U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    TAF11 TATA-binding protein-associated factor TAF11 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854993, updated on 4-Feb-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    TAF11
    Gene description
    TATA-binding protein-associated factor TAF11
    Primary source
    SGD:S000004477
    Locus tag
    YML015C
    See related
    AllianceGenome:SGD:S000004477
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    TAF40
    Summary
    Enables chromatin binding activity. Involved in RNA polymerase II preinitiation complex assembly. Part of transcription factor TFIID complex. Orthologous to several human genes including TAF11 (TATA-box binding protein associated factor 11). [provided by Alliance of Genome Resources, Apr 2022]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (241989..243029, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Psp2p Neighboring gene salt homeostasis regulator Neighboring gene tRNA (carboxymethyluridine(34)-5-O)-methyltransferase Neighboring gene Ubx2p

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. TFIID-specific yeast TAF40 is essential for the majority of RNA polymerase II-mediated transcription in vivo. Komarnitsky PB, et al. Genes Dev, 1999 Oct 1. PMID 10521393, Free PMC Article
    2. Mapping and functional characterization of the TAF11 interaction with TFIIA. Robinson MM, et al. Mol Cell Biol, 2005 Feb. PMID 15657423, Free PMC Article
    3. TFIIA interacts with TFIID via association with TATA-binding protein and TAF40. Kraemer SM, et al. Mol Cell Biol, 2001 Mar. PMID 11238911, Free PMC Article
    4. TAF-Containing and TAF-independent forms of transcriptionally active TBP in vivo. Kuras L, et al. Science, 2000 May 19. PMID 10818000
    5. Saccharomyces cerevisiae HMO1 interacts with TFIID and participates in start site selection by RNA polymerase II. Kasahara K, et al. Nucleic Acids Res, 2008 Mar. PMID 18187511, Free PMC Article

    See all (57) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Interaction between TAF11 and TFIIA involves two distinct regions of TAF11
      Title: Mapping and functional characterization of the TAF11 interaction with TFIIA.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    contributes_to RNA polymerase II general transcription initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA polymerase II preinitiation complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in RNA polymerase II preinitiation complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in RNA polymerase II preinitiation complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription initiation at RNA polymerase II promoter IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in intracellular organelle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of protein-containing complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIID complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of transcription factor TFIID complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    TATA-binding protein-associated factor TAF11
    NP_013697.1
    • TFIID subunit (40 kDa); involved in RNA polymerase II transcription initiation, similar to histone H3 with atypical histone fold motif of Spt3-like transcription factors

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      241989..243029 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182373.1 → NP_013697.1  TPA: TATA-binding protein-associated factor TAF11 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013697.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZF9, Q04226
      UniProtKB/TrEMBL
      A0A6A5PPG1, A6ZM47, B3LLN7, B5VPB0, C7GLD3, G2WK37, N1P035
      Conserved Domains (1) summary
      COG5251
      Location:31 → 230
      TAF40; Transcription initiation factor TFIID, subunit TAF11 [Transcription]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04226.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous