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    Ttn titin [ Rattus norvegicus (Norway rat) ]

    Gene ID: 84015, updated on 11-Apr-2024

    Summary

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    Symbol
    Ttnprovided by RGD
    Full Name
    titinprovided by RGD
    Primary source
    RGD:621114
    See related
    Ensembl:ENSRNOG00000069271 AllianceGenome:RGD:621114
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable several functions, including cytoskeletal protein binding activity; enzyme binding activity; and protein kinase activity. Predicted to be a structural constituent of muscle. Involved in sarcomere organization. Located in I band. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple) and myopathy (multiple). Orthologous to human TTN (titin). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Muscle (RPKM 25011.4) and Heart (RPKM 6759.1) See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    3q24
    Exon count:
    337
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (82059648..82332130, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (61652432..61924912, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (63565160..63837815, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486119 Neighboring gene pleckstrin homology domain containing A3 Neighboring gene FKBP prolyl isomerase 7 Neighboring gene uncharacterized LOC120101583 Neighboring gene coiled-coil domain containing 141 Neighboring gene SEC14 and spectrin domain containing 1 Neighboring gene RNA, U6 small nuclear 480

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Increased Expression of N2BA Titin Corresponds to More Compliant Myofibrils in Athlete's Heart. Kellermayer D, et al. Int J Mol Sci, 2021 Oct 15. PMID 34681770, Free PMC Article
    2. Effects of vigorous isometric muscle contraction on titin stiffness-related contractile properties in rat fast-twitch muscles. Shi J, et al. Am J Physiol Regul Integr Comp Physiol, 2021 Dec 1. PMID 34668430
    3. Inhibition of Histone Deacetylases 4 and 5 Reduces Titin Proteolysis and Prevents Reduction of TTN Gene Expression in Atrophied Rat Soleus Muscle after Seven-Day Hindlimb Unloading. Gritsyna YV, et al. Dokl Biochem Biophys, 2020 Nov. PMID 33368047
    4. Titin truncations lead to impaired cardiomyocyte autophagy and mitochondrial function in vivo. Zhou J, et al. Hum Mol Genet, 2019 Jun 15. PMID 30715350
    5. Truncations of the titin Z-disc predispose to a heart failure with preserved ejection phenotype in the context of pressure overload. Ye L, et al. PLoS One, 2018. PMID 30063764, Free PMC Article

