| Novel roles of cardiac-derived erythropoietin in cardiac development and function. | Novel roles of cardiac-derived erythropoietin in cardiac development and function.
Allwood MA, Edgett BA, Platt MJ, Marrow JP, Coyle-Asbil B, Holjak EJB, Nelson VL, Bangali S, Alshamali R, Jacyniak K, Klein JM, Farquharson L, Romanova N, Northrup V, Ogilvie LM, Ayoub A, Ask K, Vickaryous MK, Hare GMT, Brunt KR, Simpson JA. | 03/7/2024 |
| Endogenous erythropoietin has immunoregulatory functions that limit the expression of autoimmune kidney disease in mice. | Endogenous erythropoietin has immunoregulatory functions that limit the expression of autoimmune kidney disease in mice.
Bin S, Cantarelli C, Horwitz JK, Gentile M, Podestà MA, La Manna G, Heeger PS, Cravedi P., Free PMC Article | 08/4/2023 |
| The transcriptional and regulatory identity of erythropoietin producing cells. | The transcriptional and regulatory identity of erythropoietin producing cells.
Kragesteen BK, Giladi A, David E, Halevi S, Geirsdóttir L, Lempke OM, Li B, Bapst AM, Xie K, Katzenelenbogen Y, Dahl SL, Sheban F, Gurevich-Shapiro A, Zada M, Phan TS, Avellino R, Wang SY, Barboy O, Shlomi-Loubaton S, Winning S, Markwerth PP, Dekalo S, Keren-Shaul H, Kedmi M, Sikora M, Fandrey J, Korneliussen TS, Prchal JT, Rosenzweig B, Yutkin V, Racimo F, Willerslev E, Gur C, Wenger RH, Amit I. | 05/25/2023 |
| Erythropoietin signaling in peripheral macrophages is required for systemic beta-amyloid clearance. | Erythropoietin signaling in peripheral macrophages is required for systemic β-amyloid clearance.
Xu L, Li L, Pan CL, Song JJ, Zhang CY, Wu XH, Hu F, Liu X, Zhang Z, Zhang ZY., Free PMC Article | 11/29/2022 |
| HMGB1-mediated restriction of EPO signaling contributes to anemia of inflammation. | HMGB1-mediated restriction of EPO signaling contributes to anemia of inflammation.
Dulmovits BM, Tang Y, Papoin J, He M, Li J, Yang H, Addorisio ME, Kennedy L, Khan M, Brindley E, Ashley RJ, Ackert-Bicknell C, Hale J, Kurita R, Nakamura Y, Diamond B, Barnes BJ, Hermine O, Gallagher PG, Steiner LA, Lipton JM, Taylor N, Mohandas N, Andersson U, Al-Abed Y, Tracey KJ, Blanc L., Free PMC Article | 06/11/2022 |
| Linking erythropoietin to Treg-dependent allograft survival through myeloid cells. | Linking erythropoietin to Treg-dependent allograft survival through myeloid cells.
Horwitz JK, Bin S, Fairchild RL, Keslar KS, Yi Z, Zhang W, Pavlov VI, Li Y, Madsen JC, Cravedi P, Heeger PS., Free PMC Article | 05/28/2022 |
| Prolyl-4-hydroxylases 2 and 3 control erythropoietin production in renin-expressing cells of mouse kidneys. | Prolyl-4-hydroxylases 2 and 3 control erythropoietin production in renin-expressing cells of mouse kidneys.
Broeker KAE, Fuchs MAA, Schrankl J, Lehrmann C, Schley G, Todorov VT, Hugo C, Wagner C, Kurtz A. | 02/26/2022 |
| The Non-Erythropoietic EPO Analogue Cibinetide Inhibits Osteoclastogenesis In Vitro and Increases Bone Mineral Density in Mice. | The Non-Erythropoietic EPO Analogue Cibinetide Inhibits Osteoclastogenesis In Vitro and Increases Bone Mineral Density in Mice.
