Homo sapiens circular RNA 0003602 (Hsa_circ_0003602) accelerates the tumorigenicity of acute myeloid leukemia by modulating miR-502-5p/IGF1R axis. | Homo sapiens circular RNA 0003602 (Hsa_circ_0003602) accelerates the tumorigenicity of acute myeloid leukemia by modulating miR-502-5p/IGF1R axis. Ye Q, Li N, Zhou K, Liao C. | 03/26/2022 |
Circular RNA SOX5 promotes the proliferation and inhibits the apoptosis of the hepatocellular carcinoma cells by targeting miR-502-5p/synoviolin 1 axis. | Circular RNA SOX5 promotes the proliferation and inhibits the apoptosis of the hepatocellular carcinoma cells by targeting miR-502-5p/synoviolin 1 axis. Cai Y, Jia Y., Free PMC Article | 02/26/2022 |
CircCD44 plays oncogenic roles in triple-negative breast cancer by modulating the miR-502-5p/KRAS and IGF2BP2/Myc axes. | CircCD44 plays oncogenic roles in triple-negative breast cancer by modulating the miR-502-5p/KRAS and IGF2BP2/Myc axes. Li J, Gao X, Zhang Z, Lai Y, Lin X, Lin B, Ma M, Liang X, Li X, Lv W, Lin Y, Zhang N., Free PMC Article | 02/26/2022 |
MicroRNA5023p promotes Mycobacterium tuberculosis survival in macrophages by modulating the inflammatory response by targeting ROCK1. | MicroRNA‑502‑3p promotes Mycobacterium tuberculosis survival in macrophages by modulating the inflammatory response by targeting ROCK1. Liu F, Dong Z, Lin Y, Yang H, Wang P, Zhang Y., Free PMC Article | 01/22/2022 |
Study on Omentin-1 and miR-502-3p in osteoporotic fracture. | Study on Omentin-1 and miR-502-3p in osteoporotic fracture. Zhang J, Hou Y, Wang Z, Zhou P, Zhang P, Wang J, Sun Z, Wang L., Free PMC Article | 01/1/2022 |
MicroRNA miR-502-5p inhibits ovarian cancer genesis by downregulation of GINS complex subunit 2. | MicroRNA miR-502-5p inhibits ovarian cancer genesis by downregulation of GINS complex subunit 2. Zhan L, Yang J, Liu Y, Cheng Y, Liu H., Free PMC Article | 12/25/2021 |
LncRNA LINC00473 is involved in the progression of invasive pituitary adenoma by upregulating KMT5A via ceRNA-mediated miR-502-3p evasion. | LncRNA LINC00473 is involved in the progression of invasive pituitary adenoma by upregulating KMT5A via ceRNA-mediated miR-502-3p evasion. Li J, Qian Y, Zhang C, Wang W, Qiao Y, Song H, Li L, Guo J, Lu D, Deng X., Free PMC Article | 10/16/2021 |
Hsa_circ_0032131 knockdown inhibits osteoarthritis progression via the miR-502-5p/PRDX3 axis. | Hsa_circ_0032131 knockdown inhibits osteoarthritis progression via the miR-502-5p/PRDX3 axis. Xu J, Ma X., Free PMC Article | 07/24/2021 |
Circular RNA circ_001842 plays an oncogenic role in renal cell carcinoma by disrupting microRNA-502-5p-mediated inhibition of SLC39A14. | Circular RNA circ_001842 plays an oncogenic role in renal cell carcinoma by disrupting microRNA-502-5p-mediated inhibition of SLC39A14. Zeng J, Feng Q, Wang Y, Xie G, Li Y, Yang Y, Feng J., Free PMC Article | 05/8/2021 |
Circ_0032627 accelerates proliferation of gastric cancer cells through regulating miR-502-5p expression. | Circ_0032627 accelerates proliferation of gastric cancer cells through regulating miR-502-5p expression. Yin HF, Wang Q, Huang XT, Wang NY, Yuan M, Wu D, Sun X, Qin Y, Fei YH. | 04/17/2021 |
CDKN1B Mediates Apoptosis of Neuronal Cells and Inflammation Induced by Oxyhemoglobin via miR-502-5p After Subarachnoid Hemorrhage. | CDKN1B Mediates Apoptosis of Neuronal Cells and Inflammation Induced by Oxyhemoglobin via miR-502-5p After Subarachnoid Hemorrhage. Chen D, Wang X, Huang J, Cui S, Zhang L. | 01/23/2021 |
Circ_0020397 regulates the viability of vascular smooth muscle cells by up-regulating GREM1 expression via miR-502-5p in intracranial aneurysm. | Circ_0020397 regulates the viability of vascular smooth muscle cells by up-regulating GREM1 expression via miR-502-5p in intracranial aneurysm. Yin K, Liu X. | 01/16/2021 |
CCND1, DNMT3B and NOP14 were identified as direct targets of miR-502-5p. | CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer. Ying Y, Li J, Xie H, Yan H, Jin K, He L, Ma X, Wu J, Xu X, Fang J, Wang X, Zheng X, Liu B, Xie L., Free PMC Article | 03/7/2020 |