    See all (77) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Rbm20 ablation is associated with changes in the expression of titin-interacting and metabolic proteins.
      Title: Rbm20 ablation is associated with changes in the expression of titin-interacting and metabolic proteins.
    2. Increased Expression of N2BA Titin Corresponds to More Compliant Myofibrils in Athlete's Heart.
      Title: Increased Expression of N2BA Titin Corresponds to More Compliant Myofibrils in Athlete's Heart.
    3. Effects of vigorous isometric muscle contraction on titin stiffness-related contractile properties in rat fast-twitch muscles.
      Title: Effects of vigorous isometric muscle contraction on titin stiffness-related contractile properties in rat fast-twitch muscles.
    4. Inhibition of Histone Deacetylase 1 Prevents the Decrease in Titin (Connectin) Content and Development of Atrophy in Rat m. soleus after 3-Day Hindlimb Unloading.
      Title: Inhibition of Histone Deacetylase 1 Prevents the Decrease in Titin (Connectin) Content and Development of Atrophy in Rat m. soleus after 3-Day Hindlimb Unloading.
    5. Inhibition of Histone Deacetylases 4 and 5 Reduces Titin Proteolysis and Prevents Reduction of TTN Gene Expression in Atrophied Rat Soleus Muscle after Seven-Day Hindlimb Unloading.
      Title: Inhibition of Histone Deacetylases 4 and 5 Reduces Titin Proteolysis and Prevents Reduction of TTN Gene Expression in Atrophied Rat Soleus Muscle after Seven-Day Hindlimb Unloading.
    6. RBM20-Mediated Pre-mRNA Splicing Has Muscle-Specificity and Differential Hormonal Responses between Muscles and in Muscle Cell Cultures.
      Title: RBM20-Mediated Pre-mRNA Splicing Has Muscle-Specificity and Differential Hormonal Responses between Muscles and in Muscle Cell Cultures.
    7. Titin-truncating variants lead to impaired autophagy and mitochondrial function in the heart. These changes not only provide molecular mechanisms that underlie Titin-truncating variants-associated ventricular remodeling but also offer potential targets for its intervention.
      Title: Titin truncations lead to impaired cardiomyocyte autophagy and mitochondrial function in vivo.
    8. In the context of pressure overload, Z-disc TTNtv is associated with cardiac fibrosis, diastolic dysfunction, and capillary rarefaction in the absence of overt systolic dysfunction.
      Title: Truncations of the titin Z-disc predispose to a heart failure with preserved ejection phenotype in the context of pressure overload.
    9. These findings reveal a major signal transduction pathway for insulin-induced titin alternative splicing, and place RBM20 in a central position in the pathway, which is consistent with the reputed role of RBM20 in titin alternative splicing.
      Title: Insulin regulates titin pre-mRNA splicing through the PI3K-Akt-mTOR kinase axis in a RBM20-dependent manner.
    10. Titin-truncating variant is associated with dilated cardiomyopathy.
      Title: Titin-truncating variants affect heart function in disease cohorts and the general population.
    Submit: New GeneRIF Correction See all GeneRIFs (44)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables actin filament binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables actinin binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables ankyrin binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables calcium ion binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables calmodulin binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables muscle alpha-actinin binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protease binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein serine/threonine kinase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein tyrosine kinase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables structural constituent of muscle ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables structural molecule activity conferring elasticity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables telethonin binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within adult heart development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cardiac muscle cell development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cardiac muscle contraction ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cardiac muscle hypertrophy ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within cardiac muscle tissue morphogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cardiac muscle tissue morphogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within cardiac myofibril assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cardiac myofibril assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within detection of muscle stretch ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within forward locomotion ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in heart development ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within heart growth ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within heart morphogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within in utero embryonic development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in mitotic chromosome condensation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within muscle contraction ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of protein secretion ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein kinase A signaling ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of relaxation of cardiac muscle ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in response to calcium ion ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in sarcomere organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within sarcomere organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in sarcomere organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in sarcomerogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in skeletal muscle myosin thick filament assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in skeletal muscle thin filament assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in somitogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within striated muscle cell development ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within ventricular system development ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in A band ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in I band IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in I band ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in M band ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in Z disc ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in condensed nuclear chromosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in myofibril IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in sarcomere ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in striated muscle thin filament ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    titin
    Names
    titin protein homolog
    NP_114457.1
    XP_038962312.1
    XP_038962313.1
    XP_038962314.1
    XP_038962315.1
    XP_038962316.1
    XP_038962317.1
    XP_038962319.1
    XP_038962321.1
    XP_038962328.1
    XP_038962330.1
    XP_038962331.1
    XP_038962333.1
    XP_038962334.1
    XP_038962335.1
    XP_038962336.1
    XP_038962337.1
    XP_038962340.1
    XP_038962341.1
    XP_038962343.1
    XP_038962344.1
    XP_038962345.1
    XP_038962346.1
    XP_038962348.1
    XP_038962349.1
    XP_038962351.1
    XP_038962352.1
    XP_038962353.1
    XP_038962354.1
    XP_038962356.1
    XP_038962357.1
    XP_038962358.1
    XP_038962359.1
    XP_038962360.1
    XP_038962361.1
    XP_063140759.1
    XP_063140760.1
    XP_063140761.1
    XP_063140763.1
    XP_063140764.1
    XP_063140765.1
    XP_063140766.1
    XP_063140767.1
    XP_063140769.1
    XP_063140770.1
    XP_063140771.1
    XP_063140772.1
    XP_063140773.1
    XP_063140775.1
    XP_063140776.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_032068.1 → NP_114457.1  titin

