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    VCPKMT valosin containing protein lysine methyltransferase [ Homo sapiens (human) ]

    Gene ID: 79609, updated on 5-Mar-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D.

    Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D.
    Petrović S, Roske Y, Rami B, Phan MHQ, Panáková D, Heinemann U., Free PMC Article

    01/28/2023
    METTL21D is the methyltransferase responsible for lysine methylation of VCP.

    Lysine methylation of VCP by a member of a novel human protein methyltransferase family.
    Kernstock S, Davydova E, Jakobsson M, Moen A, Pettersen S, Mælandsmo GM, Egge-Jacobsen W, Falnes PØ.

    05/7/2014
    METTL21D trimethylates Lys-315 in VCP/p97 in a ASPCR1-dependent manner

    A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.
    Cloutier P, Lavallée-Adam M, Faubert D, Blanchette M, Coulombe B., Free PMC Article

    03/7/2013
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