| Egr1 inhibits colon cancer cell proliferation, migration and invasion via regulating CDKL1 at the transcriptional level. | Egr‑1 inhibits colon cancer cell proliferation, migration and invasion via regulating CDKL1 at the transcriptional level.
Shao S, Ju M, Lei J, Lu X, Li H, Wang D, Xia C. | 12/4/2021 |
| Chk1 directly interacts with MYPT1 and preferentially phosphorylates MYPT1 at Ser20, which is essential for MYPT1-PP1cbeta interaction and subsequent Plk1 dephosphorylation. | Chk1 modulates the interaction between myosin phosphatase targeting protein 1 (MYPT1) and protein phosphatase 1cβ (PP1cβ).
Hu X, Li Z, Ding Y, Geng Q, Xiahou Z, Ru H, Dong MQ, Xu X, Li J., Free PMC Article | 09/14/2019 |
| CDKL1 overexpression decreased the chemosensitivity of oral squamous cell carcinoma cells to hydroxycamptothecin. | CDKL1 promotes the chemoresistance of human oral squamous cell carcinoma cells to hydroxycamptothecin.
Li K, Meng Z, Jiang L, Xia C, Xu K, Yuan D, Chen H, Zhang B, Liu S. | 05/11/2019 |
| CDKL1 plays an important role in neuroblastoma cell proliferation, migration and invasion. | Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion.
Li W, Cao J, Liu J, Chu W, Zhang C, Chen S, Kang Z., Free PMC Article | 04/20/2019 |
| CDKL1 was overexpressed in breast cancer patients and had a positive detection efficiency of 77% (144/186). | Evaluation of cyclin-dependent kinase-like 1 expression in breast cancer tissues and its regulation in cancer cell growth.
Tang L, Gao Y, Yan F, Tang J. | 12/22/2012 |
| High expression of CDKL1 protein was associated with gastric cancer. | A role for Cdkl1 in the development of gastric cancer.
Sun W, Yao L, Jiang B, Shao H, Zhao Y, Wang Q. | 12/8/2012 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |