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    TAS2R50 taste 2 receptor member 50 [ Homo sapiens (human) ]

    Gene ID: 259296, updated on 5-Mar-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Bitter Sensing TAS2R50 Mediates the trans-Resveratrol-Induced Anti-inflammatory Effect on Interleukin 6 Release in HGF-1 Cells in Culture.

    Bitter Sensing TAS2R50 Mediates the trans-Resveratrol-Induced Anti-inflammatory Effect on Interleukin 6 Release in HGF-1 Cells in Culture.
    Tiroch J, Sterneder S, Di Pizio A, Lieder B, Hoelz K, Holik AK, Pignitter M, Behrens M, Somoza M, Ley JP, Somoza V.

    11/27/2021
    Bitter Taste Receptors and Chronic Otitis Media.

    Bitter Taste Receptors and Chronic Otitis Media.
    Kaufman AC, Colquitt L, Ruckenstein MJ, Bigelow DC, Eliades SJ, Xiong G, Lin C, Reed DR, Cohen NA.

    10/23/2021
    Polymorphism of TAS2R3, TAS2R5, TAS2R19, and TAS2R50 genes and bitter food intake frequency inelderly woman.

    Polymorphism of TAS2R3, TAS2R5, TAS2R19, and TAS2R50 genes and bitter food intake frequency inelderly woman.
    Mikołajczyk-Stecyna J, Malinowska AM, Chmurzynska A.

    03/27/2021
    genetic association studies in populations in Northern Europe, Maghreb, and Sri Lanka: Data suggest that SNPs in TAS2R50 (rs1376251), TRPM5 (rs800345), and TAS2R16 (rs860170) are associated with cultural food preferences; TAS2R16 (rs860170) strongly differentiates populations and is associated to salicin bitterness perception. (TRPM5 = transient receptor potential cation channel subfamily M member 5)

    A bio-cultural approach to the study of food choice: The contribution of taste genetics, population and culture.
    Risso DS, Giuliani C, Antinucci M, Morini G, Garagnani P, Tofanelli S, Luiselli D.

    03/17/2018
    Assessment of KIF6 genotype is not useful in predicting low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly.

    KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly.
    Akao H, Polisecki E, Kajinami K, Trompet S, Robertson M, Ford I, Jukema JW, de Craen AJ, Westendorp RG, Shepherd J, Packard C, Buckley BM, Schaefer EJ.

    05/26/2012
    TAS2R50 is activated by the natural bitter terpenoids andrographolide and amarogentin.

    The human bitter taste receptor hTAS2R50 is activated by the two natural bitter terpenoids andrographolide and amarogentin.
    Behrens M, Brockhoff A, Batram C, Kuhn C, Appendino G, Meyerhof W.

    02/22/2010
    Observational study of gene-disease association. (HuGE Navigator)See all PubMed (5) articles

    Variations of specific non-candidate genes and risk of myocardial infarction: a replication study.
    Koch W, Hoppmann P, Schömig A, Kastrati A.

    Gene variants associated with ischemic stroke: the cardiovascular health study.
    Luke MM, O'Meara ES, Rowland CM, Shiffman D, Bare LA, Arellano AR, Longstreth WT Jr, Lumley T, Rice K, Tracy RP, Devlin JJ, Psaty BM.

    Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study.
    Shiffman D, O'Meara ES, Bare LA, Rowland CM, Louie JZ, Arellano AR, Lumley T, Rice K, Iakoubova O, Luke MM, Young BA, Malloy MJ, Kane JP, Ellis SG, Tracy RP, Devlin JJ, Psaty BM.

    Associations with myocardial infarction of six polymorphisms selected from a three-stage genome-wide association study.
    Horne BD, Carlquist JF, Muhlestein JB, Nicholas ZP, Anderson JL, Intermountain Heart Collaborative Study Group.

    Identification of four gene variants associated with myocardial infarction.
    Shiffman D, Ellis SG, Rowland CM, Malloy MJ, Luke MM, Iakoubova OA, Pullinger CR, Cassano J, Aouizerat BE, Fenwick RG, Reitz RE, Catanese JJ, Leong DU, Zellner C, Sninsky JJ, Topol EJ, Devlin JJ, Kane JP.

    03/13/2008
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