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      82059648..82332130 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039106393.2 → XP_038962321.1  titin isoform X12

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (22) summary
      cd05747
      Location:34030 → 34121
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:9986 → 10514
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16970 → 17054
      FN3; Fibronectin type 3 domain
      smart00409
      Location:13943 → 14007
      IG; Immunoglobulin
      smart00410
      Location:12785 → 12849
      IG_like; Immunoglobulin like
      PHA03247
      Location:11442 → 11976
      PHA03247; large tegument protein UL36; Provisional
      COG0810
      Location:10821 → 10890
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      PRK12323
      Location:253 → 346
      PRK12323; DNA polymerase III subunit gamma/tau
      cd00063
      Location:26374 → 26466
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32722 → 32998
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10762 → 10786
      PPAK; PPAK motif
      pfam07679
      Location:7061 → 7150
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12692 → 12760
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9368 → 9398
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23628 → 23709
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:33041 → 33130
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:1992 → 2083
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:12081 → 12387
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    2. XM_063284706.1 → XP_063140776.1  titin isoform X43

    3. XM_039106391.2 → XP_038962319.1  titin isoform X10

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (21) summary
      cd05747
      Location:34042 → 34133
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:33956 → 34584
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16982 → 17066
      FN3; Fibronectin type 3 domain
      smart00410
      Location:13955 → 14019
      IG_like; Immunoglobulin like
      PHA03247
      Location:11454 → 11988
      PHA03247; large tegument protein UL36; Provisional
      COG0810
      Location:10833 → 10902
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      PRK12323
      Location:253 → 346
      PRK12323; DNA polymerase III subunit gamma/tau
      cd00063
      Location:26386 → 26478
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32734 → 33010
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10774 → 10798
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12704 → 12772
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23640 → 23721
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:33053 → 33142
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:12093 → 12399
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    4. XM_039106433.2 → XP_038962361.1  titin isoform X49

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (19) summary
      cd05747
      Location:32652 → 32743
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:15592 → 15676
      FN3; Fibronectin type 3 domain
      smart00409
      Location:12565 → 12629
      IG; Immunoglobulin
      smart00410
      Location:11407 → 11471
      IG_like; Immunoglobulin like
      cd00063
      Location:24996 → 25088
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:31344 → 31620
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10669 → 10693
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:11314 → 11382
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:22250 → 22331
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:31663 → 31752
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:10863 → 11193
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    5. XM_063284689.1 → XP_063140759.1  titin isoform X5

    6. XM_039106432.2 → XP_038962360.1  titin isoform X48

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (17) summary
      cd05747
      Location:32847 → 32938
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:15787 → 15871
      FN3; Fibronectin type 3 domain
      smart00410
      Location:12760 → 12824
      IG_like; Immunoglobulin like
      cd00063
      Location:25191 → 25283
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:31539 → 31815
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:11509 → 11577
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:22445 → 22526
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:31858 → 31947
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:10808 → 11225
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    7. XM_039106431.2 → XP_038962359.1  titin isoform X47

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (19) summary
      cd05747
      Location:32958 → 33049
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:15898 → 15982
      FN3; Fibronectin type 3 domain
      smart00409
      Location:12871 → 12935
      IG; Immunoglobulin
      smart00410
      Location:11713 → 11777
      IG_like; Immunoglobulin like
      cd00063
      Location:25302 → 25394
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:31650 → 31926
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10864 → 10888
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:11620 → 11688
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:22556 → 22637
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:31969 → 32058
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11009 → 11315
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    8. XM_039106430.2 → XP_038962358.1  titin isoform X46

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (18) summary
      cd05747
      Location:33014 → 33105
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:15954 → 16038
      FN3; Fibronectin type 3 domain
      smart00410
      Location:12927 → 12991
      IG_like; Immunoglobulin like
      cd00063
      Location:25358 → 25450
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:31706 → 31982
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10864 → 10888
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:11676 → 11744
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:22612 → 22693
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32025 → 32114
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11065 → 11371
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    9. XM_039106429.2 → XP_038962357.1  titin isoform X45

