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    C1QA complement C1q A chain [ Homo sapiens (human) ]

    Gene ID: 712, updated on 5-Mar-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    An integrative analysis of single-cell and bulk transcriptome and bidirectional mendelian randomization analysis identified C1Q as a novel stimulated risk gene for Atherosclerosis.

    An integrative analysis of single-cell and bulk transcriptome and bidirectional mendelian randomization analysis identified C1Q as a novel stimulated risk gene for Atherosclerosis.
    Cui HK, Tang CJ, Gao Y, Li ZA, Zhang J, Li YD., Free PMC Article

    01/9/2024
    Complement C1q and von Willebrand factor interaction in atherosclerosis of human carotid artery.

    Complement C1q and von Willebrand factor interaction in atherosclerosis of human carotid artery.
    Schulz K, Donat C, Punjabi M, Glatz K, Kaufmann B, Trendelenburg M., Free PMC Article

    01/8/2024
    Association between serum complement 1q and the associated factors of acute ischemic stroke in patients with type 2 diabetes.

    Association between serum complement 1q and the associated factors of acute ischemic stroke in patients with type 2 diabetes.
    Hu ZP, Wu F, Du YH, Ye M.

    11/6/2023
    Complement Activation-Independent Attenuation of SARS-CoV-2 Infection by C1q and C4b-Binding Protein.

    Complement Activation-Independent Attenuation of SARS-CoV-2 Infection by C1q and C4b-Binding Protein.
    Beirag N, Varghese PM, Neto MM, Al Aiyan A, Khan HA, Qablan M, Shamji MH, Sim RB, Temperton N, Kishore U., Free PMC Article

    07/7/2023
    Complement protein C1q stimulates hyaluronic acid degradation via gC1qR/HABP1/p32 in malignant pleural mesothelioma.

    Complement protein C1q stimulates hyaluronic acid degradation via gC1qR/HABP1/p32 in malignant pleural mesothelioma.
    Balduit A, Vidergar R, Zacchi P, Mangogna A, Agostinis C, Grandolfo M, Bottin C, Salton F, Confalonieri P, Rocca A, Zanconati F, Confalonieri M, Kishore U, Ghebrehiwet B, Bulla R., Free PMC Article

    06/23/2023
    Roles of mesangial C3 and C1q deposition in the clinical manifestations and prognosis of IgAN.

    Roles of mesangial C3 and C1q deposition in the clinical manifestations and prognosis of IgAN.
    Wang S, Dong L, Qin A, Tan J, Zhou X, Qin W.

    06/19/2023
    Gene polymorphisms within regions of complement component C1q in HIV associated preeclampsia.

    Gene polymorphisms within regions of complement component C1q in HIV associated preeclampsia.
    Govender S, Nayak NR, Nandlal L, Naicker T.

    02/27/2023
    Complement component C1q initiates extrinsic coagulation via the receptor for the globular head of C1q in adventitial fibroblasts and vascular smooth muscle cells.

    Complement component C1q initiates extrinsic coagulation via the receptor for the globular head of C1q in adventitial fibroblasts and vascular smooth muscle cells.
    Freda CT, Yin W, Ghebrehiwet B, Rubenstein DA., Free PMC Article

    02/4/2023
    C1QA, C1QB, and GZMB are novel prognostic biomarkers of skin cutaneous melanoma relating tumor microenvironment.

    C1QA, C1QB, and GZMB are novel prognostic biomarkers of skin cutaneous melanoma relating tumor microenvironment.
    Liang Z, Pan L, Shi J, Zhang L., Free PMC Article

    12/10/2022
    Neuroinflammation and psychiatric disorders: Relevance of C1q, translocator protein (18 kDa) (TSPO), and neurosteroids.

    Neuroinflammation and psychiatric disorders: Relevance of C1q, translocator protein (18 kDa) (TSPO), and neurosteroids.
    Rupprecht R, Rupprecht C, Di Benedetto B, Rammes G.

    11/5/2022
    Complement-Binding Donor-Specific Anti-HLA Antibodies: Biomarker for Immunologic Risk Stratification in Pediatric Kidney Transplantation Recipients.

    Complement-Binding Donor-Specific Anti-HLA Antibodies: Biomarker for Immunologic Risk Stratification in Pediatric Kidney Transplantation Recipients.
    Sigurjonsdottir VK, Purington N, Chaudhuri A, Zhang BM, Fernandez-Vina M, Palsson R, Kambham N, Charu V, Piburn K, Maestretti L, Shah A, Gallo A, Concepcion W, Grimm PC., Free PMC Article

    09/17/2022
    Serum complement C1q level is associated with left ventricular hypertrophy induced by coarctation of the aorta: A retrospective observational study.

    Serum complement C1q level is associated with left ventricular hypertrophy induced by coarctation of the aorta: A retrospective observational study.
    Chen L, Duan HZ, Zhang C, Li G, Wu YT, Wang D, Li XY., Free PMC Article

    08/27/2022
    Potential biomarkers of spinal dural arteriovenous fistula: C4BPA and C1QA.