Awida Z, Bachar A, Saed H, Gorodov A, Ben-Califa N, Ibrahim M, Kolomansky A, Iden JA, Graniewitz Visacovsky L, Liron T, Hiram-Bab S, Brines M, Gabet Y, Neumann D., Free PMC Article | 01/29/2022 |
| Transforming growth factor-beta1 decreases erythropoietin production through repressing hypoxia-inducible factor 2alpha in erythropoietin-producing cells. | Transforming growth factor-β1 decreases erythropoietin production through repressing hypoxia-inducible factor 2α in erythropoietin-producing cells.
Shih HM, Pan SY, Wu CJ, Chou YH, Chen CY, Chang FC, Chen YT, Chiang WC, Tsai HC, Chen YM, Lin SL., Free PMC Article | 11/27/2021 |
| Receptor-mediated mitophagy regulates EPO production and protects against renal anemia. | Receptor-mediated mitophagy regulates EPO production and protects against renal anemia.
Geng G, Liu J, Xu C, Pei Y, Chen L, Mu C, Wang D, Gao J, Li Y, Liang J, Zhao T, Zhang C, Zhou J, Chen Q, Zhu Y, Shi L., Free PMC Article | 10/23/2021 |
| Renal interstitial fibroblasts coproduce erythropoietin and renin under anaemic conditions. | Renal interstitial fibroblasts coproduce erythropoietin and renin under anaemic conditions.
Miyauchi K, Nakai T, Saito S, Yamamoto T, Sato K, Kato K, Nezu M, Miyazaki M, Ito S, Yamamoto M, Suzuki N., Free PMC Article | 10/16/2021 |
| Bone Marrow Endothelial Cells Take Up Blood-Borne Immune Complexes via Fcgamma Receptor IIb2 in an Erythropoietin-Dependent Manner. | Bone Marrow Endothelial Cells Take Up Blood-Borne Immune Complexes via Fcγ Receptor IIb2 in an Erythropoietin-Dependent Manner.
Ito T, Kometani K, Minato N, Hamazaki Y. | 04/3/2021 |
| Correcting beta-thalassemia by combined therapies that restrict iron and modulate erythropoietin activity. | Correcting β-thalassemia by combined therapies that restrict iron and modulate erythropoietin activity.
Casu C, Pettinato M, Liu A, Aghajan M, Lo Presti V, Lidonnici MR, Munoz KA, O'Hara E, Olivari V, Di Modica SM, Booten S, Guo S, Neil G, Miari R, Shapir N, Zafir-Lavie I, Domev H, Ferrari G, Sitara D, Nai A, Rivella S., Free PMC Article | 03/27/2021 |
| Impact of Erythropoietin Production by Erythroblastic Island Macrophages on Homeostatic Murine Erythropoiesis. | Impact of Erythropoietin Production by Erythroblastic Island Macrophages on Homeostatic Murine Erythropoiesis.
Perron-Deshaies G, St-Louis P, Romero H, Scorza T., Free PMC Article | 03/6/2021 |
| Regulation of muscle and metabolic physiology by hypothalamic erythropoietin independently of its peripheral action. | Regulation of muscle and metabolic physiology by hypothalamic erythropoietin independently of its peripheral action.
Wang Z, Khor S, Cai D., Free PMC Article | 02/27/2021 |
| Erythropoietin regulates metabolic response in mice via receptor expression in adipose tissue, brain, and bone. | Erythropoietin regulates metabolic response in mice via receptor expression in adipose tissue, brain, and bone.
Noguchi CT., Free PMC Article | 01/16/2021 |
| Erythropoietin is a major regulator of thrombopoiesis in thrombopoietin-dependent and -independent contexts. | Erythropoietin is a major regulator of thrombopoiesis in thrombopoietin-dependent and -independent contexts.