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (18) summary
      cd05747
      Location:33070 → 33161
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16010 → 16094
      FN3; Fibronectin type 3 domain
      smart00409
      Location:12983 → 13047
      IG; Immunoglobulin
      smart00410
      Location:11825 → 11889
      IG_like; Immunoglobulin like
      cd00063
      Location:25414 → 25506
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:31762 → 32038
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:11732 → 11800
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:22668 → 22749
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32081 → 32170
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11121 → 11427
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    10. XM_039106428.2 → XP_038962356.1  titin isoform X44

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (18) summary
      cd05747
      Location:33098 → 33189
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16038 → 16122
      FN3; Fibronectin type 3 domain
      smart00409
      Location:13011 → 13075
      IG; Immunoglobulin
      smart00410
      Location:11853 → 11917
      IG_like; Immunoglobulin like
      cd00063
      Location:25442 → 25534
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:31790 → 32066
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:11760 → 11828
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:22696 → 22777
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32109 → 32198
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11149 → 11455
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    11. XM_039106389.2 → XP_038962317.1  titin isoform X8

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (21) summary
      cd05747
      Location:34048 → 34139
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16988 → 17072
      FN3; Fibronectin type 3 domain
      smart00410
      Location:13961 → 14025
      IG_like; Immunoglobulin like
      PHA03247
      Location:11460 → 11994
      PHA03247; large tegument protein UL36; Provisional
      COG0810
      Location:10807 → 10909
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      PRK12323
      Location:253 → 346
      PRK12323; DNA polymerase III subunit gamma/tau
      cd00063
      Location:26392 → 26484
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32740 → 33016
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10864 → 10888
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12710 → 12778
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23646 → 23727
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:33059 → 33148
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:12099 → 12405
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    12. XM_039106387.2 → XP_038962315.1  titin isoform X4

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (21) summary
      cd05747
      Location:34050 → 34141
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16990 → 17074
      FN3; Fibronectin type 3 domain
      smart00410
      Location:13963 → 14027
      IG_like; Immunoglobulin like
      PHA03247
      Location:11462 → 11996
      PHA03247; large tegument protein UL36; Provisional
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      PRK12323
      Location:253 → 346
      PRK12323; DNA polymerase III subunit gamma/tau
      cd00063
      Location:26394 → 26486
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32742 → 33018
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12712 → 12780
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23648 → 23729
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:33061 → 33150
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:12101 → 12407
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    13. XM_039106426.2 → XP_038962354.1  titin isoform X42

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (20) summary
      cd05747
      Location:33306 → 33397
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16246 → 16330
      FN3; Fibronectin type 3 domain
      smart00409
      Location:13219 → 13283
      IG; Immunoglobulin
      smart00410
      Location:12061 → 12125
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25650 → 25742
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:31998 → 32274
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:11968 → 12036
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:22904 → 22985
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32317 → 32406
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11517 → 11847
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    14. XM_039106421.2 → XP_038962349.1  titin isoform X35

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (19) summary
      cd05747
      Location:33417 → 33508
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16357 → 16441
      FN3; Fibronectin type 3 domain
      smart00410
      Location:13330 → 13394
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25761 → 25853
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32109 → 32385
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12079 → 12147
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23015 → 23096
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32428 → 32517
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11468 → 11774
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    15. XM_063284705.1 → XP_063140775.1  titin isoform X40

    16. XM_063284703.1 → XP_063140773.1  titin isoform X39

    17. XM_039106417.2 → XP_038962345.1  titin isoform X29

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (19) summary
      cd05747
      Location:33473 → 33564
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16413 → 16497
      FN3; Fibronectin type 3 domain
      smart00410
      Location:13386 → 13450
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25817 → 25909
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32165 → 32441
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12135 → 12203
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23071 → 23152
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32484 → 32573
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11524 → 11830
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    18. XM_039106412.2 → XP_038962340.1  titin isoform X24

