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    OPRM1 opioid receptor mu 1 [ Homo sapiens (human) ]

    Gene ID: 4988, updated on 16-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Variation in the mu-opioid receptor gene (OPRM1) moderates the influence of maternal sensitivity on child attachment.

    Variation in the mu-opioid receptor gene (OPRM1) moderates the influence of maternal sensitivity on child attachment.
    Tchalova K, Lydon JE, Atkinson L, Fleming AS, Kennedy J, Lecompte V, Meaney MJ, Moss E, O'Donnell KA, O'Donnell KJ, Silveira PP, Sokolowski MB, Steiner M, Bartz JA., Free PMC Article

    04/16/2024
    Accumbal mu-opioid receptors and salt taste-elicited hedonic responses in a rodent model of prenatal adversity, and their correlates using human functional genomics.

    Accumbal μ-opioid receptors and salt taste-elicited hedonic responses in a rodent model of prenatal adversity, and their correlates using human functional genomics.
    Bischoff AR, Dalle Molle R, Mucellini AB, Pokhvisneva I, Levitan RD, Meaney MJ, Silveira PP.

    03/29/2024
    OPRM1 Gene Polymorphism in Women with Alcohol Use Disorder.

    OPRM1 Gene Polymorphism in Women with Alcohol Use Disorder.
    Boroń A, Suchanecka A, Chmielowiec K, Śmiarowska M, Chmielowiec J, Strońska-Pluta A, Recław R, Grzywacz A., Free PMC Article

    03/15/2024
    A novel tetra-primer ARMS-PCR for genotyping of the OPRM1 gene rs1799971 variant associated with opioid use disorders.

    A novel tetra-primer ARMS-PCR for genotyping of the OPRM1 gene rs1799971 variant associated with opioid use disorders.
    Wijekumar PJ, Ranadeva NDK, Jayamaha AR, Herath HMNDM, Noorden N, Fernando SSN., Free PMC Article

    02/16/2024
    Polymorphisms in the A118G SNP of the OPRM1 gene produce different experiences of opioids: A human laboratory phenotype-genotype assessment.

    Polymorphisms in the A118G SNP of the OPRM1 gene produce different experiences of opioids: A human laboratory phenotype-genotype assessment.
    Dunn KE, Huhn AS, Finan PH, Mange A, Bergeria CL, Maher BS, Rabinowitz JA, Strain EC, Antoine D., Free PMC Article

    02/15/2024
    OPRM1 and BDNF polymorphisms associated with a compensatory neurophysiologic signature in knee osteoarthritis patients.

    OPRM1 and BDNF polymorphisms associated with a compensatory neurophysiologic signature in knee osteoarthritis patients.
    Gonçalves FT, Marques LM, Pessotto AV, Barbosa SP, Imamura M, Simis M, Fregni F, Battistella L.

    12/4/2023
    Effect of OPRM1/COMT gene polymorphisms on sufentanil labor analgesia: a cohort study based on propensity score matching.

    Effect of OPRM1/COMT gene polymorphisms on sufentanil labor analgesia: a cohort study based on propensity score matching.
    Chen Y, Chen Q, Cai C, Lin X, Yu W, Huang H, Xie W, Lin M, Chen W, Wu H, Su T, Wang L.

    11/10/2023
    Allele frequency and genotype distribution of the opioid receptor mu-1 (OPRM1) A118G polymorphism in the Western Saudi population.

    Allele frequency and genotype distribution of the opioid receptor μ-1 (OPRM1) A118G polymorphism in the Western Saudi population.
    Bagher AM, Hareeri RH.

    09/29/2023
    Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to mu-opioidergic cell types.

    Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell types.
    Salimando GJ, Tremblay S, Kimmey BA, Li J, Rogers SA, Wojick JA, McCall NM, Wooldridge LM, Rodrigues A, Borner T, Gardiner KL, Jayakar SS, Singeç I, Woolf CJ, Hayes MR, De Jonghe BC, Bennett FC, Bennett ML, Blendy JA, Platt ML, Creasy KT, Renthal WR, Ramakrishnan C, Deisseroth K, Corder G., Free PMC Article

    09/19/2023
    Cell-type specific molecular architecture for mu opioid receptor function in pain and addiction circuits.

    Cell-type specific molecular architecture for mu opioid receptor function in pain and addiction circuits.
    Ochandarena NE, Niehaus JK, Tassou A, Scherrer G.,

    08/10/2023
    Is OPRM1 genotype a valuable predictor of VAS in patients undergoing laparoscopic radical resection of colorectal cancer with fentanyl?

    Is OPRM1 genotype a valuable predictor of VAS in patients undergoing laparoscopic radical resection of colorectal cancer with fentanyl?
    Zhou Y, Cao L, Yang Y, Gao Y, Li Y, Wang B, Pan B, Huang J, Guo W., Free PMC Article

    05/31/2023
    Toxicity and therapy outcome associations in LIG3, SLCO1B3, ABCB1, OPRM1 and GSTP1 in high-grade serous ovarian cancer.

    Toxicity and therapy outcome associations in LIG3, SLCO1B3, ABCB1, OPRM1 and GSTP1 in high-grade serous ovarian cancer.
    Deng F, Laasik M, Salminen L, Lapatto L, Huhtinen K, Li Y, Hautaniemi S, Hynninen J, Niemi M, Lehtonen R.

