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    TXNDC9 thioredoxin domain containing 9 [ Homo sapiens (human) ]

    Gene ID: 10190, updated on 3-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Thioredoxin domain-containing protein 9 protects cells against UV-B-provoked apoptosis via NF-kappaB/p65 activation in cutaneous squamous cell carcinoma.

    Thioredoxin domain-containing protein 9 protects cells against UV-B-provoked apoptosis via NF-κB/p65 activation in cutaneous squamous cell carcinoma.
    Xiao Z, Xu Q, Wang H, Zhou X, Zhu Y, Bao C, Chen L, Zhang P, Lin M, Ji C, Gong T., Free PMC Article

    06/21/2023
    TXNDC9 knockdown inhibits lung adenocarcinoma progression by targeting YWHAG.

    TXNDC9 knockdown inhibits lung adenocarcinoma progression by targeting YWHAG.
    Wang J, Pan X, Li J, Zhao J., Free PMC Article

    05/7/2022
    High level of TXNDC9 predicts poor prognosis and contributes to the NF-kappaB-regulated metastatic potential in gastric cancer.

    High level of TXNDC9 predicts poor prognosis and contributes to the NF-κB-regulated metastatic potential in gastric cancer.
    Yang QC, Hao N, Li RH, Duan YY, Zhang Y.

    02/19/2022
    Thioredoxin domain-containing protein 9 (TXNDC9) contributes to oxaliplatin resistance through regulation of autophagy-apoptosis in colorectal adenocarcinoma.

    Thioredoxin domain-containing protein 9 (TXNDC9) contributes to oxaliplatin resistance through regulation of autophagy-apoptosis in colorectal adenocarcinoma.
    Zhou W, Fang C, Zhang L, Wang Q, Li D, Zhu D.

    10/24/2020
    these studies demonstrate that the TXNDC9-PRDX1 axis plays an important role for ROS to activate AR functions. It provides a proof-of-principle that co-targeting AR and PRDX1 may be more effective to control prostate cancer (PCa) growth.

    TXNDC9 regulates oxidative stress-induced androgen receptor signaling to promote prostate cancer progression.
    Feng T, Zhao R, Sun F, Lu Q, Wang X, Hu J, Wang S, Gao L, Zhou Q, Xiong X, Dong X, Wang L, Han B.

    04/18/2020
    TXNDC9 promotes hepatocellular carcinoma progression by positive regulation of MYC-mediated transcriptional network.

    TXNDC9 promotes hepatocellular carcinoma progression by positive regulation of MYC-mediated transcriptional network.
    Chen D, Zou J, Zhao Z, Tang X, Deng Z, Jia J, Liu S., Free PMC Article

    12/14/2019
    These findings suggest that TXNDC9 gene may function in colorectalcancer development

    TXNDC9 expression in colorectal cancer cells and its influence on colorectal cancer prognosis.
    Lu A, Wangpu X, Han D, Feng H, Zhao J, Ma J, Qu S, Chen X, Liu B, Zheng M.

    03/23/2013
    PhLP3 is important for the maintenance of beta-tubulin levels in mammalian cells.

    Modulation of phosducin-like protein 3 (PhLP3) levels promotes cytoskeletal remodelling in a MAPK and RhoA-dependent manner.
    Hayes NV, Jossé L, Smales CM, Carden MJ., Free PMC Article

    04/28/2012
    antagonistic actions of PhLP3 and prefoldin serve to modulate CCT activity and play a key role in establishing a functional cytoskeleton in vivo

    PhLP3 modulates CCT-mediated actin and tubulin folding via ternary complexes with substrates.
    Stirling PC, Cuéllar J, Alfaro GA, El Khadali F, Beh CT, Valpuesta JM, Melki R, Leroux MR.

    01/21/2010
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