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (19) summary
      cd05747
      Location:33529 → 33620
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16469 → 16553
      FN3; Fibronectin type 3 domain
      smart00410
      Location:13442 → 13506
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25873 → 25965
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32221 → 32497
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:11434 → 11460
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12191 → 12259
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23127 → 23208
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32540 → 32629
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11580 → 11886
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    19. XM_063284701.1 → XP_063140771.1  titin isoform X34

    20. XM_039106407.2 → XP_038962335.1  titin isoform X21

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (19) summary
      cd05747
      Location:33557 → 33648
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:11218 → 11919
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16497 → 16581
      FN3; Fibronectin type 3 domain
      smart00410
      Location:13470 → 13534
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25901 → 25993
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32249 → 32525
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12219 → 12287
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23155 → 23236
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32568 → 32657
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11608 → 11914
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    21. XM_039106425.2 → XP_038962353.1  titin isoform X41

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (19) summary
      cd05747
      Location:33332 → 33423
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16272 → 16356
      FN3; Fibronectin type 3 domain
      smart00410
      Location:13245 → 13309
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25676 → 25768
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32024 → 32300
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:11994 → 12062
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:22930 → 23011
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32343 → 32432
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11543 → 11873
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    22. XM_039106420.2 → XP_038962348.1  titin isoform X33

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (19) summary
      cd05747
      Location:33443 → 33534
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16383 → 16467
      FN3; Fibronectin type 3 domain
      smart00410
      Location:13356 → 13420
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25787 → 25879
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32135 → 32411
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12105 → 12173
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23041 → 23122
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32454 → 32543
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11494 → 11800
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    23. XM_039106415.2 → XP_038962343.1  titin isoform X26

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (19) summary
      cd05747
      Location:33499 → 33590
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16439 → 16523
      FN3; Fibronectin type 3 domain
      smart00410
      Location:13412 → 13476
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25843 → 25935
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32191 → 32467
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12161 → 12229
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23097 → 23178
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32510 → 32599
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11550 → 11856
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    24. XM_039106408.2 → XP_038962336.1  titin isoform X22

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (20) summary
      cd05747
      Location:33555 → 33646
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16495 → 16579
      FN3; Fibronectin type 3 domain
      smart00409
      Location:13468 → 13532
      IG; Immunoglobulin
      smart00410
      Location:12310 → 12374
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25899 → 25991
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32247 → 32523
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12217 → 12285
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23153 → 23234
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32566 → 32655
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11606 → 11912
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    25. XM_039106406.2 → XP_038962334.1  titin isoform X20

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (20) summary
      cd05747
      Location:33583 → 33674
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:11219 → 11945
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16523 → 16607
      FN3; Fibronectin type 3 domain
      smart00409
      Location:13496 → 13560
      IG; Immunoglobulin
      smart00410
      Location:12338 → 12402
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25927 → 26019
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32275 → 32551
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12245 → 12313
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23181 → 23262
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32594 → 32683
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11877 → 12130
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    26. XM_039106424.2 → XP_038962352.1  titin isoform X38

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (20) summary
      cd05747
      Location:33360 → 33451
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16300 → 16384
      FN3; Fibronectin type 3 domain
      smart00409
      Location:13273 → 13337
      IG; Immunoglobulin
      smart00410
      Location:12115 → 12179
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25704 → 25796
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32052 → 32328
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12022 → 12090
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:22958 → 23039
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32371 → 32460
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11571 → 11901
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    27. XM_039106418.2 → XP_038962346.1  titin isoform X31

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (19) summary
      cd05747
      Location:33471 → 33562
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16411 → 16495
      FN3; Fibronectin type 3 domain
      smart00410
      Location:13384 → 13448
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25815 → 25907
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32163 → 32439
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12133 → 12201
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23069 → 23150
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32482 → 32571
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11522 → 11828
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    28. XM_063284702.1 → XP_063140772.1  titin isoform X36

