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    AKR1B10 aldo-keto reductase family 1 member B10 [ Homo sapiens (human) ]

    Gene ID: 57016, updated on 11-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Aldo-keto Reductase 1B10 Restrains Cell Migration, Invasion, and Adhesion of Gastric Cancer via Regulating Integrin Subunit Alpha 5.

    Aldo-keto Reductase 1B10 Restrains Cell Migration, Invasion, and Adhesion of Gastric Cancer via Regulating Integrin Subunit Alpha 5.
    Yao H, Hu J, Shao Y, Shah Q, Zheng S., Free PMC Article

    12/22/2023
    Serum AKR1B10 as an indicator of unfavorable survival of hepatocellular carcinoma.

    Serum AKR1B10 as an indicator of unfavorable survival of hepatocellular carcinoma.
    Xie C, Ye X, Zeng L, Zeng X, Cao D.

    10/24/2023
    AKR1B10 regulates M2 macrophage polarization to promote the malignant phenotype of gastric cancer.

    AKR1B10 regulates M2 macrophage polarization to promote the malignant phenotype of gastric cancer.
    Wu Y, Hao Y, Zhuang Q, Ma X, Shi C., Free PMC Article

    09/29/2023
    RNF152 Suppresses Fatty Acid Oxidation and Metastasis of Lung Adenocarcinoma by Inhibiting IRAK1-Mediated AKR1B10 Expression.

    RNF152 Suppresses Fatty Acid Oxidation and Metastasis of Lung Adenocarcinoma by Inhibiting IRAK1-Mediated AKR1B10 Expression.
    Zhu D, Nie Y, Zhao Y, Chen X, Yang Z, Yang Y.

    09/28/2023
    Warburg effect enhanced by AKR1B10 promotes acquired resistance to pemetrexed in lung cancer-derived brain metastasis.

    Warburg effect enhanced by AKR1B10 promotes acquired resistance to pemetrexed in lung cancer-derived brain metastasis.
    Duan W, Liu W, Xia S, Zhou Y, Tang M, Xu M, Lin M, Li X, Wang Q., Free PMC Article

    08/19/2023
    Overexpression of AKR1B10 Predicts Poor Prognosis in Gastric Cancer Patients Undergoing Surgical Resection.

    Overexpression of AKR1B10 Predicts Poor Prognosis in Gastric Cancer Patients Undergoing Surgical Resection.
    Liu YY, Liu YW, Huang GK, Hung KC, Lin YH, Yeh CH, Yin SM, Tsai CH, Chen YH., Free PMC Article

    02/4/2023
    AKR1B10 accelerates the production of proinflammatory cytokines via the NF-kappaB signaling pathway in colon cancer.

    AKR1B10 accelerates the production of proinflammatory cytokines via the NF-κB signaling pathway in colon cancer.
    Liu C, Shi L, Li W, Huang Z, Wang S, Xu P, Li T, Li Z, Luo F, Li W, Yan J, Wu T.

    09/24/2022
    Plasma Aldo-Keto Reductase Family 1 Member B10 as a Biomarker Performs Well in the Diagnosis of Nonalcoholic Steatohepatitis and Fibrosis.

    Plasma Aldo-Keto Reductase Family 1 Member B10 as a Biomarker Performs Well in the Diagnosis of Nonalcoholic Steatohepatitis and Fibrosis.
    Park A, Choi SJ, Park S, Kim SM, Lee HE, Joo M, Kim KK, Kim D, Chung DH, Im JB, Jung J, Shin SK, Oh BC, Choi C, Nam S, Lee DH., Free PMC Article

    05/28/2022
    E2F1-mediated AUF1 upregulation promotes HCC development and enhances drug resistance via stabilization of AKR1B10.

    E2F1-mediated AUF1 upregulation promotes HCC development and enhances drug resistance via stabilization of AKR1B10.
    Zhang T, Guan G, Zhang J, Zheng H, Li D, Wang W, Lu F, Chen X., Free PMC Article

    04/23/2022
    AKR1B10, One of the Triggers of Cytokine Storm in SARS-CoV2 Severe Acute Respiratory Syndrome.

    AKR1B10, One of the Triggers of Cytokine Storm in SARS-CoV2 Severe Acute Respiratory Syndrome.
    Chabert C, Vitte AL, Iuso D, Chuffart F, Trocme C, Buisson M, Poignard P, Lardinois B, Debois R, Rousseaux S, Pepin JL, Martinot JB, Khochbin S., Free PMC Article

    02/19/2022
    AKR1B10 inhibits the proliferation and migration of gastric cancer via regulating epithelial-mesenchymal transition.

    AKR1B10 inhibits the proliferation and migration of gastric cancer via regulating epithelial-mesenchymal transition.
    Shao X, Wu J, Yu S, Zhou Y, Zhou C., Free PMC Article

    02/5/2022
    AKR1B10 confers resistance to radiotherapy via FFA/TLR4/NF-kappaB axis in nasopharyngeal carcinoma.

    AKR1B10 confers resistance to radiotherapy via FFA/TLR4/NF-κB axis in nasopharyngeal carcinoma.
    Liu X, Hu Z, Qu J, Li J, Gong K, Wang L, Jiang J, Li X, He R, Duan L, Luo W, Xia C, Luo D., Free PMC Article

    01/22/2022
    Aldo Keto Reductases AKR1B1 and AKR1B10 in Cancer: Molecular Mechanisms and Signaling Networks.

