor with G patch and FHA domains 1
    Names
    angiogenic factor VG5Q

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025630.3NP_079906.2  angiogenic factor with G patch and FHA domains 1

      See identical proteins and their annotated locations for NP_079906.2

      Status: VALIDATED

      Source sequence(s)
      AA138180, AK132575, BC052410
      Consensus CDS
      CCDS26697.1
      UniProtKB/Swiss-Prot
      Q7TN31
      UniProtKB/TrEMBL
      Q3V1B3
      Related
      ENSMUSP00000022189.8, OTTMUSP00000040000, ENSMUST00000022189.8, OTTMUST00000076097
      Conserved Domains (4) summary
      COG1716
      Location:424509
      FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]
      cd00060
      Location:407513
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      pfam01585
      Location:617658
      G-patch; G-patch domain
      cd16164
      Location:200253
      OCRE_VG5Q; OCRE domain found in angiogenic factor VG5Q and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      95350683..95375357 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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