Results found that miR-502 was downregulated in gastric cancer (GC) tissues, inhibited cell proliferation and invasion, and reversed the tumor-promoting effects of circDLST in GC cells. | CircDLST promotes the tumorigenesis and metastasis of gastric cancer by sponging miR-502-5p and activating the NRAS/MEK1/ERK1/2 signaling. Zhang J, Hou L, Liang R, Chen X, Zhang R, Chen W, Zhu J., Free PMC Article | 08/24/2019 |
Genetic changes in miR-146a and the miR-502 binding site of the SET8 can be effective on the increased risk of breast cancer. | Study of correlation between genetic variants in three microRNA genes (hsa-miR-146a, hsa-miR-502 binding site, hsa-miR-27a) and breast cancer risk. Parchami Barjui S, Reiisi S, Ebrahimi SO, Shekari B. | 06/8/2019 |
data suggest that persistent elevated levels of miR-502-5p participate in the development of aneurysmal subarachnoid hemorrhage (aSAH) and may help physicians to adjust therapy for aSAH | Persistent High Levels of miR-502-5p Are Associated with Poor Neurologic Outcome in Patients with Aneurysmal Subarachnoid Hemorrhage. Sheng B, Fang X, Liu C, Wu D, Xia D, Xu S, Lai N. | 10/20/2018 |
miR-502 enhanced the phosphorylation levels of AKT pathways, which may be the mechanism of the overgrowth for esophageal cancer cells. | MiR-502 mediates esophageal cancer cell TE1 proliferation by promoting AKT phosphorylation. Xu J, Pan X, Hu Z. | 10/13/2018 |
MiR-502 medaited histone methyltransferase SET8 expression is associated with outcome of esophageal squamous cell carcinoma. | miR-502 medaited histone methyltransferase SET8 expression is associated with outcome of esophageal squamous cell carcinoma. Wang C, Wu J, Zhao Y, Guo Z., Free PMC Article | 06/2/2018 |
miR-502/SET8 regulatory circuit emerges as a key regulator of the pathobiology of breast cancer and a focal point for possible therapeutic intervention. | MiR-502/SET8 regulatory circuit in pathobiology of breast cancer. Liu B, Zhang X, Song F, Zheng H, Zhao Y, Li H, Zhang L, Yang M, Zhang W, Chen K. | 02/18/2017 |
rs56288038 (C/G) in IRF-1 3'UTR acted as a promotion factor in gastric cancer development through enhancing the regulatory role of miR-502-5p in IRF-1 expression. | Rs56288038 (C/G) in 3'UTR of IRF-1 Regulated by MiR-502-5p Promotes Gastric Cancer Development. Wang B, Yang H, Shen L, Wang J, Pu W, Chen Z, Shen X, Fu J, Zhuang Z. | 02/18/2017 |
High MIR502 expression is associated with atypical coronary artery disease. | Altered serum microRNAs as novel diagnostic biomarkers for atypical coronary artery disease. Wang J, Pei Y, Zhong Y, Jiang S, Shao J, Gong J., Free PMC Article | 01/23/2016 |
findings suggest that miR-502 functions as a tumor suppressor in HCC via inhibition of PI3KCG, supporting its utility as a promising therapeutic gene target for this tumor type | miR-502 inhibits cell proliferation and tumor growth in hepatocellular carcinoma through suppressing phosphoinositide 3-kinase catalytic subunit gamma. Chen S, Li F, Chai H, Tao X, Wang H, Ji A. | 11/21/2015 |
miR-502-5p may act as a tumor-suppressor gene by targeting oncogenic TRAF2 in breast cancer and, therefore, may be a potential diagnostic and anticancer therapeutic marker for breast cancer. | Suppressive role of miR-502-5p in breast cancer via downregulation of TRAF2. Sun LL, Wang J, Zhao ZJ, Liu N, Wang AL, Ren HY, Yang F, Diao KX, Fu WN, Wan EH, Mi XY. | 01/17/2015 |
evaluate the impact of rs16917496 polymorphism within the miR-502 miRNA seed region at the 3'UTR of SEDT8 on childhood acute lymphoblastic leukemia | Association of functional polymorphism at the miR-502-binding site in the 3' untranslated region of the SETD8 gene with risk of childhood acute lymphoblastic leukemia, a preliminary report. Hashemi M, Sheybani-Nasab M, Naderi M, Roodbari F, Taheri M. | 01/10/2015 |
The SNP in the miR502 binding site of the SET8 3'-untranslated region seems to influence survival of non-Hodgkin's lymphoma. | Prognostic value of microRNA 502 binding site SNP in the 3'-untranslated region of the SET8 gene in patients with non-Hodgkin's lymphoma. Diao L, Su H, Wei G, Li T, Gao Y, Zhao G, Guo Z. | 12/27/2014 |