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    Tmem8b transmembrane protein 8B [ Mus musculus (house mouse) ]

    Gene ID: 242409, updated on 6-Mar-2019

    Summary

    Official Symbol
    Tmem8bprovided by MGI
    Official Full Name
    transmembrane protein 8Bprovided by MGI
    Primary source
    MGI:MGI:2441680
    See related
    Ensembl:ENSMUSG00000078716
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4930500O05Rik
    Expression
    Broad expression in testis adult (RPKM 21.3), whole brain E14.5 (RPKM 8.4) and 22 other tissues See more
    Orthologs

    Genomic context

    See Tmem8b in Genome Data Viewer
    Location:
    4; 4 A5-B1
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (43668971..43692668)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (43681843..43705540)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene histidine triad nucleotide binding protein 2 Neighboring gene small EDRK-rich factor 2 pseudogene Neighboring gene family with sequence similarity 221, member B Neighboring gene small EDRK-rich factor 2 pseudogene Neighboring gene olfactory receptor 70 Neighboring gene olfactory receptor 71

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    cell-matrix adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of growth IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001085508.2NP_001078977.1  transmembrane protein 8B isoform 1

      See identical proteins and their annotated locations for NP_001078977.1

      Status: VALIDATED

      Source sequence(s)
      AK029713, AK148848, CB248373, CO042254
      Consensus CDS
      CCDS51168.1
      UniProtKB/Swiss-Prot
      B1AWJ5
      Related
      ENSMUSP00000103497.2, ENSMUST00000107865.8
      Conserved Domains (1) summary
      pfam12036
      Location:245415
      DUF3522; Protein of unknown function (DUF3522)
    2. NM_001355718.1NP_001342647.1  transmembrane protein 8B isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK029713, AK148848, CB248373, CO042254
      Conserved Domains (1) summary
      pfam12036
      Location:285455
      DUF3522; Protein of unknown function (DUF3522)
    3. NM_001368840.1NP_001355769.1  transmembrane protein 8B isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3).
      Source sequence(s)
      AL732626
    4. NM_001368841.1NP_001355770.1  transmembrane protein 8B isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL732626
    5. NM_001368842.1NP_001355771.1  transmembrane protein 8B isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL732626

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      43668971..43692668
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006537910.2XP_006537973.1  transmembrane protein 8B isoform X3

      Conserved Domains (1) summary
      pfam12036
      Location:285455
      DUF3522; Protein of unknown function (DUF3522)
    2. XM_011250027.2XP_011248329.1  transmembrane protein 8B isoform X2

      Related
      ENSMUSP00000103498.2, ENSMUST00000107866.8
      Conserved Domains (1) summary
      pfam12036
      Location:704874
      DUF3522; Protein of unknown function (DUF3522)
    3. XM_011250030.2XP_011248332.1  transmembrane protein 8B isoform X4

      See identical proteins and their annotated locations for XP_011248332.1

      UniProtKB/Swiss-Prot
      B1AWJ5
      Related
      ENSMUSP00000103496.1, ENSMUST00000107864.7
      Conserved Domains (1) summary
      pfam12036
      Location:245415
      DUF3522; Protein of unknown function (DUF3522)
    4. XM_011250028.2XP_011248330.1  transmembrane protein 8B isoform X1

      Conserved Domains (1) summary
      pfam12036
      Location:704821
      DUF3522; Protein of unknown function (DUF3522)

    RNA

    1. XR_001784142.1 RNA Sequence

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