The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis of ccRCC by modulating TGF-beta signaling. | The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis of ccRCC by modulating TGF-β signaling. Cui H, Yi H, Bao H, Tan Y, Tian C, Shi X, Gan D, Zhang B, Liang W, Chen R, Zhu Q, Fang L, Gao X, Huang H, Tian R, Sperling SR, Hu Y, Chen W., Free PMC Article | 08/20/2022 |
The renal cancer risk allele at 14q24.2 activates a novel hypoxia-inducible transcription factor-binding enhancer of DPF3 expression. | The renal cancer risk allele at 14q24.2 activates a novel hypoxia-inducible transcription factor-binding enhancer of DPF3 expression. Protze J, Naas S, Krüger R, Stöhr C, Kraus A, Grampp S, Wiesener M, Schiffer M, Hartmann A, Wullich B, Schödel J., Free PMC Article | 04/30/2022 |
Altered regulation of DPF3, a member of the SWI/SNF complexes, underlies the 14q24 renal cancer susceptibility locus. | Altered regulation of DPF3, a member of the SWI/SNF complexes, underlies the 14q24 renal cancer susceptibility locus. Colli LM, Jessop L, Myers TA, Camp SY, Machiela MJ, Choi J, Cunha R, Onabajo O, Mills GC, Schmid V, Brodie SA, Delattre O, Mole DR, Purdue MP, Yu K, Brown KM, Chanock SJ., Free PMC Article | 09/18/2021 |
downregulation of DPF3 plays an indispensable function in the progression of breast cancer | Downregulation of DPF3 promotes the proliferation and motility of breast cancer cells through activating JAK2/STAT3 signaling. Lin WH, Dai WG, Xu XD, Yu QH, Zhang B, Li J, Li HP. | 06/20/2020 |
DPF3 single nucleotide polymorphisms were significantly correlated with male infertility in a Japanese population. | Association of TUSC1 and DPF3 gene polymorphisms with male infertility. Sato Y, Hasegawa C, Tajima A, Nozawa S, Yoshiike M, Koh E, Kanaya J, Namiki M, Matsumiya K, Tsujimura A, Komatsu K, Itoh N, Eguchi J, Yamauchi A, Iwamoto T., Free PMC Article | 09/22/2018 |
SLC1A1 and DPF3 were strongly associated with idiopathic male infertility and were significantly correlated with semen quality alterations | Strong association of SLC1A1 and DPF3 gene variants with idiopathic male infertility in Han Chinese. Liu SY, Zhang CJ, Peng HY, Sun H, Lin KQ, Huang XQ, Huang K, Chu JY, Yang ZQ., Free PMC Article | 03/31/2018 |
the high resolution crystal structure of the tandem PHD fingers of DPF3b in complex with an H3K14ac peptide. | Crystal structure of DPF3b in complex with an acetylated histone peptide. Li W, Zhao A, Tempel W, Loppnau P, Liu Y. | 12/30/2017 |
Activation of DPF3a upon hypertrophic stimuli in cardiac hypertrophy switches cardiac fetal gene expression from being silenced by HEY to being activated by BRG1. | Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA. Cui H, Schlesinger J, Schoenhals S, Tönjes M, Dunkel I, Meierhofer D, Cano E, Schulz K, Berger MF, Haack T, Abdelilah-Seyfried S, Bulyk ML, Sauer S, Sperling SR., Free PMC Article | 09/3/2016 |
Immunohistochemical staining showed that intensive DPF3 staining occurred in proximal anastomosis and the positive staining was hardly observed in stenotic segment in colon specimens from patients with Hirschsprung's disease | Expression profiles of HA117 and its neighboring gene DPF3 in different colon segments of Hirschsprung's disease. Liu H, Luo Y, Li S, Wang S, Wang N, Jin X., Free PMC Article | 05/16/2015 |
DFP3 protein rs10129954 SNP is associated with poor sperm morphology. | Variants in DPF3 and DSCAML1 are associated with sperm morphology. Kosova G, Hotaling JM, Ohlander S, Niederberger C, Prins GS, Ober C., Free PMC Article | 10/25/2014 |
These findings provide insights in the STAT5 dependent transcriptional regulation of Dpf3. | Identification of a STAT5 target gene, Dpf3, provides novel insights in chronic lymphocytic leukemia. Theodorou M, Speletas M, Mamara A, Papachristopoulou G, Lazou V, Scorilas A, Katsantoni E., Free PMC Article | 06/21/2014 |
by linking RelA and p50 to the SWI/SNF complex, DPF3a/b induces the transactivation of NF-kappaB target gene promoters in relatively inactive chromatin contexts. | Double plant homeodomain (PHD) finger proteins DPF3a and -3b are required as transcriptional co-activators in SWI/SNF complex-dependent activation of NF-κB RelA/p50 heterodimer. Ishizaka A, Mizutani T, Kobayashi K, Tando T, Sakurai K, Fujiwara T, Iba H., Free PMC Article | 06/9/2012 |
three-dimensional solution structures and biochemical analysis of DPF3b highlight the molecular basis of the integrated tandem PHD finger, which acts as one functional unit in the sequence-specific recognition of lysine-14-acetylated histone H3 | Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b. Zeng L, Zhang Q, Li S, Plotnikov AN, Walsh MJ, Zhou MM., Free PMC Article | 08/16/2010 |
DPF3 adds a further layer of complexity to the BAF complex by representing a tissue-specific anchor between histone acetylations as well as methylations and chromatin remodeling. | Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex. Lange M, Kaynak B, Forster UB, Tönjes M, Fischer JJ, Grimm C, Schlesinger J, Just S, Dunkel I, Krueger T, Mebus S, Lehrach H, Lurz R, Gobom J, Rottbauer W, Abdelilah-Seyfried S, Sperling S., Free PMC Article | 01/21/2010 |
Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesCandidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts. Vieira AR, McHenry TG, Daack-Hirsch S, Murray JC, Marazita ML. Genetic polymorphisms in DPF3 associated with risk of breast cancer and lymph node metastases. Hoyal CR, Kammerer S, Roth RB, Reneland R, Marnellos G, Kiechle M, Schwarz-Boeger U, Griffiths LR, Ebner F, Rehbock J, Nelson MR, Braun A. | 03/13/2008 |