    29. XM_039106413.2 → XP_038962341.1  titin isoform X25

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (19) summary
      cd05747
      Location:33527 → 33618
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16467 → 16551
      FN3; Fibronectin type 3 domain
      smart00410
      Location:13440 → 13504
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25871 → 25963
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32219 → 32495
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12189 → 12257
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23125 → 23206
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32538 → 32627
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11578 → 11884
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    30. XM_039106405.2 → XP_038962333.1  titin isoform X19

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (20) summary
      cd05747
      Location:33583 → 33674
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16523 → 16607
      FN3; Fibronectin type 3 domain
      smart00409
      Location:13496 → 13560
      IG; Immunoglobulin
      smart00410
      Location:12338 → 12402
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25927 → 26019
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32275 → 32551
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:11488 → 11514
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12245 → 12313
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23181 → 23262
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32594 → 32683
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11634 → 11940
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    31. XM_063284699.1 → XP_063140769.1  titin isoform X30

    32. XM_039106402.2 → XP_038962330.1  titin isoform X17

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (20) summary
      cd05747
      Location:33611 → 33702
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:11219 → 11973
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16551 → 16635
      FN3; Fibronectin type 3 domain
      smart00409
      Location:13524 → 13588
      IG; Immunoglobulin
      smart00410
      Location:12366 → 12430
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25955 → 26047
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32303 → 32579
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12273 → 12341
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23209 → 23290
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32622 → 32711
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11662 → 11968
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    33. XM_039106423.2 → XP_038962351.1  titin isoform X37

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (19) summary
      cd05747
      Location:33385 → 33476
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16325 → 16409
      FN3; Fibronectin type 3 domain
      smart00410
      Location:13298 → 13362
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25729 → 25821
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32077 → 32353
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12047 → 12115
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:22983 → 23064
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32396 → 32485
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11596 → 11926
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    34. XM_039106416.2 → XP_038962344.1  titin isoform X28

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (19) summary
      cd05747
      Location:33496 → 33587
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16436 → 16520
      FN3; Fibronectin type 3 domain
      smart00410
      Location:13409 → 13473
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25840 → 25932
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32188 → 32464
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12158 → 12226
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23094 → 23175
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32507 → 32596
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11547 → 11853
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    35. XM_039106409.2 → XP_038962337.1  titin isoform X23

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (20) summary
      cd05747
      Location:33552 → 33643
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16492 → 16576
      FN3; Fibronectin type 3 domain
      smart00409
      Location:13465 → 13529
      IG; Immunoglobulin
      smart00410
      Location:12307 → 12371
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25896 → 25988
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32244 → 32520
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12214 → 12282
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23150 → 23231
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32563 → 32652
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11603 → 11909
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    36. XM_063284700.1 → XP_063140770.1  titin isoform X32

    37. XM_039106403.2 → XP_038962331.1  titin isoform X18

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (19) summary
      cd05747
      Location:33608 → 33699
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16548 → 16632
      FN3; Fibronectin type 3 domain
      smart00410
      Location:13521 → 13585
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25952 → 26044
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32300 → 32576
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:11513 → 11539
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12270 → 12338
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23206 → 23287
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32619 → 32708
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11659 → 11965
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    38. XM_063284697.1 → XP_063140767.1  titin isoform X27

    39. XM_039106400.2 → XP_038962328.1  titin isoform X16

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (19) summary
      cd05747
      Location:33636 → 33727
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16576 → 16660
      FN3; Fibronectin type 3 domain
      smart00410
      Location:13549 → 13613
      IG_like; Immunoglobulin like
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:25980 → 26072
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32328 → 32604
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12298 → 12366
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23234 → 23315
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:32647 → 32736
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:11687 → 11993
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    40. XM_063284696.1 → XP_063140766.1  titin isoform X15

