Studied three single nucleotide polymorphisms (SNPs) in SCGB1D4 (secretoglobin family 1D member 4) . Found the SNPs to be associated with an increased risk of adenoid hypertrophy, as well as asthma, allergy, sleep-disordered breathing. | Significant association between SCGB1D4 gene polymorphisms and susceptibility to adenoid hypertrophy in a pediatric population. Özdaş T, Özdaş S, Babademez MA, Muz SE, M Atilla H, Baştimur S, Izbirak A, Kurt K, Öz I. | 01/12/2019 |
This interferon-gamma-inducible secretoglobin gene, SCGB1D4, is expressed in virtually all tissues, and the highest level of expression is detectable in lymph nodes, tonsil, cultured lymphoblasts, and the ovary. | IFN-gamma stimulates the expression of a novel secretoglobin that regulates chemotactic cell migration and invasion. Choi MS, Ray R, Zhang Z, Mukherjee AB. | 01/21/2010 |