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    INTS9 integrator complex subunit 9 [ Homo sapiens (human) ]

    Gene ID: 55756, updated on 3-Apr-2024

    GeneRIFs: Gene References Into Functions

    Submit: New GeneRIFCorrection

    GeneRIFPubMed TitleDate
    INTS4 is a specific and conserved interaction partner of INTS9/11 that does not interact with either subunit individually.

    Integrator subunit 4 is a 'Symplekin-like' scaffold that associates with INTS9/11 to form the Integrator cleavage module.
    Albrecht TR, Shevtsov SP, Wu Y, Mascibroda LG, Peart NJ, Huang KL, Sawyer IA, Tong L, Dundr M, Wagner EJ., Free PMC Article

    		08/10/2019
    Functional studies demonstrate that the IntS9-IntS11 interaction is crucial for the role of INT in snRNA 3'-end processing.

    Molecular basis for the interaction between Integrator subunits IntS9 and IntS11 and its functional importance.
    Wu Y, Albrecht TR, Baillat D, Wagner EJ, Tong L., Free PMC Article

    		05/19/2018
    The specific heterodimeric interaction between IntS9 and IntS11 is mediated by a discrete domain present at the extreme C terminus of IntS9 and within the C terminus of IntS11, adjacent to the predicted active site of this endonuclease.

    snRNA 3' end formation requires heterodimeric association of integrator subunits.
    Albrecht TR, Wagner EJ., Free PMC Article

    		04/14/2012
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