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    SNRK2.10 SNF1-related protein kinase 2.10 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842385, updated on 15-Oct-2023

    Summary

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    Gene symbol
    SNRK2.10
    Gene description
    SNF1-related protein kinase 2.10
    Primary source
    Araport:AT1G60940
    Locus tag
    AT1G60940
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    SNF1-RELATED KINASE 2B; SNF1-related protein kinase 2.10; SNRK2-10; SRK2B; SUCROSE NONFERMENTING 1-RELATED PROTEIN KINASE 2-10; T7P1.8; T7P1_8
    Summary
    encodes a member of SNF1-related protein kinases (SnRK2) whose activity is activated by ionic (salt) and non-ionic (mannitol) osmotic stress.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    10
    Sequence:
    Chromosome: 1; NC_003070.9 (22439063..22442221, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene AGAMOUS-like 55 Neighboring gene RECQ helicase L4B Neighboring gene 2Fe-2S ferredoxin-like superfamily protein Neighboring gene iron regulated transporter 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The SnRK2.10 kinase mitigates the adverse effects of salinity by protecting photosynthetic machinery. Mazur R, et al. Plant Physiol, 2021 Dec 4. PMID 34632500, Free PMC Article
    2. Phosphoproteomic analysis reveals that dehydrins ERD10 and ERD14 are phosphorylated by SNF1-related protein kinase 2.10 in response to osmotic stress. Maszkowska J, et al. Plant Cell Environ, 2019 Mar. PMID 30338858
    3. Genetics and phosphoproteomics reveal a protein phosphorylation network in the abscisic acid signaling pathway in Arabidopsis thaliana. Umezawa T, et al. Sci Signal, 2013 Apr 9. PMID 23572148
    4. Different phosphorylation mechanisms are involved in the activation of sucrose non-fermenting 1 related protein kinases 2 by osmotic stresses and abscisic acid. Boudsocq M, et al. Plant Mol Biol, 2007 Mar. PMID 17103012
    5. SNF1-Related Protein Kinases SnRK2.4 and SnRK2.10 Modulate ROS Homeostasis in Plant Response to Salt Stress. Szymańska KP, et al. Int J Mol Sci, 2019 Jan 2. PMID 30609769, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The SnRK2.10 kinase mitigates the adverse effects of salinity by protecting photosynthetic machinery.
      Title: The SnRK2.10 kinase mitigates the adverse effects of salinity by protecting photosynthetic machinery.
    2. phosphrylates dehydrins ERD10 and ERD14 in response to osmotic stress
      Title: Phosphoproteomic analysis reveals that dehydrins ERD10 and ERD14 are phosphorylated by SNF1-related protein kinase 2.10 in response to osmotic stress.
    3. SNRK2.10 is involved in the regulation of ROS homeostasis in response to salinity.
      Title: SNF1-Related Protein Kinases SnRK2.4 and SnRK2.10 Modulate ROS Homeostasis in Plant Response to Salt Stress.
    4. SnRK2 was mainly involved in ABA signaling rather than dehydration.
      Title: Genetics and phosphoproteomics reveal a protein phosphorylation network in the abscisic acid signaling pathway in Arabidopsis thaliana.
    5. SnRK2.4 and -2.10 play a role in root growth and architecture in saline conditions.
      Title: The Snf1-related protein kinases SnRK2.4 and SnRK2.10 are involved in maintenance of root system architecture during salt stress.
    6. SnRK2.8-mediated protein phosphorylation is important for NTL6 function to induce a drought-resistance response.
      Title: Controlled nuclear import of the transcription factor NTL6 reveals a cytoplasmic role of SnRK2.8 in the drought-stress response.
    7. Data show that the decuple mutant snrk2.1/2/3/4/5/6/7/8/9/10 grew poorly under hyperosmotic stress conditions but was similar to the wild type in culture media in the absence of osmotic stress.
      Title: Arabidopsis decuple mutant reveals the importance of SnRK2 kinases in osmotic stress responses in vivo.
    8. Data show evidence for the involvement of distinct phosphorylation mechanisms in the activation of SnRK2.6 and SnRK2.10.
      Title: Phospho-site mapping, genetic and in planta activation studies reveal key aspects of the different phosphorylation mechanisms involved in activation of SnRK2s.
    9. Different phosphorylation mechanisms and several signalling pathways are involved in the activation of SnRK2 proteins in response to osmotic stress and Aabscisic acid.
      Title: Different phosphorylation mechanisms are involved in the activation of sucrose non-fermenting 1 related protein kinases 2 by osmotic stresses and abscisic acid.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_104774.6
    NM_179503.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatidic acid binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within lateral root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to osmotic stress IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to osmotic stress IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt stress IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    SNF1-related protein kinase 2.10
    NP_176290.1
    • SNF1-related protein kinase 2.10 (SNRK2.10); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636), Serine/threonine-protein kinase-like, plant (InterPro:IPR015740); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT1G10940.1); Has 111565 Blast hits to 109717 proteins in 3008 species: Archae - 112; Bacteria - 13169; Metazoa - 40737; Fungi - 12092; Plants - 25831; Viruses - 494; Other Eukaryotes - 19130 (source: NCBI BLink).
    NP_849834.1
    • SNF1-related protein kinase 2.10 (SNRK2.10); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636), Serine/threonine-protein kinase-like, plant (InterPro:IPR015740); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT1G10940.1); Has 111565 Blast hits to 109717 proteins in 3008 species: Archae - 112; Bacteria - 13169; Metazoa - 40737; Fungi - 12092; Plants - 25831; Viruses - 494; Other Eukaryotes - 19130 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      22439063..22442221 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179503.3 → NP_849834.1  SNF1-related protein kinase 2.10 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849834.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8L8U6, Q9C958
      UniProtKB/TrEMBL
      A0A178W429, A0A5S9WRD1, A0A654ELI5
      Conserved Domains (1) summary
      cd14662
      Location:3 → 259
      STKc_SnRK2; Catalytic domain of the Serine/Threonine Kinases, Sucrose nonfermenting 1-related protein kinase subfamily 2

    2. NM_104774.6 → NP_176290.1  SNF1-related protein kinase 2.10 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176290.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8L8U6, Q9C958
      UniProtKB/TrEMBL
      A0A178W429, A0A5S9WRD1, A0A654ELI5
      Conserved Domains (1) summary
      cd14662
      Location:3 → 259
      STKc_SnRK2; Catalytic domain of the Serine/Threonine Kinases, Sucrose nonfermenting 1-related protein kinase subfamily 2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C958.1

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