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    Ccng1 cyclin G1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25405, updated on 2-Oct-2018

    Summary

    Official Symbol
    Ccng1provided by RGD
    Official Full Name
    cyclin G1provided by RGD
    Primary source
    RGD:2295
    See related
    Ensembl:ENSRNOG00000003256
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    CYCG; Ccng
    Summary
    putative cyclin that appears to be involved in response to cellular growth stimuli but not in the cell cycle [RGD, Feb 2006]
    Expression
    Biased expression in Muscle (RPKM 4545.7), Heart (RPKM 2917.7) and 6 other tissues See more
    Orthologs

    Genomic context

    See Ccng1 in Genome Data Viewer
    Location:
    10q12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (25903925..25910298, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 10 NC_005109.3 (25754109..25760482, complement)

    Chromosome 10 - NC_005109.4Genomic Context describing neighboring genes Neighboring gene hyaluronan-mediated motility receptor Neighboring gene NudC domain containing 2 Neighboring gene similar to 60S ribosomal protein L32 Neighboring gene NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC93642

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    cyclin-dependent protein serine/threonine kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    brain development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    mitotic G2 DNA damage checkpoint IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of cell proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of cyclin-dependent protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of mitotic nuclear division IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    response to organonitrogen compound IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    syncytium formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cyclin-dependent protein kinase holoenzyme complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012923.2NP_037055.1  cyclin-G1

      See identical proteins and their annotated locations for NP_037055.1

      Status: VALIDATED

      Source sequence(s)
      BC081852, CB805791
      UniProtKB/Swiss-Prot
      P39950
      Related
      ENSRNOP00000063905.1, ENSRNOT00000065633.3
      Conserved Domains (1) summary
      pfam00134
      Location:16148
      Cyclin_N; Cyclin, N-terminal domain

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005109.4 Reference Rnor_6.0 Primary Assembly

      Range
      25903925..25910298 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000078.1 Alternate Rn_Celera

      Range
      24735527..24741900 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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