    41. XM_063284695.1 → XP_063140765.1  titin isoform X14

    42. XM_063284693.1 → XP_063140763.1  titin isoform X11

    43. XM_063284691.1 → XP_063140761.1  titin isoform X9

    44. XM_039106386.2 → XP_038962314.1  titin isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (21) summary
      cd05747
      Location:34070 → 34161
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:17010 → 17094
      FN3; Fibronectin type 3 domain
      smart00410
      Location:13983 → 14047
      IG_like; Immunoglobulin like
      PHA03247
      Location:11488 → 12022
      PHA03247; large tegument protein UL36; Provisional
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      PRK12323
      Location:253 → 346
      PRK12323; DNA polymerase III subunit gamma/tau
      cd00063
      Location:26414 → 26506
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32762 → 33038
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12732 → 12800
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23668 → 23749
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:33081 → 33170
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:12127 → 12427
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    45. XM_063284690.1 → XP_063140760.1  titin isoform X6

    46. XM_039106388.2 → XP_038962316.1  titin isoform X7

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (22) summary
      cd05747
      Location:34049 → 34140
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:16989 → 17073
      FN3; Fibronectin type 3 domain
      smart00409
      Location:13962 → 14026
      IG; Immunoglobulin
      smart00410
      Location:12804 → 12868
      IG_like; Immunoglobulin like
      PHA03247
      Location:11488 → 12022
      PHA03247; large tegument protein UL36; Provisional
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      PRK12323
      Location:253 → 346
      PRK12323; DNA polymerase III subunit gamma/tau
      cd00063
      Location:26393 → 26485
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32741 → 33017
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12711 → 12779
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23647 → 23728
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:33060 → 33149
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:12127 → 12433
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    47. XM_063284694.1 → XP_063140764.1  titin isoform X13

    48. XM_039106384.2 → XP_038962312.1  titin isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (22) summary
      cd05747
      Location:34076 → 34167
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10032 → 10560
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:17016 → 17100
      FN3; Fibronectin type 3 domain
      smart00409
      Location:13989 → 14053
      IG; Immunoglobulin
      smart00410
      Location:12831 → 12895
      IG_like; Immunoglobulin like
      PHA03247
      Location:11488 → 12022
      PHA03247; large tegument protein UL36; Provisional
      COG0810
      Location:10867 → 10936
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      PRK12323
      Location:253 → 346
      PRK12323; DNA polymerase III subunit gamma/tau
      cd00063
      Location:26420 → 26512
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32768 → 33044
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10808 → 10832
      PPAK; PPAK motif
      pfam07679
      Location:7107 → 7196
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12738 → 12806
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9414 → 9444
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23674 → 23755
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:33087 → 33176
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2038 → 2129
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:12127 → 12433
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain

    49. XM_039106385.2 → XP_038962313.1  titin isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZUN3
      Conserved Domains (21) summary
      cd05747
      Location:34075 → 34166
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:10031 → 10559
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:17015 → 17099
      FN3; Fibronectin type 3 domain
      smart00410
      Location:13988 → 14052
      IG_like; Immunoglobulin like
      PHA03247
      Location:11487 → 12021
      PHA03247; large tegument protein UL36; Provisional
      COG0810
      Location:10866 → 10935
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      PRK12323
      Location:253 → 346
      PRK12323; DNA polymerase III subunit gamma/tau
      cd00063
      Location:26419 → 26511
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:32767 → 33043
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10807 → 10831
      PPAK; PPAK motif
      pfam07679
      Location:7106 → 7195
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:465 → 504
      Titin_Z; Titin Z
      pfam13927
      Location:12737 → 12805
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:9413 → 9443
      THB; Tri-helix bundle domain
      cd00096
      Location:103 → 106
      Ig; Ig strand A [structural motif]
      cd05748
      Location:23673 → 23754
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:33086 → 33175
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2037 → 2128
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:12126 → 12432
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:103 → 193
      Ig; Immunoglobulin domain
    Nucleotide Protein Strain
    Heading Accession and Version

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