    Potential biomarkers of spinal dural arteriovenous fistula: C4BPA and C1QA.
    Wang Y, Ma Y, Yang C, Huang X, Yang K, Lan F, Fu J, Song Z, Tian A, Feng Y, Tu T, Li H, Hong T, Wang Y, Zhang H., Free PMC Article

    07/2/2022
    Activation of complement C1q and C3 in glomeruli might accelerate the progression of diabetic nephropathy: Evidence from transcriptomic data and renal histopathology.

    Activation of complement C1q and C3 in glomeruli might accelerate the progression of diabetic nephropathy: Evidence from transcriptomic data and renal histopathology.
    Jiao Y, Jiang S, Wang Y, Yu T, Zou G, Zhuo L, Li W., Free PMC Article

    05/21/2022
    The collagen structure of C1q induces wound healing by engaging discoidin domain receptor 2.

    The collagen structure of C1q induces wound healing by engaging discoidin domain receptor 2.
    Hayuningtyas RA, Han M, Choi S, Kwak MS, Park IH, Lee JH, Choi JE, Kim DK, Son M, Shin JS., Free PMC Article

    02/26/2022
    C1q-binding DSA and allograft outcomes in pediatric kidney transplant recipients.

    C1q-binding DSA and allograft outcomes in pediatric kidney transplant recipients.
    Hayde N, Solomon S, Caglar E, Ge J, Qama E, Colovai A.

    01/8/2022
    C1q binding to surface-bound IgG is stabilized by C1r2s2 proteases.

    C1q binding to surface-bound IgG is stabilized by C1r(2)s(2) proteases.
    Zwarthoff SA, Widmer K, Kuipers A, Strasser J, Ruyken M, Aerts PC, de Haas CJC, Ugurlar D, den Boer MA, Vidarsson G, van Strijp JAG, Gros P, Parren PWHI, van Kessel KPM, Preiner J, Beurskens FJ, Schuurman J, Ricklin D, Rooijakkers SHM., Free PMC Article

    12/4/2021
    Headless C1q: a new molecular tool to decipher its collagen-like functions.

    Headless C1q: a new molecular tool to decipher its collagen-like functions.
    Fouët G, Bally I, Signor L, Häußermann K, Thielens NM, Rossi V, Gaboriaud C.

    07/31/2021
    Complement in Renal Disease as a Potential Contributor to Arterial Hypertension.

    Complement in Renal Disease as a Potential Contributor to Arterial Hypertension.
    Fischer LM, Fichte LA, Büttner-Herold M, Ferrazzi F, Amann K, Benz K, Daniel C.

    07/17/2021
    Quantification of Complement Proteins with Special Reference to C1q: Multiplex Versus ELISA Versus Rocket Immunoelectrophoresis Versus Nephelometry.

    Quantification of Complement Proteins with Special Reference to C1q: Multiplex Versus ELISA Versus Rocket Immunoelectrophoresis Versus Nephelometry.
    Sandholm K, Persson B, Abdalla S, Mohlin C, Nilsson B, Ekdahl KN.

    06/26/2021
    Clinical and prognostic significance of C1q deposition in IgAN patients-a retrospective study.

    Clinical and prognostic significance of C1q deposition in IgAN patients-a retrospective study.
    Tian S, Yang X, Luo J, Guo H.

    05/29/2021
    Increased Macrophages and C1qA, C3, C4 Transcripts in the Midbrain of People With Schizophrenia.

    Increased Macrophages and C1qA, C3, C4 Transcripts in the Midbrain of People With Schizophrenia.
    Purves-Tyson TD, Robinson K, Brown AM, Boerrigter D, Cai HQ, Weissleder C, Owens SJ, Rothmond DA, Shannon Weickert C., Free PMC Article

    05/22/2021
    Association of Serum Complement C1q Concentration with Severity of Neurological Impairment and Infarct size in Patients with Acute Ischemic Stroke.

    Association of Serum Complement C1q Concentration with Severity of Neurological Impairment and Infarct size in Patients with Acute Ischemic Stroke.
    Wang DD, Hou XH, Li HQ, Xu W, Ma YH, Dong Q, Yu JT, Tan L.

    02/13/2021
    Cigarette smoke-induced reduction of C1q promotes emphysema.

    Cigarette smoke-induced reduction of C1q promotes emphysema.
    Yuan X, Chang CY, You R, Shan M, Gu BH, Madison MC, Diehl G, Perusich S, Song LZ, Cornwell L, Rossen RD, Wetsel R, Kimal R, Coarfa C, Eltzschig HK, Corry DB, Kheradmand F., Free PMC Article

    09/26/2020
    Tumor Cells Hijack Macrophage-Produced Complement C1q to Promote Tumor Growth.

    Tumor Cells Hijack Macrophage-Produced Complement C1q to Promote Tumor Growth.
    Roumenina LT, Daugan MV, Noé R, Petitprez F, Vano YA, Sanchez-Salas R, Becht E, Meilleroux J, Clec'h BL, Giraldo NA, Merle NS, Sun CM, Verkarre V, Validire P, Selves J, Lacroix L, Delfour O, Vandenberghe I, Thuilliez C, Keddani S, Sakhi IB, Barret E, Ferré P, Corvaïa N, Passioukov A, Chetaille E, Botto M, de Reynies A, Oudard SM, Mejean A, Cathelineau X, Sautès-Fridman C, Fridman WH.

    09/12/2020
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