Hacein-Bey-Abina S, Estienne M, Bessoles S, Echchakir H, Pederzoli-Ribeil M, Chiron A, Aldaz-Carroll L, Leducq V, Zhang Y, Souyri M, Louache F, Abina AM. | 12/12/2020 |
| Erythropoietin inhibits SGK1-dependent TH17 induction and TH17-dependent kidney disease. | Erythropoietin inhibits SGK1-dependent TH17 induction and TH17-dependent kidney disease.
Donadei C, Angeletti A, Cantarelli C, D'Agati VD, La Manna G, Fiaccadori E, Horwitz JK, Xiong H, Guglielmo C, Hartzell S, Madsen JC, Maggiore U, Heeger PS, Cravedi P., Free PMC Article | 10/24/2020 |
| This suggests a model of neuroplasticity in form of a fundamental regulatory circle, in which neuronal networks-challenged by cognitive tasks-drift into transient hypoxia, thereby triggering neuronal EPO/EPOR expression. | Functional hypoxia drives neuroplasticity and neurogenesis via brain erythropoietin.
Wakhloo D, Scharkowski F, Curto Y, Javed Butt U, Bansal V, Steixner-Kumar AA, Wüstefeld L, Rajput A, Arinrad S, Zillmann MR, Seelbach A, Hassouna I, Schneider K, Qadir Ibrahim A, Werner HB, Martens H, Miskowiak K, Wojcik SM, Bonn S, Nacher J, Nave KA, Ehrenreich H., Free PMC Article | 07/4/2020 |
| Our findings suggest that erythropoietin gene modified mesenchymal stem cells (EPO-MSCs) maybe attenuate bronchopulmonary dysplasia (BPD) injury in early than in late administration by inhibiting inflammation response through down-regulation of the p38MAPK signalling pathway | Timing of erythropoietin modified mesenchymal stromal cell transplantation for the treatment of experimental bronchopulmonary dysplasia.
Zhang Z, Sun C, Wang J, Jiang W, Xin Q, Luan Y., Free PMC Article | 12/14/2019 |
| VEGF as a new player in Epo induction and perivascular Gli1(+)SMA(+)PDGFRbeta(+) cells as a previously unrecognized EPC reservoir that could be harnessed for augmenting Epo synthesis in circumstances such as chronic kidney disease where production by canonical EPCs is compromised. | VEGF expands erythropoiesis via hypoxia-independent induction of erythropoietin in noncanonical perivascular stromal cells.
Greenwald AC, Licht T, Kumar S, Oladipupo SS, Iyer S, Grunewald M, Keshet E., Free PMC Article | 11/9/2019 |
| Anemia could disturb T cell movement in the spleen, which might further affect T cell immune response, with partial involvement of EPO. | Splenomegaly induced by anemia impairs T cell movement in the spleen partially via EPO.
Li Y, Yue H, Yang S, Yuan D, Li L, Zhao J, Zhao L. | 11/2/2019 |
| the deficiency of macrophage erythropoietin (EPO) signaling contributed to delayed acute inflammation resolution in diet-induced obese mice. | The deficiency of macrophage erythropoietin signaling contributes to delayed acute inflammation resolution in diet-induced obese mice.
Luo B, Wang Z, Zhang Z, Shen Z, Zhang Z. | 09/21/2019 |
| MEPO promotes neurogenesis and angiogenesis but suppresses gliogenesis in mice with acute ischemic stroke | MEPO promotes neurogenesis and angiogenesis but suppresses gliogenesis in mice with acute ischemic stroke.
Zhang SJ, Wang RL, Zhao HP, Tao Z, Li JC, Ju F, Han ZP, Ma QF, Liu P, Ma SB, Cao GD, Luo YM. | 06/23/2019 |
| The intranasal EPOexerted neuroprotection was almost abolished when the specific Nrf2 antagonist ATRA was administered intraperitoneally prior to intranasal EPO treatment. | Intranasal erythropoietin ameliorates neurological function impairments and neural pathology in mice with chronic alcoholism by regulating autophagy‑related Nrf2 degradation.
Nie X, Wang W, Wang Q, Zhu D, Song H., Free PMC Article | 06/1/2019 |