    Aldo Keto Reductases AKR1B1 and AKR1B10 in Cancer: Molecular Mechanisms and Signaling Networks.
    Banerjee S.

    01/8/2022
    The expression and significance of AKR1B10 in laryngeal squamous cell carcinoma.

    The expression and significance of AKR1B10 in laryngeal squamous cell carcinoma.
    Liu J, Ban H, Liu Y, Ni J., Free PMC Article

    12/11/2021
    Homeobox A5 activates p53 pathway to inhibit proliferation and promote apoptosis of adrenocortical carcinoma cells by inducing Aldo-Keto reductase family 1 member B10 expression.

    Homeobox A5 activates p53 pathway to inhibit proliferation and promote apoptosis of adrenocortical carcinoma cells by inducing Aldo-Keto reductase family 1 member B10 expression.
    Chen D, Shen Z, Cheng X, Wang Q, Zhou J, Ren F, Sun Y, Wang H, Huang R., Free PMC Article

    12/4/2021
    CBX7 suppresses urinary bladder cancer progression via modulating AKR1B10-ERK signaling.

    CBX7 suppresses urinary bladder cancer progression via modulating AKR1B10-ERK signaling.
    Huang Z, Yan Y, Zhu Z, Liu J, He X, Dalangood S, Li M, Tan M, Cai J, Tang P, Huang R, Shen B, Yan J., Free PMC Article

    09/25/2021
    AKR1B10 protects against UVC-induced DNA damage in breast cancer cells.

    AKR1B10 protects against UVC-induced DNA damage in breast cancer cells.
    Zeng Y, Li J, Guo W, Luo W, Liu X, He R, Hu Z, Duan L, Xia C, Luo D.

    08/14/2021
    AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.

    AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
    Li W, Liu C, Huang Z, Shi L, Zhong C, Zhou W, Meng P, Li Z, Wang S, Luo F, Yan J, Wu T.

    07/24/2021
    Evaluation of an aldo-keto reductase gene signature with prognostic significance in colon cancer via activation of epithelial to mesenchymal transition and the p70S6K pathway.

    Evaluation of an aldo-keto reductase gene signature with prognostic significance in colon cancer via activation of epithelial to mesenchymal transition and the p70S6K pathway.
    Demirkol Canlı S, Seza EG, Sheraj I, Gömçeli I, Turhan N, Carberry S, Prehn JHM, Güre AO, Banerjee S.

    05/29/2021
    Prognostic value of aldo-keto reductase family 1 member B10 (AKR1B10) in digestive system cancers: A meta-analysis.

    Prognostic value of aldo-keto reductase family 1 member B10 (AKR1B10) in digestive system cancers: A meta-analysis.
    Liu R, Zheng S, Yang CY, Yu Y, Peng S, Ge Q, Lin Q, Li Q, Shi W, Shao Y., Free PMC Article

    04/24/2021
    Loss of AKR1B10 promotes colorectal cancer cells proliferation and migration via regulating FGF1-dependent pathway.

    Loss of AKR1B10 promotes colorectal cancer cells proliferation and migration via regulating FGF1-dependent pathway.
    Yao Y, Wang X, Zhou D, Li H, Qian H, Zhang J, Jiang L, Wang B, Lin Q, Zhu X., Free PMC Article

    03/20/2021
    [Aldo-keto reductase family 1 B10 participates in the regulation of hepatoma cell cycle through p27/p-Rb signaling pathway].

    [Aldo-keto reductase family 1 B10 participates in the regulation of hepatoma cell cycle through p27/p-Rb signaling pathway].
    Geng N, Jin YY, Zhu SX, Li YR, Zheng LY, Zhu WJ, Li YW, Han C, Dou XG, Bai H.

    10/31/2020
    KR1B10 was significantly elevated in lung cancer BM, and defined the value of AKR1B10 as a diagnostic serum biomarker for lung cancer patients suffering from BM.

    AKR1B10 (Aldo-keto reductase family 1 B10) promotes brain metastasis of lung cancer cells in a multi-organ microfluidic chip model.
    Liu W, Song J, Du X, Zhou Y, Li Y, Li R, Lyu L, He Y, Hao J, Ben J, Wang W, Shi H, Wang Q.

    06/27/2020
    Serum AKR1B10 reflects advanced Brunt stage 4 liver fibrosis in nonalcoholic steatohepatitis patients; combined with serum Wisteria floribunda agglutinin-positive Mac-2 binding protein, it can predict hepatocellular carcinoma development, gastroesophageal varix formation, and poor prognosis

    Serum aldo-keto reductase family 1 member B10 predicts advanced liver fibrosis and fatal complications of nonalcoholic steatohepatitis.
    Kanno M, Kawaguchi K, Honda M, Horii R, Takatori H, Shimakami T, Kitamura K, Arai K, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Kaneko S.

    06/20/2020
    The systematic analysis of transcriptomic studies performed here revealed a potential critical link between AKR1B10 expression, smoking and occurrence of lung cancer.

    Systems biology analysis of publicly available transcriptomic data reveals a critical link between AKR1B10 gene expression, smoking and occurrence of lung cancer.
    Cubillos-Angulo JM, Fukutani ER, Cruz LAB, Arriaga MB, Lima JV, Andrade BB, Queiroz ATL, Fukutani KF., Free PMC Article

    05/2/2020
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