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    PDH-E1 BETA pyruvate dehydrogenase E1 beta [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839891, updated on 11-Apr-2024

    Summary

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    Gene symbol
    PDH-E1 BETA
    Gene description
    pyruvate dehydrogenase E1 beta
    Primary source
    Araport:AT1G30120
    Locus tag
    AT1G30120
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    pyruvate dehydrogenase E1 beta
    Summary
    Encodes a putative plastid pyruvate dehydrogenase E1 beta subunit that is distinct from the mitochondrial pyruvate dehydrogenase E1 beta subunit.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_003070.9 (10584105..10586680, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene nine-cis-epoxycarotenoid dioxygenase 5 Neighboring gene nudix hydrolase homolog 25 Neighboring gene DUF1365 family protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning and molecular analyses of the Arabidopsis thaliana plastid pyruvate dehydrogenase subunits. Johnston ML, et al. Biochim Biophys Acta, 1997 Oct 20. PMID 9393637
    2. Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana. Ferro M, et al. Mol Cell Proteomics, 2003 May. PMID 12766230
    3. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article
    4. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
    5. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_102751.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables pyruvate dehydrogenase (acetyl-transferring) activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in acetyl-CoA biosynthetic process from pyruvate IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within fatty acid biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast stroma HDA PubMed 
    located_in nucleus HDA PubMed 
    part_of pyruvate dehydrogenase complex TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pyruvate dehydrogenase E1 beta
    NP_174304.1
    • pyruvate dehydrogenase E1 beta (PDH-E1 BETA); FUNCTIONS IN: pyruvate dehydrogenase (acetyl-transferring) activity; INVOLVED IN: fatty acid biosynthetic process; LOCATED IN: plastid pyruvate dehydrogenase complex, chloroplast, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Transketolase, C-terminal (InterPro:IPR005476), Transketolase-like, C-terminal (InterPro:IPR015941), Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II (InterPro:IPR009014), Transketolase-like, pyrimidine-binding domain (InterPro:IPR005475); BEST Arabidopsis thaliana protein match is: Transketolase family protein (TAIR:AT2G34590.1); Has 14229 Blast hits to 14219 proteins in 2378 species: Archae - 200; Bacteria - 8952; Metazoa - 481; Fungi - 222; Plants - 270; Viruses - 0; Other Eukaryotes - 4104 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      10584105..10586680 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102751.5 → NP_174304.1  pyruvate dehydrogenase E1 beta [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_174304.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O24458, Q9C6Z3
      UniProtKB/TrEMBL
      A0A178WIN0, A0A5S9WD50
      Conserved Domains (3) summary
      cd07036
      Location:90 → 256
      TPP_PYR_E1-PDHc-beta_like; Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins
      CHL00144
      Location:84 → 406
      odpB; pyruvate dehydrogenase E1 component beta subunit; Validated
      pfam02780
      Location:276 → 397
      Transketolase_C; Transketolase, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C6Z3.1

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