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    APOF apolipoprotein F [ Homo sapiens (human) ]

    Gene ID: 319, updated on 12-Oct-2019

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Direct interactions between C/EBPalpha and ETS-1 were important for high liver-specific expression of ApoF.

    Transcriptional regulation of the apolipoprotein F (ApoF) gene by ETS and C/EBPα in hepatoma cells.
    Shen XB, Huang L, Zhang SH, Wang DP, Wu YL, Chen WN, Xu SH, Lin X.

    01/16/2016
    this study has identified apoF as likely another target gene of FXR.

    Farnesoid X receptor up-regulates expression of lipid transfer inhibitor protein in liver cells and mice.
    Li L, Liu H, Peng J, Wang Y, Zhang Y, Dong J, Liu X, Guo D, Jiang Y.

    04/5/2014
    LTIP translocation is dependent on LDL lipid composition

    Conversion of lipid transfer inhibitor protein (apolipoprotein F) to its active form depends on LDL composition.
    Morton RE, Greene DJ., Free PMC Article

    03/24/2012
    Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)

    Joint effects of common genetic variants from multiple genes and pathways on the risk of premature coronary artery disease.
    Anderson JL, Horne BD, Camp NJ, Muhlestein JB, Hopkins PN, Cannon-Albright LA, Mower CP, Park JJ, Clarke JL, Nicholas ZP, McKinney JT, Carlquist JF., Free PMC Article

    12/5/2010
    lipoprotein composition may influence the status of lipid transfer inhibitor protein activity

    Control of cholesteryl ester transfer protein activity by sequestration of lipid transfer inhibitor protein in an inactive complex.
    He Y, Greene DJ, Kinter M, Morton RE., Free PMC Article

    01/21/2010
    Observational study of gene-disease association. (HuGE Navigator)See all PubMed (5) articles

    Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease.
    Peloso GM, Demissie S, Collins D, Mirel DB, Gabriel SB, Cupples LA, Robins SJ, Schaefer EJ, Brousseau ME.

    Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?
    Ruaño G, Thompson PD, Kane JP, Pullinger CR, Windemuth A, Seip RL, Kocherla M, Holford TR, Wu AH.

    Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.
    Mosbruger TL, Duggal P, Goedert JJ, Kirk GD, Hoots WK, Tobler LH, Busch M, Peters MG, Rosen HR, Thomas DL, Thio CL.

    Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis.
    Chen SN, Cilingiroglu M, Todd J, Lombardi R, Willerson JT, Gotto AM Jr, Ballantyne CM, Marian AJ.

    Exclusion of CYP46 and APOM as candidate genes for Alzheimer's disease in a French population.
    Kabbara A, Payet N, Cottel D, Frigard B, Amouyel P, Lambert JC.

    03/13/2008
    we have confirmed the negative association between plasma triglyceride levels and Apolipoprotein F previously suggested by a small data set, but now we demonstrate that this effect is seen only in males.

    Lipid transfer inhibitor protein (apolipoprotein F) concentration in normolipidemic and hyperlipidemic subjects.
    Morton RE, Gnizak HM, Greene DJ, Cho KH, Paromov VM.

    01/21/2010
    LTIP tailors CETP-mediated remodeling of HDL3 and HDL2 particles in subclass-specific ways, strongly implicating it as a regulator of HDL metabolism

    Lipid transfer inhibitor protein defines the participation of high density lipoprotein subfractions in lipid transfer reactions mediated by cholesterol ester transfer protein (CETP).
    Paromov VM, Morton RE.

    01/21/2010
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