    05/28/2023
    Effects of MDR1 and OPRM1 genetic polymorphisms on the pharmacodynamics of propofol-remifentanil TIVA in pediatrics.

    Effects of MDR1 and OPRM1 genetic polymorphisms on the pharmacodynamics of propofol-remifentanil TIVA in pediatrics.
    Liew Y, Capule FR, Rahman RA, Nor NM, Teo R, Makmor-Bakry M.

    04/19/2023
    MOR promotes epithelial-mesenchymal transition and proliferation via PI3K/AKT signaling pathway in human colorectal cancer.

    MOR promotes epithelial-mesenchymal transition and proliferation via PI3K/AKT signaling pathway in human colorectal cancer.
    Gao L, Yang L, He Y, Liu Y, Xu P, Zhang J, Dai S, Luo X, Sun Z., Free PMC Article

    04/5/2023
    Association of OPRM1, MIR23B, and MIR107 genetic variability with acute pain, chronic pain and adverse effects after postoperative tramadol and paracetamol treatment in breast cancer.

    Association of OPRM1, MIR23B, and MIR107 genetic variability with acute pain, chronic pain and adverse effects after postoperative tramadol and paracetamol treatment in breast cancer.
    Vidic Z, Goricar K, Strazisar B, Besic N, Dolzan V., Free PMC Article

    03/28/2023
    Polymorphisms in COMT and OPRM1 Collectively Contribute to Chronic Shoulder Pain and Disability in South African Breast Cancer Survivors'.

    Polymorphisms in COMT and OPRM1 Collectively Contribute to Chronic Shoulder Pain and Disability in South African Breast Cancer Survivors'.
    Firfirey F, Shamley D, September AV., Free PMC Article

    02/11/2023
    Modulation of OPRM1 Alternative Splicing by Morphine and HIV-1 Nef.

    Modulation of OPRM1 Alternative Splicing by Morphine and HIV-1 Nef.
    Donadoni M, Huang W, Yarandi SS, Burdo TH, Chang SL, Sariyer IK., Free PMC Article

    12/17/2022
    Association between rs1799971 in the mu opioid receptor gene and methadone maintenance treatment response.

    Association between rs1799971 in the mu opioid receptor gene and methadone maintenance treatment response.
    Xie X, Gu J, Zhuang D, Zhou Y, Chen X, Shen W, Li L, Liu Y, Xu W, Hong Q, Xu Z, Chen W, Zhou W, Liu H., Free PMC Article

    12/3/2022
    The OPRM1 gene and interactions with the 5-HT1a gene regulate conditioned pain modulation in fibromyalgia patients and healthy controls.

    The OPRM1 gene and interactions with the 5-HT1a gene regulate conditioned pain modulation in fibromyalgia patients and healthy controls.
    Tour J, Sandström A, Kadetoff D, Schalling M, Kosek E., Free PMC Article

    11/19/2022
    No Association between Genetic Variants of the COMT and OPRM1 Genes and Pain Perception among Patients Undergoing Total Hip or Knee Arthroplasty for Primary Osteoarthritis.

    No Association between Genetic Variants of the COMT and OPRM1 Genes and Pain Perception among Patients Undergoing Total Hip or Knee Arthroplasty for Primary Osteoarthritis.
    Jurewicz A, Bohatyrewicz A, Pawlak M, Tarnowski M, Kurzawski M, Machoy-Mokrzyńska A, Kaczmarczyk M, Lubkowska A, Chudecka M, Maciejewska-Skrendo A, Leźnicka K., Free PMC Article

    11/5/2022
    Evidence of alterations of Beta-endorphin levels and Mu-opioid receptor gene expression in bipolar disorder.

    Evidence of alterations of Beta-endorphin levels and Mu-opioid receptor gene expression in bipolar disorder.
    Escelsior A, Sterlini B, Tardito S, Altosole T, Magioncalda P, Martino M, Serafini G, Murri MB, Aguglia A, Amerio A, da Silva BP, Trabucco A, Fenoglio D, Filaci G, Amore M.

    09/24/2022
    The interplay between parental care and OPRM1 in reward responsiveness.

    The interplay between parental care and OPRM1 in reward responsiveness.
    Wang Q, Yang Y, Yu R, Zhao W, Wang M, Wang Y, Guo W, He L, Gong P.

    08/6/2022
    Associations of the A118G OPRM1 polymorphism with sociotropy and interpersonal sensitivity.

    Associations of the A118G OPRM1 polymorphism with sociotropy and interpersonal sensitivity.
    Suzuki A, Shirata T, Noto K, Matsumoto Y, Muraosa H, Abe M, Goto K, Otani K., Free PMC Article

    07/30/2022
    ABCB1 and OPRM1 single-nucleotide polymorphisms collectively modulate chronic shoulder pain and dysfunction in South African breast cancer survivors.

    ABCB1 and OPRM1 single-nucleotide polymorphisms collectively modulate chronic shoulder pain and dysfunction in South African breast cancer survivors.
    Firfirey F, September AV, Shamley D.

    07/2/2022
    Beta 2 adrenergic receptor and mu opioid receptor interact to potentiate the aggressiveness of human breast cancer cell by activating the glycogen synthase kinase 3 signaling.

    Beta 2 adrenergic receptor and mu opioid receptor interact to potentiate the aggressiveness of human breast cancer cell by activating the glycogen synthase kinase 3 signaling.
    Rousseau B, Murugan S, Palagani A, Sarkar DK., Free PMC Article

    05/28/2022
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