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    Ifne interferon epsilon [ Mus musculus (house mouse) ]

    Gene ID: 230405, updated on 23-May-2018

    Summary

    Official Symbol
    Ifneprovided by MGI
    Official Full Name
    interferon epsilonprovided by MGI
    Primary source
    MGI:MGI:2667156
    See related
    Ensembl:ENSMUSG00000045364 Vega:OTTMUSG00000007692
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ifne1; Ifnt1; Infe1; Ifn-tau-1
    Orthologs

    Genomic context

    See Ifne in Genome Data Viewer
    Location:
    4 C4; 4 42.04 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (88879538..88880201, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (88525442..88526105, complement)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene interferon alpha 1 Neighboring gene predicted gene, 34457 Neighboring gene uncharacterized LOC106557447 Neighboring gene microRNA 31 Neighboring gene predicted gene, 34568

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    • Cytokine-cytokine receptor interaction, organism-specific biosystem (from KEGG)
      Cytokine-cytokine receptor interaction, organism-specific biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
    • Cytokine-cytokine receptor interaction, conserved biosystem (from KEGG)
      Cytokine-cytokine receptor interaction, conserved biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
    • Jak-STAT signaling pathway, organism-specific biosystem (from KEGG)
      Jak-STAT signaling pathway, organism-specific biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
    • Jak-STAT signaling pathway, conserved biosystem (from KEGG)
      Jak-STAT signaling pathway, conserved biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
    • RIG-I-like receptor signaling pathway, organism-specific biosystem (from KEGG)
      RIG-I-like receptor signaling pathway, organism-specific biosystemSpecific families of pattern recognition receptors are responsible for detecting viral pathogens and generating innate immune responses. Non-self RNA appearing in a cell as a result of intracellular ...
    • RIG-I-like receptor signaling pathway, conserved biosystem (from KEGG)
      RIG-I-like receptor signaling pathway, conserved biosystemSpecific families of pattern recognition receptors are responsible for detecting viral pathogens and generating innate immune responses. Non-self RNA appearing in a cell as a result of intracellular ...

    General gene information

    Markers

    Homology

    Clone Names

    • MGC129462, MGC129463

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    cytokine activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytokine receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    type I interferon receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    B cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    B cell proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    T cell activation involved in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    adaptive immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytokine-mediated signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    defense response IEA
    Inferred from Electronic Annotation
    more info
     
    defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    defense response to virus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    humoral immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    natural killer cell activation involved in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of peptidyl-serine phosphorylation of STAT protein IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    response to exogenous dsRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    interferon epsilon
    Names
    IFN-epsilon
    interferon epsilon 1
    interferon tau-1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177348.2NP_796322.1  interferon epsilon precursor

      See identical proteins and their annotated locations for NP_796322.1

      Status: PROVISIONAL

      Source sequence(s)
      AY190044
      Consensus CDS
      CCDS18348.1
      UniProtKB/Swiss-Prot
      Q80ZF2
      Related
      ENSMUSP00000059199.2, OTTMUSP00000008136, ENSMUST00000056014.2, OTTMUST00000017621
      Conserved Domains (1) summary
      pfam00143
      Location:34178
      Interferon; Interferon alpha/beta domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      88879538..88880201 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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