USP7-mediated JUND suppresses RCAN2 transcription and elevates NFATC1 to enhance stem cell property in colorectal cancer. | USP7-mediated JUND suppresses RCAN2 transcription and elevates NFATC1 to enhance stem cell property in colorectal cancer. Chang Y, Chen L, Tang J, Chen G, Ji J, Xu M. | 12/5/2023 |
CircIQGAP1 regulates RCAN1 and RCAN2 through the mechanism of ceRNA and promotes the growth of malignant glioma. | CircIQGAP1 regulates RCAN1 and RCAN2 through the mechanism of ceRNA and promotes the growth of malignant glioma. Huang X, Wang Z, Song M, Huan H, Cai Z, Wu B, Shen J, Zhou YL, Shi J. | 11/22/2023 |
Association Between Circulating Regulator of Calcineurin 2 Concentrations With Overweight and Obesity. | Association Between Circulating Regulator of Calcineurin 2 Concentrations With Overweight and Obesity. Wang H, Fang X, Ren Q, Zeng Y, Tan X, Ye T, Fan J, Xu Y., Free PMC Article | 07/2/2022 |
A novel transcriptional complex on the VE-cadherin promoter regulated the downregulation of VE-cadherin in the Down Syndrome Candidate Region 1 isoform 1L-mediated angiogenesis. | A novel transcriptional complex on the VE-cadherin promoter regulated the downregulation of VE-cadherin in the Down Syndrome Candidate Region 1 isoform 1L-mediated angiogenesis. Hou S, Niu G, Liu X, Bourbon PM, Zhang D, Cui P, Zhao K, Zhao D, Zeng H., Free PMC Article | 03/5/2022 |
YAP1, TEF3 and DSCR1-1L is a common signaling pathway downstream of several angiogenic factors that regulates angiogenesis. | The novel axis of YAP1, transcription enhancer factor 3 and Down Syndrome Candidate Region 1 isoform 1L is a common signaling pathway downstream of several angiogenic factors. Cui P, Liu X, Zhao K, Hou S, Chen C, Zhao D, Zeng H. | 07/25/2020 |
Data define RCAN2 as a regulator of cilia function that can compensate for the loss of giantin function. | Regulator of calcineurin-2 is a centriolar protein with a role in cilia length control. Stevenson NL, Bergen DJM, Xu A, Wyatt E, Henry F, McCaughey J, Vuolo L, Hammond CL, Stephens DJ., Free PMC Article | 12/7/2019 |
These results suggest that RCAN2 is involved in tumour progression and is an independent prognostic classifier in patients with gastric cancer | Clinicopathological significance of RCAN2 production in gastric carcinoma. Hattori Y, Sentani K, Shinmei S, Oo HZ, Hattori T, Imai T, Sekino Y, Sakamoto N, Oue N, Niitsu H, Hinoi T, Ohdan H, Yasui W. | 05/11/2019 |
RCAN2 expression is upregulated in human masticatory mucosa during wound healing | Human gingiva transcriptome during wound healing. Wang Y, Tatakis DN. | 03/22/2017 |
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
our data have elucidated the molecular and cellular mechanism whereby PGF(2alpha) regulates CXCL8 expression via the FP receptor in endometrial adenocarcinomas and have highlighted RCAN1-4 as a negative regulator of CXCL8 expression | Prostaglandin F(2alpha)-F-prostanoid receptor regulates CXCL8 expression in endometrial adenocarcinoma cells via the calcium-calcineurin-NFAT pathway. Sales KJ, Maldonado-PĂ©rez D, Grant V, Catalano RD, Wilson MR, Brown P, Williams AR, Anderson RA, Thompson EA, Jabbour HN., Free PMC Article | 03/1/2010 |
DSCR1-L1 is constitutively expressed in endothelial cells and acts similar to DSCR1 in inhibiting calcineurin activity and restraining VEGF-mediated angiogenesis. | Down syndrome candidate region 1-like 1 (DSCR1-L1) mimics the inhibitory effects of DSCR1 on calcineurin signaling in endothelial cells and inhibits angiogenesis. Gollogly LK, Ryeom SW, Yoon SS., Free PMC Article | 01/21/2010 |
the expression of ZAKI-4 isoforms is subjected to distinct hormonal as well as tissue-specific regulation, constituting a complex signalling network through inhibition of calcineurin. | Novel human ZAKI-4 isoforms: hormonal and tissue-specific regulation and function as calcineurin inhibitors. Cao X, Kambe F, Miyazaki T, Sarkar D, Ohmori S, Seo H., Free PMC Article | 01/21/2010 |