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    Zbtb32 zinc finger and BTB domain containing 32 [ Mus musculus (house mouse) ]

    Gene ID: 58206, updated on 19-Feb-2019

    Summary

    Official Symbol
    Zbtb32provided by MGI
    Official Full Name
    zinc finger and BTB domain containing 32provided by MGI
    Primary source
    MGI:MGI:1891838
    See related
    Ensembl:ENSMUSG00000006310
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rog; FAXF; FAZF; PLZP; Tzfp; 4930524C15Rik
    Expression
    Biased expression in testis adult (RPKM 43.9), spleen adult (RPKM 2.9) and 1 other tissue See more
    Orthologs

    Genomic context

    See Zbtb32 in Genome Data Viewer
    Location:
    7; 7 B1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (30589680..30602820, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (31374700..31377961, complement)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene lysine (K)-specific methyltransferase 2B Neighboring gene predicted gene, 32082 Neighboring gene microRNA 3569 Neighboring gene uroplakin 1A Neighboring gene cytochrome c oxidase, subunit 6B1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    transcription corepressor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    zinc ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    T cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    hemopoiesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of cytokine production IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    nuclear chromosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    zinc finger and BTB domain-containing protein 32
    Names
    GATA repressor
    repressor of GATA
    testis zinc finger protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021397.2NP_067372.2  zinc finger and BTB domain-containing protein 32

      See identical proteins and their annotated locations for NP_067372.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the protein-coding transcript.
      Source sequence(s)
      AC167970, AF241232, AK015881, BY349526
      Consensus CDS
      CCDS21102.1
      UniProtKB/Swiss-Prot
      Q9JKD9
      UniProtKB/TrEMBL
      B2RQ06
      Related
      ENSMUSP00000103786.2, ENSMUST00000108151.2
      Conserved Domains (5) summary
      smart00225
      Location:30112
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:352372
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:350372
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:23109
      BTB; BTB/POZ domain
      pfam13465
      Location:365386
      zf-H2C2_2; Zinc-finger double domain

    RNA

    1. NR_153655.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' end and lacks two alternate internal exons compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding region, including the translational start codon, found in variant 1.
      Source sequence(s)
      AC167970, AK015881, BY742457

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      30589680..30602820 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011250663.2XP_011248965.1  zinc finger and BTB domain-containing protein 32 isoform X3

      Conserved Domains (2) summary
      sd00017
      Location:97117
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:95117
      zf-C2H2; Zinc finger, C2H2 type
    2. XM_006540246.3XP_006540309.1  zinc finger and BTB domain-containing protein 32 isoform X1

      See identical proteins and their annotated locations for XP_006540309.1

      UniProtKB/TrEMBL
      B2RQ06
      Conserved Domains (5) summary
      smart00225
      Location:30112
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:352372
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:350372
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:23109
      BTB; BTB/POZ domain
      pfam13465
      Location:365386
      zf-H2C2_2; Zinc-finger double domain
    3. XM_006540248.3XP_006540311.1  zinc finger and BTB domain-containing protein 32 isoform X2

      Conserved Domains (5) summary
      smart00225
      Location:30112
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:329349
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:327349
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:23109
      BTB; BTB/POZ domain
      pfam13465
      Location:342363
      zf-H2C2_2; Zinc-finger double domain
    4. XM_006540245.3XP_006540308.1  zinc finger and BTB domain-containing protein 32 isoform X1

      See identical proteins and their annotated locations for XP_006540308.1

      UniProtKB/TrEMBL
      B2RQ06
      Conserved Domains (5) summary
      smart00225
      Location:30112
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:352372
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:350372
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:23109
      BTB; BTB/POZ domain
      pfam13465
      Location:365386
      zf-H2C2_2; Zinc-finger double domain
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