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    LGALS7B galectin 7B [ Homo sapiens (human) ]

    Gene ID: 653499, updated on 30-Jun-2019

    Summary

    Official Symbol
    LGALS7Bprovided by HGNC
    Official Full Name
    galectin 7Bprovided by HGNC
    Primary source
    HGNC:HGNC:34447
    See related
    Ensembl:ENSG00000178934 MIM:617139
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PI7; GAL7; Gal-7; HKL-14; LGALS7
    Summary
    The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:3963) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008]
    Expression
    Restricted expression toward skin (RPKM 506.8) See more
    Orthologs

    Genomic context

    See LGALS7B in Genome Data Viewer
    Location:
    19q13.2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (38789200..38791754)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (39279850..39282394)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene actinin alpha 4 Neighboring gene calpain 12 Neighboring gene galectin 7 Neighboring gene RNA, U6 small nuclear 140, pseudogene Neighboring gene galectin 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC75149, MGC88745

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular exosome HDA PubMed 
    extracellular space TAS
    Traceable Author Statement
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    galectin-7
    Names
    keratinocyte lectin 14
    lectin galactoside-binding soluble 7
    lectin, galactoside-binding, soluble, 7B
    p53-induced gene 1 protein
    p53-induced protein 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042507.4NP_001035972.1  galectin-7

      See identical proteins and their annotated locations for NP_001035972.1

      Status: REVIEWED

      Source sequence(s)
      AC022144, AW015224, BC042911, L07769
      Consensus CDS
      CCDS42565.1
      UniProtKB/Swiss-Prot
      P47929
      Related
      ENSP00000313571.3, ENST00000314980.4
      Conserved Domains (1) summary
      smart00908
      Location:11133
      Gal-bind_lectin; Galactoside-binding lectin

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

      Range
      38789200..38791754
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p13 PATCHES

    Genomic

    1. NW_014040929.1 Reference GRCh38.p13 PATCHES

      Range
      198889..201436
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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