| Pro-Survival Factor EDEM3 Confers Therapy Resistance in Prostate Cancer. | Pro-Survival Factor EDEM3 Confers Therapy Resistance in Prostate Cancer.
Scott E, Garnham R, Cheung K, Duxfield A, Elliott DJ, Munkley J., Free PMC Article | 08/6/2022 |
| Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD. | Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD.
George G, Ninagawa S, Yagi H, Furukawa JI, Hashii N, Ishii-Watabe A, Deng Y, Matsushita K, Ishikawa T, Mamahit YP, Maki Y, Kajihara Y, Kato K, Okada T, Mori K., Free PMC Article | 11/27/2021 |
| Bi-allelic variants in the ER quality-control mannosidase gene EDEM3 cause a congenital disorder of glycosylation. | Bi-allelic variants in the ER quality-control mannosidase gene EDEM3 cause a congenital disorder of glycosylation.
Polla DL, Edmondson AC, Duvet S, March ME, Sousa AB, Lehman A, CAUSES Study, Niyazov D, van Dijk F, Demirdas S, van Slegtenhorst MA, Kievit AJA, Schulz C, Armstrong L, Bi X, Rader DJ, Izumi K, Zackai EH, de Franco E, Jorge P, Huffels SC, Hommersom M, Ellard S, Lefeber DJ, Santani A, Hand NJ, van Bokhoven H, He M, de Brouwer APM., Free PMC Article | 09/4/2021 |
| EDEM3 Domains Cooperate to Perform Its Overall Cell Functioning. | EDEM3 Domains Cooperate to Perform Its Overall Cell Functioning.
Manica G, Ghenea S, Munteanu CVA, Martin EC, Butnaru C, Surleac M, Chiritoiu GN, Alexandru PR, Petrescu AJ, Petrescu SM., Free PMC Article | 05/29/2021 |
| IL8 and EDEM3 gene expression ratio indicates peripheral blood mononuclear cell (PBMC) quality. | IL8 and EDEM3 gene expression ratio indicates peripheral blood mononuclear cell (PBMC) quality.
Kofanova O, Bellora C, Quesada RA, Bulla A, Panadero-Fajardo S, Keipes M, Shea K, Stone M, Lescuyer P, Betsou F. | 01/18/2020 |
| the mannose-trimming activity of EDEM3 toward the model misfolded substrate, the glycoprotein T-cell receptor alpha locus (TCRalpha), was reconstituted only when ERp46 had established a covalent interaction with EDEM3 | ER-resident protein 46 (ERp46) triggers the mannose-trimming activity of ER degradation-enhancing α-mannosidase-like protein 3 (EDEM3).
Yu S, Ito S, Wada I, Hosokawa N., Free PMC Article | 02/9/2019 |
| The data corroborated herein suggest that besides ER residents, EDEM3 interacts also with proteins involved in the ERAD cargo recognition and targeting to degradation translocation into the cytosol, including UBA1 and UBA2 ubiquitinating enzymes. In addition, the results indicate that this network of EDEM3 interactors is highly sensitive to interfering with early ER N-glycan processing. | Inhibition of N-glycan processing modulates the network of EDEM3 interactors.
Butnaru CM, Chiritoiu MB, Chiritoiu GN, Petrescu SM, Petrescu AJ. | 06/24/2017 |