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    AAP3 amino acid permease 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844074, updated on 7-Sep-2023

    Summary

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    Gene symbol
    AAP3
    Gene description
    amino acid permease 3
    Primary source
    Araport:AT1G77380
    Locus tag
    AT1G77380
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    amino acid permease 3; ATAAP3; F2P24.9; F2P24_9
    Summary
    Amino acid permease which transports basic amino acids.
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    Genomic context

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    See AAP3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Sequence:
    Chromosome: 1; NC_003070.9 (29074879..29077390, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene keratinocyte-associated-like protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene Glutaredoxin family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The amino acid permeases AAP3 and AAP6 are involved in root-knot nematode parasitism of Arabidopsis. Marella HH, et al. Mol Plant Microbe Interact, 2013 Jan. PMID 23194341
    2. Low and high affinity amino acid H+-cotransporters for cellular import of neutral and charged amino acids. Fischer WN, et al. Plant J, 2002 Mar. PMID 12148530
    3. Substrate specificity and expression profile of amino acid transporters (AAPs) in Arabidopsis. Fischer WN, et al. J Biol Chem, 1995 Jul 7. PMID 7608199
    4. Translational Regulation of Metabolic Dynamics during Effector-Triggered Immunity. Yoo H, et al. Mol Plant, 2020 Jan 6. PMID 31568832, Free PMC Article
    5. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The transport of amino acids by AAP3 and AAP6 is important for nematode infection and success of the progeny.
      Title: The amino acid permeases AAP3 and AAP6 are involved in root-knot nematode parasitism of Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_106387.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables amino acid transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within amino acid transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within basic amino acid transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    amino acid permease 3
    NP_177862.1
    • amino acid permease 3 (AAP3); CONTAINS InterPro DOMAIN/s: Amino acid transporter, transmembrane (InterPro:IPR013057); BEST Arabidopsis thaliana protein match is: amino acid permease 2 (TAIR:AT5G09220.1); Has 2346 Blast hits to 2332 proteins in 227 species: Archae - 0; Bacteria - 15; Metazoa - 394; Fungi - 322; Plants - 1373; Viruses - 0; Other Eukaryotes - 242 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      29074879..29077390 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106387.3 → NP_177862.1  amino acid permease 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177862.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39134, Q8LE75
      UniProtKB/TrEMBL
      A0A178W3U1, A0A5S9WV64
      Conserved Domains (1) summary
      pfam01490
      Location:30 → 450
      Aa_trans; Transmembrane amino acid transporter protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39134.2

    Gene LinkOut

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