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    PCOLCE2 procollagen C-endopeptidase enhancer 2 [ Homo sapiens (human) ]

    Gene ID: 26577, updated on 15-Apr-2019

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Procollagen C-endopeptidase protein 2, atherosclerosis and HDL cholesteryl ester catabolism. [Review]

    What does procollagen C-endopeptidase enhancer protein 2 have to do with HDL-cholesteryl ester uptake? Or how I learned to stop worrying and love reverse cholesterol transport?
    Sorci-Thomas MG, Pollard RD, Thomas MJ., Free PMC Article

    Data indicate that PCPE2 accelerates the proteolytic processing of pro-apolipoprotein (apo) AI by enhancing the cleavage of the hexapeptide extension present at the N terminus of apoAI.

    Regulation of apoAI processing by procollagen C-proteinase enhancer-2 and bone morphogenetic protein-1.
    Zhu J, Gardner J, Pullinger CR, Kane JP, Thompson JF, Francone OL., Free PMC Article

    Assignment of Pcolce2 gene, which encodes procollagen C-proteinase enhancer protein 2, to human chromosome 3q23.

    Assignment of the mouse Pcolce2 gene, which encodes procollagen C-proteinase enhancer protein 2, to chromosome 9 and localization of PCOLCE2 to human chromosome 3q23.
    Steiglitz BM, Greenspan DS.

    PCPE2 is shown to be a glycoprotein that differs markedly in the nature of its glycosylation from that of PCPE1

    PCOLCE2 encodes a functional procollagen C-proteinase enhancer (PCPE2) that is a collagen-binding protein differing in distribution of expression and post-translational modification from the previously described PCPE1.
    Steiglitz BM, Keene DR, Greenspan DS.

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